BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

646 related articles for article (PubMed ID: 10232608)

  • 21. The 96 kDa protein kinase activated by oncogenic Ras in Xenopus egg extracts is also activated by constitutively active Mek: activation requires serine/threonine phosphorylation.
    Pan BT; Zhang Y; Brott B; Chen DH
    Oncogene; 1997 Apr; 14(14):1653-60. PubMed ID: 9135066
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family.
    Teramoto H; Coso OA; Miyata H; Igishi T; Miki T; Gutkind JS
    J Biol Chem; 1996 Nov; 271(44):27225-8. PubMed ID: 8910292
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-beta-induced apoptosis in hepatoma cells.
    Kim KY; Kim BC; Xu Z; Kim SJ
    J Biol Chem; 2004 Jul; 279(28):29478-84. PubMed ID: 15069087
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Guanine-nucleotide exchange protein C3G activates JNK1 by a ras-independent mechanism. JNK1 activation inhibited by kinase negative forms of MLK3 and DLK mixed lineage kinases.
    Tanaka S; Hanafusa H
    J Biol Chem; 1998 Jan; 273(3):1281-4. PubMed ID: 9430657
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Rit, a non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways.
    Rusyn EV; Reynolds ER; Shao H; Grana TM; Chan TO; Andres DA; Cox AD
    Oncogene; 2000 Sep; 19(41):4685-94. PubMed ID: 11032018
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU145 cells: possible role in antiproliferation and apoptosis.
    Tyagi A; Agarwal R; Agarwal C
    Oncogene; 2003 Mar; 22(9):1302-16. PubMed ID: 12618755
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Pharmacologic mitogen-activated protein/extracellular signal-regulated kinase kinase/mitogen-activated protein kinase inhibitors interact synergistically with STI571 to induce apoptosis in Bcr/Abl-expressing human leukemia cells.
    Yu C; Krystal G; Varticovksi L; McKinstry R; Rahmani M; Dent P; Grant S
    Cancer Res; 2002 Jan; 62(1):188-99. PubMed ID: 11782377
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Evidence for MEK-independent pathways regulating the prolonged activation of the ERK-MAP kinases.
    Grammer TC; Blenis J
    Oncogene; 1997 Apr; 14(14):1635-42. PubMed ID: 9135064
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Protein kinase-dependent overexpression of the nuclear protein pirin in c-JUN and RAS transformed fibroblasts.
    Bergman AC; Alaiya AA; Wendler W; Binetruy B; Shoshan M; Sakaguchi K; Bergman T; Kronenwett U; Auer G; Appella E; Jörnvall H; Linder S
    Cell Mol Life Sci; 1999 Mar; 55(3):467-71. PubMed ID: 10228560
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Differential contribution of the ERK and JNK mitogen-activated protein kinase cascades to Ras transformation of HT1080 fibrosarcoma and DLD-1 colon carcinoma cells.
    Plattner R; Gupta S; Khosravi-Far R; Sato KY; Perucho M; Der CJ; Stanbridge EJ
    Oncogene; 1999 Mar; 18(10):1807-17. PubMed ID: 10086335
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Direct activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein Kinase/ERK kinase kinase 3 (MEKK) derivative.
    Ellinger-Ziegelbauer H; Brown K; Kelly K; Siebenlist U
    J Biol Chem; 1997 Jan; 272(5):2668-74. PubMed ID: 9006902
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A dominant role for the Raf-MEK pathway in forskolin, 12-O-tetradecanoyl-phorbol acetate, and platelet-derived growth factor-induced CREB (cAMP-responsive element-binding protein) activation, uncoupled from serine 133 phosphorylation in NIH 3T3 cells.
    Seternes OM; Johansen B; Moens U
    Mol Endocrinol; 1999 Jul; 13(7):1071-83. PubMed ID: 10406459
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Radicicol suppresses transformation and restores tropomyosin-2 expression in both ras- and MEK-transformed cells without inhibiting the Raf/MEK/ERK signaling cascade.
    Kim PN; Jonasch E; Mosterman BC; Mier JW; Janssen RA
    Cell Growth Differ; 2001 Nov; 12(11):543-50. PubMed ID: 11714635
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The chimeric protein tyrosine kinase ETV6-NTRK3 requires both Ras-Erk1/2 and PI3-kinase-Akt signaling for fibroblast transformation.
    Tognon C; Garnett M; Kenward E; Kay R; Morrison K; Sorensen PH
    Cancer Res; 2001 Dec; 61(24):8909-16. PubMed ID: 11751416
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes.
    Eblen ST; Slack JK; Weber MJ; Catling AD
    Mol Cell Biol; 2002 Sep; 22(17):6023-33. PubMed ID: 12167697
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Role of the stress-activated protein kinases in endothelin-induced cardiomyocyte hypertrophy.
    Choukroun G; Hajjar R; Kyriakis JM; Bonventre JV; Rosenzweig A; Force T
    J Clin Invest; 1998 Oct; 102(7):1311-20. PubMed ID: 9769323
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Effect of PD 098059, a specific inhibitor of mitogen-activated protein kinase kinase, on urokinase expression and in vitro invasion.
    Simon C; Juarez J; Nicolson GL; Boyd D
    Cancer Res; 1996 Dec; 56(23):5369-74. PubMed ID: 8968087
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The kinase suppressor of Ras (KSR) modulates growth factor and Ras signaling by uncoupling Elk-1 phosphorylation from MAP kinase activation.
    Sugimoto T; Stewart S; Han M; Guan KL
    EMBO J; 1998 Mar; 17(6):1717-27. PubMed ID: 9501093
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Properties of MEKs, the kinases that phosphorylate and activate the extracellular signal-regulated kinases.
    Zheng CF; Guan KL
    J Biol Chem; 1993 Nov; 268(32):23933-9. PubMed ID: 8226933
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Cdc42 induces activation loop phosphorylation and membrane targeting of mixed lineage kinase 3.
    Du Y; Böck BC; Schachter KA; Chao M; Gallo KA
    J Biol Chem; 2005 Dec; 280(52):42984-93. PubMed ID: 16253996
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 33.