129 related articles for article (PubMed ID: 10327036)
1. Comparative activity of the cyclopropylpyrroloindole compounds adozelesin, bizelesin and carzelesin in a human tumor colony-forming assay.
Hidalgo M; Izbicka E; Cerna C; Gomez L; Rowinsky EK; Weitman SD; Von Hoff DD
Anticancer Drugs; 1999 Mar; 10(3):295-302. PubMed ID: 10327036
[TBL] [Abstract][Full Text] [Related]
2. The DNA minor groove-alkylating cyclopropylpyrroloindole drugs adozelesin and bizelesin induce different DNA damage response pathways in human colon carcinoma HCT116 cells.
Cao PR; McHugh MM; Melendy T; Beerman T
Mol Cancer Ther; 2003 Jul; 2(7):651-9. PubMed ID: 12883038
[TBL] [Abstract][Full Text] [Related]
3. Cytotoxicity and antitumor activity of carzelesin, a prodrug cyclopropylpyrroloindole analogue.
Li LH; DeKoning TF; Kelly RC; Krueger WC; McGovren JP; Padbury GE; Petzold GL; Wallace TL; Ouding RJ; Prairie MD
Cancer Res; 1992 Sep; 52(18):4904-13. PubMed ID: 1516047
[TBL] [Abstract][Full Text] [Related]
4. Mapping of DNA alkylation sites induced by adozelesin and bizelesin in human cells by ligation-mediated polymerase chain reaction.
Lee CS; Pfeifer GP; Gibson NW
Biochemistry; 1994 May; 33(19):6024-30. PubMed ID: 8180230
[TBL] [Abstract][Full Text] [Related]
5. Region-specific DNA damage by AT-specific DNA-reactive drugs is predicted by drug binding specificity.
Woynarowski JM; Napier C; Trevino AV; Arnett B
Biochemistry; 2000 Aug; 39(32):9917-27. PubMed ID: 10933811
[TBL] [Abstract][Full Text] [Related]
6. Sequence selectivity of DNA alkylation by adozelesin and carzelesin.
Yoon JH; Lee CS
Arch Pharm Res; 1998 Aug; 21(4):385-90. PubMed ID: 9875464
[TBL] [Abstract][Full Text] [Related]
7. Preclinical pharmacology of bizelesin, a potent bifunctional analog of the DNA-binding antibiotic CC-1065.
Walker DL; Reid JM; Ames MM
Cancer Chemother Pharmacol; 1994; 34(4):317-22. PubMed ID: 8033298
[TBL] [Abstract][Full Text] [Related]
8. Antitumor activity of MGI 114 (6-hydroxymethylacylfulvene, HMAF), a semisynthetic derivative of illudin S, against adult and pediatric human tumor colony-forming units.
Hidalgo M; Izbicka E; Eckhardt SG; MacDonald JR; Cerna C; Gomez L; Rowinsky EK; Weitman SD; Von Hoff DD
Anticancer Drugs; 1999 Oct; 10(9):837-44. PubMed ID: 10587294
[TBL] [Abstract][Full Text] [Related]
9. Adozelesin, a selected lead among cyclopropylpyrroloindole analogs of the DNA-binding antibiotic, CC-1065.
Li LH; Kelly RC; Warpehoski MA; McGovren JP; Gebhard I; DeKoning TF
Invest New Drugs; 1991 May; 9(2):137-48. PubMed ID: 1874598
[TBL] [Abstract][Full Text] [Related]
10. Recent developments in sequence selective minor groove DNA effectors.
Reddy BS; Sharma SK; Lown JW
Curr Med Chem; 2001 Apr; 8(5):475-508. PubMed ID: 11281837
[TBL] [Abstract][Full Text] [Related]
11. Synergistic and additive combinations of several antitumor drugs and other agents with the potent alkylating agent adozelesin.
Smith KS; Folz BA; Adams EG; Bhuyan BK
Cancer Chemother Pharmacol; 1995; 35(6):471-82. PubMed ID: 7533669
[TBL] [Abstract][Full Text] [Related]
12. Determination of the structural role of the linking moieties in the DNA binding of adozelesin.
Cameron L; Thompson AS
Biochemistry; 2000 May; 39(17):5004-12. PubMed ID: 10819964
[TBL] [Abstract][Full Text] [Related]
13. Comparative pharmacology of the novel cyclopropylpyrroloindole-prodrug carzelesin in mice, rats, and humans.
van Tellingen O; Nooijen WJ; Schaaf LJ; van der Valk M; van Asperen J; Henrar RE; Beijnen JH
Cancer Res; 1998 Jun; 58(11):2410-6. PubMed ID: 9622082
[TBL] [Abstract][Full Text] [Related]
14. Evaluation of the antineoplastic activity of adozelesin alone and in combination with 5-aza-2'-deoxycytidine and cytosine arabinoside on DLD-1 human colon carcinoma cells.
Côté S; Momparler RL
Anticancer Drugs; 1993 Jun; 4(3):327-33. PubMed ID: 7689364
[TBL] [Abstract][Full Text] [Related]
15. Phase I trial of Adozelesin using the treatment schedule of daily x5 every 3 weeks.
Foster BJ; LoRusso PM; Poplin E; Zalupski M; Valdivieso M; Wozniak A; Flaherty L; Kasunic DA; Earhart RH; Baker LH
Invest New Drugs; 1996; 13(4):321-6. PubMed ID: 8824350
[TBL] [Abstract][Full Text] [Related]
16. Therapeutic efficacy of the cyclopropylpyrroloindole, carzelesin, against xenografts derived from adult and childhood solid tumors.
Houghton PJ; Cheshire PJ; Hallman JD; Houghton JA
Cancer Chemother Pharmacol; 1995; 36(1):45-52. PubMed ID: 7720175
[TBL] [Abstract][Full Text] [Related]
17. Does the antitumor cyclopropylpyrroloindole antibiotic CC-1065 cross-link DNA in tumor cells?
Skladanowski A; Koba M; Konopa J
Biochem Pharmacol; 2001 Jan; 61(1):67-72. PubMed ID: 11137711
[TBL] [Abstract][Full Text] [Related]
18. Myelotoxic effects of the bifunctional alkylating agent bizelesin on human, canine and murine myeloid progenitor cells.
Volpe DA; Tomaszewski JE; Parchment RE; Garg A; Flora KP; Murphy MJ; Grieshaber CK
Cancer Chemother Pharmacol; 1996; 39(1-2):143-9. PubMed ID: 8995512
[TBL] [Abstract][Full Text] [Related]
19. Adozelesin triggers DNA damage response pathways and arrests SV40 DNA replication through replication protein A inactivation.
Liu JS; Kuo SR; McHugh MM; Beerman TA; Melendy T
J Biol Chem; 2000 Jan; 275(2):1391-7. PubMed ID: 10625690
[TBL] [Abstract][Full Text] [Related]
20. Preclinical antitumor activity of bizelesin in mice.
Carter CA; Waud WR; Li LH; DeKoning TF; McGovren JP; Plowman J
Clin Cancer Res; 1996 Jul; 2(7):1143-9. PubMed ID: 9816280
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
