BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

113 related articles for article (PubMed ID: 10235134)

  • 1. Platelets and DAMI megakaryocytes possess beta-secretase-like activity.
    Abraham CR; Marshall DC; Tibbles HE; Otto K; Long HJ; Billingslea AM; Hastey R; Johnson R; Fine RE; Smith SJ; Simons ER; Davies TA
    J Lab Clin Med; 1999 May; 133(5):507-15. PubMed ID: 10235134
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Blood brain barrier endothelial cells express candidate amyloid precursor protein-cleaving secretases.
    Simons ER; Marshall DC; Long HJ; Otto K; Billingslea A; Tibbles H; Wells J; Eisenhauer P; Fine RE; Cribbs DH; Davies TA; Abraham CR
    Amyloid; 1998 Sep; 5(3):153-62. PubMed ID: 9818052
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Stimulus responses and amyloid precursor protein processing in DAMI megakaryocytes.
    Davies TA; Billingslea A; Johnson R; Greenberg S; Ortiz M; Long H; Sgro K; Tibbles H; Seetoo K; Rathbun W; Schonhorn J; Simons ER
    J Lab Clin Med; 1997 Jul; 130(1):21-32. PubMed ID: 9242363
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evaluation of cathepsins D and G and EC 3.4.24.15 as candidate beta-secretase proteases using peptide and amyloid precursor protein substrates.
    Brown AM; Tummolo DM; Spruyt MA; Jacobsen JS; Sonnenberg-Reines J
    J Neurochem; 1996 Jun; 66(6):2436-45. PubMed ID: 8632167
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression and activity of beta-site amyloid precursor protein cleaving enzyme in Alzheimer's disease.
    Johnston JA; Liu WW; Todd SA; Coulson DT; Murphy S; Irvine GB; Passmore AP
    Biochem Soc Trans; 2005 Nov; 33(Pt 5):1096-100. PubMed ID: 16246054
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The 68K protease has beta-secretase-like activity for lymphocyte precursor protein but not for brain substrate.
    Matsumoto A
    Neuroreport; 2000 Feb; 11(2):373-7. PubMed ID: 10674489
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
    J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization.
    Gandhi S; Refolo LM; Sambamurti K
    J Mol Neurosci; 2004; 24(1):137-43. PubMed ID: 15314262
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.
    Vassar R; Bennett BD; Babu-Khan S; Kahn S; Mendiaz EA; Denis P; Teplow DB; Ross S; Amarante P; Loeloff R; Luo Y; Fisher S; Fuller J; Edenson S; Lile J; Jarosinski MA; Biere AL; Curran E; Burgess T; Louis JC; Collins F; Treanor J; Rogers G; Citron M
    Science; 1999 Oct; 286(5440):735-41. PubMed ID: 10531052
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Generation of C-terminally truncated amyloid-beta peptides is dependent on gamma-secretase activity.
    Beher D; Wrigley JD; Owens AP; Shearman MS
    J Neurochem; 2002 Aug; 82(3):563-75. PubMed ID: 12153480
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alzheimer's amyloid precursor protein alpha-secretase is inhibited by hydroxamic acid-based zinc metalloprotease inhibitors: similarities to the angiotensin converting enzyme secretase.
    Parvathy S; Hussain I; Karran EH; Turner AJ; Hooper NM
    Biochemistry; 1998 Feb; 37(6):1680-5. PubMed ID: 9484239
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease.
    Lammich S; Kojro E; Postina R; Gilbert S; Pfeiffer R; Jasionowski M; Haass C; Fahrenholz F
    Proc Natl Acad Sci U S A; 1999 Mar; 96(7):3922-7. PubMed ID: 10097139
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from gamma-secretase.
    Nunan J; Shearman MS; Checler F; Cappai R; Evin G; Beyreuther K; Masters CL; Small DH
    Eur J Biochem; 2001 Oct; 268(20):5329-36. PubMed ID: 11606195
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Distinct secretases, a cysteine protease and a serine protease, generate the C termini of amyloid beta-proteins Abeta1-40 and Abeta1-42, respectively.
    Figueiredo-Pereira ME; Efthimiopoulos S; Tezapsidis N; Buku A; Ghiso J; Mehta P; Robakis NK
    J Neurochem; 1999 Apr; 72(4):1417-22. PubMed ID: 10098844
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cleavage of Alzheimer's amyloid precursor protein by alpha-secretase occurs at the surface of neuronal cells.
    Parvathy S; Hussain I; Karran EH; Turner AJ; Hooper NM
    Biochemistry; 1999 Jul; 38(30):9728-34. PubMed ID: 10423252
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cathepsin D displays in vitro beta-secretase-like specificity.
    Chevallier N; Vizzavona J; Marambaud P; Baur CP; Spillantini M; Fulcrand P; Martinez J; Goedert M; Vincent JP; Checler F
    Brain Res; 1997 Mar; 750(1-2):11-9. PubMed ID: 9098524
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Beta-amyloid peptide in regulated secretory vesicles of chromaffin cells: evidence for multiple cysteine proteolytic activities in distinct pathways for beta-secretase activity in chromaffin vesicles.
    Hook VY; Toneff T; Aaron W; Yasothornsrikul S; Bundey R; Reisine T
    J Neurochem; 2002 Apr; 81(2):237-56. PubMed ID: 12064471
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Gelatinase A possesses a beta-secretase-like activity in cleaving the amyloid protein precursor of Alzheimer's disease.
    LePage RN; Fosang AJ; Fuller SJ; Murphy G; Evin G; Beyreuther K; Masters CL; Small DH
    FEBS Lett; 1995 Dec; 377(2):267-70. PubMed ID: 8543065
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Specific Inhibition of β-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein.
    Ben Halima S; Mishra S; Raja KMP; Willem M; Baici A; Simons K; Brüstle O; Koch P; Haass C; Caflisch A; Rajendran L
    Cell Rep; 2016 Mar; 14(9):2127-2141. PubMed ID: 26923602
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.