219 related articles for article (PubMed ID: 10233205)
1. Methadone N-demethylation in human liver microsomes: lack of stereoselectivity and involvement of CYP3A4.
Foster DJ; Somogyi AA; Bochner F
Br J Clin Pharmacol; 1999 Apr; 47(4):403-12. PubMed ID: 10233205
[TBL] [Abstract][Full Text] [Related]
2. Stereoselective metabolism of methadone N-demethylation by cytochrome P4502B6 and 2C19.
Gerber JG; Rhodes RJ; Gal J
Chirality; 2004 Jan; 16(1):36-44. PubMed ID: 14628297
[TBL] [Abstract][Full Text] [Related]
3. Metabolism of methadone and levo-alpha-acetylmethadol (LAAM) by human intestinal cytochrome P450 3A4 (CYP3A4): potential contribution of intestinal metabolism to presystemic clearance and bioactivation.
Oda Y; Kharasch ED
J Pharmacol Exp Ther; 2001 Sep; 298(3):1021-32. PubMed ID: 11504799
[TBL] [Abstract][Full Text] [Related]
4. Enantiomeric metabolic interactions and stereoselective human methadone metabolism.
Totah RA; Allen KE; Sheffels P; Whittington D; Kharasch ED
J Pharmacol Exp Ther; 2007 Apr; 321(1):389-99. PubMed ID: 17259447
[TBL] [Abstract][Full Text] [Related]
5. Stereo-selective metabolism of methadone by human liver microsomes and cDNA-expressed cytochrome P450s: a reconciliation.
Chang Y; Fang WB; Lin SN; Moody DE
Basic Clin Pharmacol Toxicol; 2011 Jan; 108(1):55-62. PubMed ID: 20825389
[TBL] [Abstract][Full Text] [Related]
6. Metabolism of levo-alpha-Acetylmethadol (LAAM) by human liver cytochrome P450: involvement of CYP3A4 characterized by atypical kinetics with two binding sites.
Oda Y; Kharasch ED
J Pharmacol Exp Ther; 2001 Apr; 297(1):410-22. PubMed ID: 11259570
[TBL] [Abstract][Full Text] [Related]
7. Characterization of dextromethorphan N-demethylation by human liver microsomes. Contribution of the cytochrome P450 3A (CYP3A) subfamily.
Gorski JC; Jones DR; Wrighton SA; Hall SD
Biochem Pharmacol; 1994 Jul; 48(1):173-82. PubMed ID: 8043020
[TBL] [Abstract][Full Text] [Related]
8. Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms.
Renwick AB; Surry D; Price RJ; Lake BG; Evans DC
Xenobiotica; 2000 Oct; 30(10):955-69. PubMed ID: 11315104
[TBL] [Abstract][Full Text] [Related]
9. Contribution of human cytochrome p-450 isoforms to the metabolism of the simplest phenothiazine neuroleptic promazine.
Wójcikowski J; Pichard-Garcia L; Maurel P; Daniel WA
Br J Pharmacol; 2003 Apr; 138(8):1465-74. PubMed ID: 12721102
[TBL] [Abstract][Full Text] [Related]
10. Capillary electrophoresis to assess drug metabolism induced in vitro using single CYP450 enzymes (Supersomes): application to the chiral metabolism of mephenytoin and methadone.
Prost F; Thormann W
Electrophoresis; 2003 Aug; 24(15):2577-87. PubMed ID: 12900870
[TBL] [Abstract][Full Text] [Related]
11. In-vitro characterization of the cytochrome P450 isoenzymes involved in the back oxidation and N-dealkylation of reduced haloperidol.
Pan LP; De Vriendt C; Belpaire FM
Pharmacogenetics; 1998 Oct; 8(5):383-9. PubMed ID: 9825830
[TBL] [Abstract][Full Text] [Related]
12. Identification of three cytochrome P450 isozymes involved in N-demethylation of citalopram enantiomers in human liver microsomes.
Rochat B; Amey M; Gillet M; Meyer UA; Baumann P
Pharmacogenetics; 1997 Feb; 7(1):1-10. PubMed ID: 9110356
[TBL] [Abstract][Full Text] [Related]
13. Identification of cytochrome P450 isoforms involved in citalopram N-demethylation by human liver microsomes.
Kobayashi K; Chiba K; Yagi T; Shimada N; Taniguchi T; Horie T; Tani M; Yamamoto T; Ishizaki T; Kuroiwa Y
J Pharmacol Exp Ther; 1997 Feb; 280(2):927-33. PubMed ID: 9023308
[TBL] [Abstract][Full Text] [Related]
14. Cytochrome P-450 enzymes and FMO3 contribute to the disposition of the antipsychotic drug perazine in vitro.
Störmer E; Brockmöller J; Roots I; Schmider J
Psychopharmacology (Berl); 2000 Sep; 151(4):312-20. PubMed ID: 11026737
[TBL] [Abstract][Full Text] [Related]
15. Comparison of (S)-mephenytoin and proguanil oxidation in vitro: contribution of several CYP isoforms.
Coller JK; Somogyi AA; Bochner F
Br J Clin Pharmacol; 1999 Aug; 48(2):158-67. PubMed ID: 10417492
[TBL] [Abstract][Full Text] [Related]
16. Multiple human cytochromes contribute to biotransformation of dextromethorphan in-vitro: role of CYP2C9, CYP2C19, CYP2D6, and CYP3A.
von Moltke LL; Greenblatt DJ; Grassi JM; Granda BW; Venkatakrishnan K; Schmider J; Harmatz JS; Shader RI
J Pharm Pharmacol; 1998 Sep; 50(9):997-1004. PubMed ID: 9811160
[TBL] [Abstract][Full Text] [Related]
17. Metabolism of 2,5-bis(trifluoromethyl)-7-benzyloxy-4-trifluoromethylcoumarin by human hepatic CYP isoforms: evidence for selectivity towards CYP3A4.
Renwick AB; Lewis DF; Fulford S; Surry D; Williams B; Worboys PD; Cai X; Wang RW; Price RJ; Lake BG; Evans DC
Xenobiotica; 2001 Apr; 31(4):187-204. PubMed ID: 11465405
[TBL] [Abstract][Full Text] [Related]
18. Identification of human liver cytochrome P450 isoforms involved in the in vitro metabolism of cyclobenzaprine.
Wang RW; Liu L; Cheng H
Drug Metab Dispos; 1996 Jul; 24(7):786-91. PubMed ID: 8818577
[TBL] [Abstract][Full Text] [Related]
19. In vitro proguanil activation to cycloguanil is mediated by CYP2C19 and CYP3A4 in adult Chinese liver microsomes.
Lu AH; Shu Y; Huang SL; Wang W; Ou-Yang DS; Zhou HH
Acta Pharmacol Sin; 2000 Aug; 21(8):747-52. PubMed ID: 11501186
[TBL] [Abstract][Full Text] [Related]
20. Characterization of the cytochrome P450 isoenzymes involved in the in vitro N-dealkylation of haloperidol.
Pan LP; Wijnant P; De Vriendt C; Rosseel MT; Belpaire FM
Br J Clin Pharmacol; 1997 Dec; 44(6):557-64. PubMed ID: 9431831
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]