BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 10329458)

  • 1. Dihydropteroate synthase from Streptococcus pneumoniae: characterization of substrate binding order and sulfonamide inhibition.
    Vinnicombe HG; Derrick JP
    Biochem Biophys Res Commun; 1999 May; 258(3):752-7. PubMed ID: 10329458
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dihydropteroate synthase from Streptococcus pneumoniae: structure, ligand recognition and mechanism of sulfonamide resistance.
    Levy C; Minnis D; Derrick JP
    Biochem J; 2008 Jun; 412(2):379-88. PubMed ID: 18321242
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structure of Mycobacterium tuberculosis 7,8-dihydropteroate synthase in complex with pterin monophosphate: new insight into the enzymatic mechanism and sulfa-drug action.
    Baca AM; Sirawaraporn R; Turley S; Sirawaraporn W; Hol WG
    J Mol Biol; 2000 Oct; 302(5):1193-212. PubMed ID: 11007651
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Amino acid repetitions in the dihydropteroate synthase of Streptococcus pneumoniae lead to sulfonamide resistance with limited effects on substrate K(m).
    Haasum Y; Ström K; Wehelie R; Luna V; Roberts MC; Maskell JP; Hall LM; Swedberg G
    Antimicrob Agents Chemother; 2001 Mar; 45(3):805-9. PubMed ID: 11181365
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase.
    Dennis ML; Lee MD; Harjani JR; Ahmed M; DeBono AJ; Pitcher NP; Wang ZC; Chhabra S; Barlow N; Rahmani R; Cleary B; Dolezal O; Hattarki M; Aurelio L; Shonberg J; Graham B; Peat TS; Baell JB; Swarbrick JD
    Chemistry; 2018 Feb; 24(8):1922-1930. PubMed ID: 29171692
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Biochemical and structural characterization of the putative dihydropteroate synthase ortholog Rv1207 of Mycobacterium tuberculosis.
    Gengenbacher M; Xu T; Niyomrattanakit P; Spraggon G; Dick T
    FEMS Microbiol Lett; 2008 Oct; 287(1):128-35. PubMed ID: 18680522
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Exploring the catalytic mechanism of dihydropteroate synthase: elucidating the differences between the substrate and inhibitor.
    Chotpatiwetchkul W; Boonyarattanakalin K; Gleeson D; Gleeson MP
    Org Biomol Chem; 2017 Jul; 15(26):5593-5601. PubMed ID: 28639657
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystal structure of 7,8-dihydropteroate synthase from Bacillus anthracis: mechanism and novel inhibitor design.
    Babaoglu K; Qi J; Lee RE; White SW
    Structure; 2004 Sep; 12(9):1705-17. PubMed ID: 15341734
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Arabidopsis dihydropteroate synthase: general properties and inhibition by reaction product and sulfonamides.
    Prabhu V; Lui H; King J
    Phytochemistry; 1997 May; 45(1):23-7. PubMed ID: 9127492
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A rapid assay for dihydropteroate synthase activity suitable for identification of inhibitors.
    Fernley RT; Iliades P; Macreadie I
    Anal Biochem; 2007 Jan; 360(2):227-34. PubMed ID: 17134675
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A proof-of-concept receptor-based assay for sulfonamides.
    Liang X; Wang Z; Wang C; Wen K; Mi T; Zhang J; Zhang S
    Anal Biochem; 2013 Jul; 438(2):110-6. PubMed ID: 23567760
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase.
    Achari A; Somers DO; Champness JN; Bryant PK; Rosemond J; Stammers DK
    Nat Struct Biol; 1997 Jun; 4(6):490-7. PubMed ID: 9187658
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-based design of a potent and selective small peptide inhibitor of Mycobacterium tuberculosis 6-hydroxymethyl-7, 8-dihydropteroate synthase: a computer modelling approach.
    Rao GS; Kumar M
    Chem Biol Drug Des; 2008 Jun; 71(6):540-5. PubMed ID: 18482337
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition studies of sulfonamide-containing folate analogs in yeast.
    Patel O; Satchell J; Baell J; Fernley R; Coloe P; Macreadie I
    Microb Drug Resist; 2003; 9(2):139-46. PubMed ID: 12820798
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kinetic and structural characterization of a product complex of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Escherichia coli.
    Garçon A; Bermingham A; Lian LY; Derrick JP
    Biochem J; 2004 Jun; 380(Pt 3):867-73. PubMed ID: 15018613
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sulfonamide resistance in Streptococcus pneumoniae: DNA sequence of the gene encoding dihydropteroate synthase and characterization of the enzyme.
    Lopez P; Espinosa M; Greenberg B; Lacks SA
    J Bacteriol; 1987 Sep; 169(9):4320-6. PubMed ID: 3114239
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Folate synthesis in higher-plant mitochondria: coupling between the dihydropterin pyrophosphokinase and the dihydropteroate synthase activities.
    Mouillon JM; Ravanel S; Douce R; Rébeillé F
    Biochem J; 2002 Apr; 363(Pt 2):313-9. PubMed ID: 11931659
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The three-dimensional structure of the bifunctional 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase/dihydropteroate synthase of Saccharomyces cerevisiae.
    Lawrence MC; Iliades P; Fernley RT; Berglez J; Pilling PA; Macreadie IG
    J Mol Biol; 2005 May; 348(3):655-70. PubMed ID: 15826662
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pterin-sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents.
    Zhao Y; Shadrick WR; Wallace MJ; Wu Y; Griffith EC; Qi J; Yun MK; White SW; Lee RE
    Bioorg Med Chem Lett; 2016 Aug; 26(16):3950-4. PubMed ID: 27423480
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Elucidation of sulfadoxine resistance with structural models of the bifunctional Plasmodium falciparum dihydropterin pyrophosphokinase-dihydropteroate synthase.
    de Beer TA; Louw AI; Joubert F
    Bioorg Med Chem; 2006 Jul; 14(13):4433-43. PubMed ID: 16517168
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.