222 related articles for article (PubMed ID: 10318942)
1. Defining therapeutic targets by using adenovirus: blocking NF-kappaB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators.
Bondeson J; Foxwell B; Brennan F; Feldmann M
Proc Natl Acad Sci U S A; 1999 May; 96(10):5668-73. PubMed ID: 10318942
[TBL] [Abstract][Full Text] [Related]
2. Adenoviral gene transfer into osteoarthritis synovial cells using the endogenous inhibitor IkappaBalpha reveals that most, but not all, inflammatory and destructive mediators are NFkappaB dependent.
Amos N; Lauder S; Evans A; Feldmann M; Bondeson J
Rheumatology (Oxford); 2006 Oct; 45(10):1201-9. PubMed ID: 16571608
[TBL] [Abstract][Full Text] [Related]
3. Evidence that rheumatoid arthritis synovial T cells are similar to cytokine-activated T cells: involvement of phosphatidylinositol 3-kinase and nuclear factor kappaB pathways in tumor necrosis factor alpha production in rheumatoid arthritis.
Brennan FM; Hayes AL; Ciesielski CJ; Green P; Foxwell BM; Feldmann M
Arthritis Rheum; 2002 Jan; 46(1):31-41. PubMed ID: 11822409
[TBL] [Abstract][Full Text] [Related]
4. Adenoviral gene transfer of the endogenous inhibitor IkappaBalpha into human osteoarthritis synovial fibroblasts demonstrates that several matrix metalloproteinases and aggrecanases are nuclear factor-kappaB-dependent.
Bondeson J; Lauder S; Wainwright S; Amos N; Evans A; Hughes C; Feldmann M; Caterson B
J Rheumatol; 2007 Mar; 34(3):523-33. PubMed ID: 17295438
[TBL] [Abstract][Full Text] [Related]
5. Efficient adenoviral infection with IkappaB alpha reveals that macrophage tumor necrosis factor alpha production in rheumatoid arthritis is NF-kappaB dependent.
Foxwell B; Browne K; Bondeson J; Clarke C; de Martin R; Brennan F; Feldmann M
Proc Natl Acad Sci U S A; 1998 Jul; 95(14):8211-5. PubMed ID: 9653166
[TBL] [Abstract][Full Text] [Related]
6. Regulation of IL-6 and IL-8 expression in rheumatoid arthritis synovial fibroblasts: the dominant role for NF-kappa B but not C/EBP beta or c-Jun.
Georganas C; Liu H; Perlman H; Hoffmann A; Thimmapaya B; Pope RM
J Immunol; 2000 Dec; 165(12):7199-206. PubMed ID: 11120852
[TBL] [Abstract][Full Text] [Related]
7. Effective adenoviral transfer of IkappaBalpha into human fibroblasts and chondrosarcoma cells reveals that the induction of matrix metalloproteinases and proinflammatory cytokines is nuclear factor-kappaB dependent.
Bondeson J; Brennan F; Foxwell B; Feldmann M
J Rheumatol; 2000 Sep; 27(9):2078-89. PubMed ID: 10990217
[TBL] [Abstract][Full Text] [Related]
8. Responses to the proinflammatory cytokines interleukin-1 and tumor necrosis factor alpha in cells derived from rheumatoid synovium and other joint tissues involve nuclear factor kappaB-mediated induction of the Ets transcription factor ESE-1.
Grall F; Gu X; Tan L; Cho JY; Inan MS; Pettit AR; Thamrongsak U; Choy BK; Manning C; Akbarali Y; Zerbini L; Rudders S; Goldring SR; Gravallese EM; Oettgen P; Goldring MB; Libermann TA
Arthritis Rheum; 2003 May; 48(5):1249-60. PubMed ID: 12746898
[TBL] [Abstract][Full Text] [Related]
9. Selective regulation of cytokine induction by adenoviral gene transfer of IkappaBalpha into human macrophages: lipopolysaccharide-induced, but not zymosan-induced, proinflammatory cytokines are inhibited, but IL-10 is nuclear factor-kappaB independent.
Bondeson J; Browne KA; Brennan FM; Foxwell BM; Feldmann M
J Immunol; 1999 Mar; 162(5):2939-45. PubMed ID: 10072544
[TBL] [Abstract][Full Text] [Related]
10. Heterogeneous requirement of IkappaB kinase 2 for inflammatory cytokine and matrix metalloproteinase production in rheumatoid arthritis: implications for therapy.
