BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

63 related articles for article (PubMed ID: 10331859)

  • 1. How the regulatory and catalytic domains get together.
    Vrana KE
    Nat Struct Biol; 1999 May; 6(5):401-2. PubMed ID: 10331859
    [No Abstract]   [Full Text] [Related]  

  • 2. Structural basis of autoregulation of phenylalanine hydroxylase.
    Kobe B; Jennings IG; House CM; Michell BJ; Goodwill KE; Santarsiero BD; Stevens RC; Cotton RG; Kemp BE
    Nat Struct Biol; 1999 May; 6(5):442-8. PubMed ID: 10331871
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Conformational selection turns on phenylalanine hydroxylase.
    Konovalov KA; Wang W; Huang X
    J Biol Chem; 2018 Dec; 293(51):19544-19545. PubMed ID: 30578407
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of phenylalanine hydroxylase: conformational changes upon phenylalanine binding detected by hydrogen/deuterium exchange and mass spectrometry.
    Li J; Dangott LJ; Fitzpatrick PF
    Biochemistry; 2010 Apr; 49(15):3327-35. PubMed ID: 20307070
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Towards the identification of the allosteric Phe-binding site in phenylalanine hydroxylase.
    Carluccio C; Fraternali F; Salvatore F; Fornili A; Zagari A
    J Biomol Struct Dyn; 2016; 34(3):497-507. PubMed ID: 26479306
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Searching distant homologs of the regulatory ACT domain in phenylalanine hydroxylase.
    Siltberg-Liberles J; Martinez A
    Amino Acids; 2009 Feb; 36(2):235-49. PubMed ID: 18368466
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphorylation of Phenylalanine Hydroxylase Increases the Rate Constant for Formation of the Activated Conformation of the Enzyme.
    Khan CA; Fitzpatrick PF
    Biochemistry; 2018 Nov; 57(44):6274-6277. PubMed ID: 30346142
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of phenylalanine hydroxylase: effect of substitutions at Arg68 and Cys237.
    Thórólfsson M; Teigen K; Martínez A
    Biochemistry; 2003 Apr; 42(12):3419-28. PubMed ID: 12653545
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Allosteric regulation of phenylalanine hydroxylase.
    Fitzpatrick PF
    Arch Biochem Biophys; 2012 Mar; 519(2):194-201. PubMed ID: 22005392
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of the Allosteric Site for Phenylalanine in Rat Phenylalanine Hydroxylase.
    Zhang S; Fitzpatrick PF
    J Biol Chem; 2016 Apr; 291(14):7418-25. PubMed ID: 26823465
    [TBL] [Abstract][Full Text] [Related]  

  • 11. High resolution crystal structures of the catalytic domain of human phenylalanine hydroxylase in its catalytically active Fe(II) form and binary complex with tetrahydrobiopterin.
    Andersen OA; Flatmark T; Hough E
    J Mol Biol; 2001 Nov; 314(2):279-91. PubMed ID: 11718561
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Amino Acid Specificity for Activation of Phenylalanine Hydroxylase Matches the Specificity for Stabilization of Regulatory Domain Dimers.
    Zhang S; Hinck AP; Fitzpatrick PF
    Biochemistry; 2015 Aug; 54(33):5167-74. PubMed ID: 26252467
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crosstalk between the catalytic and regulatory domains allows bidirectional regulation of Src.
    Gonfloni S; Weijland A; Kretzschmar J; Superti-Furga G
    Nat Struct Biol; 2000 Apr; 7(4):281-6. PubMed ID: 10742171
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human phenylalanine hydroxylase is activated by H2O2: a novel mechanism for increasing the L-tyrosine supply for melanogenesis in melanocytes.
    Schallreuter KU; Wazir U; Kothari S; Gibbons NC; Moore J; Wood JM
    Biochem Biophys Res Commun; 2004 Sep; 322(1):88-92. PubMed ID: 15313177
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural and stability effects of phosphorylation: Localized structural changes in phenylalanine hydroxylase.
    Miranda FF; Thórólfsson M; Teigen K; Sanchez-Ruiz JM; Martínez A
    Protein Sci; 2004 May; 13(5):1219-26. PubMed ID: 15096628
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Direct evidence for a phenylalanine site in the regulatory domain of phenylalanine hydroxylase.
    Li J; Ilangovan U; Daubner SC; Hinck AP; Fitzpatrick PF
    Arch Biochem Biophys; 2011 Jan; 505(2):250-5. PubMed ID: 20951114
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vitro expression of 34 naturally occurring mutant variants of phenylalanine hydroxylase: correlation with metabolic phenotypes and susceptibility toward protein aggregation.
    Gjetting T; Petersen M; Guldberg P; Güttler F
    Mol Genet Metab; 2001 Feb; 72(2):132-43. PubMed ID: 11161839
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The structural basis of allosteric regulation in proteins.
    Laskowski RA; Gerick F; Thornton JM
    FEBS Lett; 2009 Jun; 583(11):1692-8. PubMed ID: 19303011
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Domain Movements upon Activation of Phenylalanine Hydroxylase Characterized by Crystallography and Chromatography-Coupled Small-Angle X-ray Scattering.
    Meisburger SP; Taylor AB; Khan CA; Zhang S; Fitzpatrick PF; Ando N
    J Am Chem Soc; 2016 May; 138(20):6506-16. PubMed ID: 27145334
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dynamic regulation of phenylalanine hydroxylase by simulated redox manipulation.
    Fuchs JE; Huber RG; von Grafenstein S; Wallnoefer HG; Spitzer GM; Fuchs D; Liedl KR
    PLoS One; 2012; 7(12):e53005. PubMed ID: 23300845
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.