189 related articles for article (PubMed ID: 10333389)
1. Lanosterol analogs: dual-action inhibitors of cholesterol biosynthesis.
Frye LL; Leonard DA
Crit Rev Biochem Mol Biol; 1999; 34(2):123-40. PubMed ID: 10333389
[TBL] [Abstract][Full Text] [Related]
2. Oxolanosterol oximes: dual-action inhibitors of cholesterol biosynthesis.
Frye LL; Cusack KP; Leonard DA; Anderson JA
J Lipid Res; 1994 Aug; 35(8):1333-44. PubMed ID: 7989858
[TBL] [Abstract][Full Text] [Related]
3. 32-Methyl-32-oxylanosterols: dual-action inhibitors of cholesterol biosynthesis.
Frye LL; Cusack KP; Leonard DA
J Med Chem; 1993 Feb; 36(3):410-6. PubMed ID: 8426367
[TBL] [Abstract][Full Text] [Related]
4. 15-substituted lanosterols: post-transcriptional suppressors of 3-hydroxy-3-methylglutaryl coenzyme A reductase.
Anderson JA; Leonard DA; Cusack KP; Frye LL
Arch Biochem Biophys; 1995 Jan; 316(1):190-6. PubMed ID: 7840615
[TBL] [Abstract][Full Text] [Related]
5. Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by 3 beta-hydroxy-lanost-8-en-32-al, an intermediate in the conversion of lanosterol to cholesterol.
Leonard DA; Kotarski MA; Tessiatore JE; Favata MF; Trzaskos JM
Arch Biochem Biophys; 1994 Apr; 310(1):152-7. PubMed ID: 8161198
[TBL] [Abstract][Full Text] [Related]
6. Modulation of 3-hydroxy-3-methylglutaryl-CoA reductase by 15 alpha-fluorolanost-7-en-3 beta-ol. A mechanism-based inhibitor of cholesterol biosynthesis.
Trzaskos JM; Magolda RL; Favata MF; Fischer RT; Johnson PR; Chen HW; Ko SS; Leonard DA; Gaylor JL
J Biol Chem; 1993 Oct; 268(30):22591-9. PubMed ID: 7693673
[TBL] [Abstract][Full Text] [Related]
7. Effects of a novel lanosterol 14 alpha-demethylase inhibitor on the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in Hep G2 cells.
Mayer RJ; Adams JL; Bossard MJ; Berkhout TA
J Biol Chem; 1991 Oct; 266(30):20070-8. PubMed ID: 1657912
[TBL] [Abstract][Full Text] [Related]
8. Substrate-based inhibitors of lanosterol 14 alpha-methyl demethylase: I. Assessment of inhibitor structure-activity relationship and cholesterol biosynthesis inhibition properties.
Trzaskos JM; Ko SS; Magolda RL; Favata MF; Fischer RT; Stam SH; Johnson PR; Gaylor JL
Biochemistry; 1995 Aug; 34(30):9670-6. PubMed ID: 7626636
[TBL] [Abstract][Full Text] [Related]
9. Effects of 19-oxygenated lanosterol derivatives on 3-hydroxy-3-methylglutaryl coenzyme a reductase activity and lanosterol demethylase activity.
Sonoda Y; Suzuki S; Udagawa K; Ota K; Tasaka R; Fukamachi Y; Sato Y
Biol Pharm Bull; 1996 Jan; 19(1):57-61. PubMed ID: 8820912
[TBL] [Abstract][Full Text] [Related]
10. Azalanstat (RS-21607), a lanosterol 14 alpha-demethylase inhibitor with cholesterol-lowering activity.
Burton PM; Swinney DC; Heller R; Dunlap B; Chiou M; Malonzo E; Haller J; Walker KA; Salari A; Murakami S
Biochem Pharmacol; 1995 Aug; 50(4):529-44. PubMed ID: 7646560
[TBL] [Abstract][Full Text] [Related]
11. Apomine, a novel hypocholesterolemic agent, accelerates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and stimulates low density lipoprotein receptor activity.