Andreakos E; Smith C; Kiriakidis S; Monaco C; de Martin R; Brennan FM; Paleolog E; Feldmann M; Foxwell BM
Arthritis Rheum; 2003 Jul; 48(7):1901-12. PubMed ID: 12847684
[TBL] [Abstract][Full Text] [Related]
11. 15-deoxy-Δ(12,14) -prostaglandin-J2 and ciglitazone inhibit TNF-α-induced matrix metalloproteinase 13 production via the antagonism of NF-κB activation in human synovial fibroblasts.
Lin TH; Tang CH; Wu K; Fong YC; Yang RS; Fu WM
J Cell Physiol; 2011 Dec; 226(12):3242-50. PubMed ID: 21344384
[TBL] [Abstract][Full Text] [Related]
12. Glucocorticoid-mediated repression of inflammatory cytokine production in fibroblast-like rheumatoid synoviocytes is independent of nuclear factor-kappaB activation induced by tumour necrosis factor alpha.
Han CW; Choi JH; Kim JM; Kim WY; Lee KY; Oh GT
Rheumatology (Oxford); 2001 Mar; 40(3):267-73. PubMed ID: 11285373
[TBL] [Abstract][Full Text] [Related]
13. A pro-inflammatory role for A20 and ABIN family proteins in human fibroblast-like synoviocytes in rheumatoid arthritis.
Igarashi H; Yahagi A; Saika T; Hashimoto J; Tomita T; Yoshikawa H; Ishihara K
Immunol Lett; 2012 Jan; 141(2):246-53. PubMed ID: 22093807
[TBL] [Abstract][Full Text] [Related]
14. Overexpression of sirtuin 6 suppresses inflammatory responses and bone destruction in mice with collagen-induced arthritis.
Lee HS; Ka SO; Lee SM; Lee SI; Park JW; Park BH
Arthritis Rheum; 2013 Jul; 65(7):1776-85. PubMed ID: 23553536
[TBL] [Abstract][Full Text] [Related]
15. The suppressive effects of Saposhnikovia divaricata (Fangfeng) chromone extract on rheumatoid arthritis via inhibition of nuclear factor-κB and mitogen activated proteinkinases activation on collagen-induced arthritis model.
Kong X; Liu C; Zhang C; Zhao J; Wang J; Wan H; Zhu H; Zhang P; Chen W; Xiao Y; Lin N
J Ethnopharmacol; 2013 Jul; 148(3):842-50. PubMed ID: 23711830
[TBL] [Abstract][Full Text] [Related]
16. Anti-inflammatory effect of adenovirus-mediated IkappaBalpha overexpression in respiratory epithelial cells.
Park GY; Le S; Park KH; Le CT; Kim YW; Han SK; Shim YS; Yoo CG
Eur Respir J; 2001 Nov; 18(5):801-9. PubMed ID: 11757631
[TBL] [Abstract][Full Text] [Related]
17. The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis.
Bondeson J; Wainwright SD; Lauder S; Amos N; Hughes CE
Arthritis Res Ther; 2006; 8(6):R187. PubMed ID: 17177994
[TBL] [Abstract][Full Text] [Related]
18. Bromodomain and extra-terminal domain bromodomain inhibition prevents synovial inflammation via blocking IκB kinase-dependent NF-κB activation in rheumatoid fibroblast-like synoviocytes.
Xiao Y; Liang L; Huang M; Qiu Q; Zeng S; Shi M; Zou Y; Ye Y; Yang X; Xu H
Rheumatology (Oxford); 2016 Jan; 55(1):173-84. PubMed ID: 26324948
[TBL] [Abstract][Full Text] [Related]
19. Is NF-kappaB a useful therapeutic target in rheumatoid arthritis?
Feldmann M; Andreakos E; Smith C; Bondeson J; Yoshimura S; Kiriakidis S; Monaco C; Gasparini C; Sacre S; Lundberg A; Paleolog E; Horwood NJ; Brennan FM; Foxwell BM
Ann Rheum Dis; 2002 Nov; 61 Suppl 2(Suppl 2):ii13-8. PubMed ID: 12379614
[TBL] [Abstract][Full Text] [Related]
20. Reduction of tumor necrosis factor induced nuclear factor-kappaB nuclear translocation and DNA binding by dexamethasone in human osteoarthritic synovial tissue explants.
Lehmann T; Murphy C; Zahra DG; Handel ML
J Rheumatol; 2002 Apr; 29(4):787-95. PubMed ID: 11950023
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