Roitelman J; Masson D; Avner R; Ammon-Zufferey C; Perez A; Guyon-Gellin Y; Bentzen CL; Niesor EJ
J Biol Chem; 2004 Feb; 279(8):6465-73. PubMed ID: 14627708
[TBL] [Abstract][Full Text] [Related]
12. Cholesterol biosynthesis from lanosterol: development of a novel assay method and characterization of rat liver microsomal lanosterol delta 24-reductase.
Bae SH; Paik YK
Biochem J; 1997 Sep; 326 ( Pt 2)(Pt 2):609-16. PubMed ID: 9291139
[TBL] [Abstract][Full Text] [Related]
13. Effects of 15-oxa-32-vinyl-lanost-8-ene-3 beta,32 diol on the expression of 3-hydroxy-3-methylglutaryl coenzyme A reductase and low density lipoprotein receptor in rat liver.
Ness GC; Lopez D; Chambers CM; Zhao Z; Beach DL; Ko SS; Trzaskos JM
Arch Biochem Biophys; 1998 Sep; 357(2):259-64. PubMed ID: 9735166
[TBL] [Abstract][Full Text] [Related]
14. Down-regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase mRNA levels and synthesis in syrian hamster C100 cells by the oxidosqualene cyclase inhibitor [4'-(6-allyl-ethyl-amino-hexyloxy)-2'-fluoro-phenyl]-(4-bromophenyl)-me thanone (Ro 48-8071): comparison to simvastatin.
Peffley DM; Gayen AK; Morand OH
Biochem Pharmacol; 1998 Aug; 56(4):439-49. PubMed ID: 9763219
[TBL] [Abstract][Full Text] [Related]
15. Dual-action hypoglycemic and hypocholesterolemic agents that inhibit glycogen phosphorylase and lanosterol demethylase.
Harwood HJ; Petras SF; Hoover DJ; Mankowski DC; Soliman VF; Sugarman ED; Hulin B; Kwon Y; Gibbs EM; Mayne JT; Treadway JL
J Lipid Res; 2005 Mar; 46(3):547-63. PubMed ID: 15604516
[TBL] [Abstract][Full Text] [Related]
16. Selective inhibition of mammalian lanosterol 14 alpha-demethylase by RS-21607 in vitro and in vivo.
Swinney DC; So OY; Watson DM; Berry PW; Webb AS; Kertesz DJ; Shelton EJ; Burton PM; Walker KA
Biochemistry; 1994 Apr; 33(15):4702-13. PubMed ID: 8161528
[TBL] [Abstract][Full Text] [Related]
17. In situ accumulation of 3 beta-hydroxylanost-8-en-32-aldehyde in hepatocyte cultures. A putative regulator of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity.
Trzaskos JM; Favata MF; Fischer RT; Stam SH
J Biol Chem; 1987 Sep; 262(25):12261-8. PubMed ID: 3624256
[TBL] [Abstract][Full Text] [Related]
18. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesterol biosynthesis by oxylanosterols.
Panini SR; Sexton RC; Gupta AK; Parish EJ; Chitrakorn S; Rudney H
J Lipid Res; 1986 Nov; 27(11):1190-204. PubMed ID: 3559385
[TBL] [Abstract][Full Text] [Related]
19. Modulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase by azole antimycotics requires lanosterol demethylation, but not 24,25-epoxylanosterol formation.
Favata MF; Trzaskos JM; Chen HW; Fischer RT; Greenberg RS
J Biol Chem; 1987 Sep; 262(25):12254-60. PubMed ID: 3624255
[TBL] [Abstract][Full Text] [Related]
20. Effect of 26-oxygenosterols from Ganoderma lucidum and their activity as cholesterol synthesis inhibitors.
Hajjaj H; Macé C; Roberts M; Niederberger P; Fay LB
Appl Environ Microbiol; 2005 Jul; 71(7):3653-8. PubMed ID: 16000773
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]