285 related articles for article (PubMed ID: 10338365)
1. Synthesis, characterization and preclinical formulation of a dual-action phenyl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07) with potent anti-HIV and spermicidal activities.
D'Cruz OJ; Shih MJ; Yiv SH; Chen CL; Uckun FM
Mol Hum Reprod; 1999 May; 5(5):421-32. PubMed ID: 10338365
[TBL] [Abstract][Full Text] [Related]
2. WHI-05, a novel bromo-methoxy substituted phenyl phosphate derivative of zidovudine, is a dual-action spermicide with potent anti-HIV activity.
D'Cruz OJ; Zhu Z; Yiv SH; Chen CL; Waurzyniak B; Uckun FM
Contraception; 1999 May; 59(5):319-31. PubMed ID: 10494486
[TBL] [Abstract][Full Text] [Related]
3. Aryl phosphate derivatives of bromo-methoxy-azidothymidine are dual-function spermicides with potent anti-human immunodeficiency virus.
D'Cruz OJ; Venkatachalam TK; Zhu Z; Shih MJ; Uckun FM
Biol Reprod; 1998 Sep; 59(3):503-15. PubMed ID: 9716547
[TBL] [Abstract][Full Text] [Related]
4. Structural requirements for potent human spermicidal activity of dual-function aryl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07).
D'Cruz OJ; Venkatachalam TK; Uckun FM
Biol Reprod; 2000 Jan; 62(1):37-44. PubMed ID: 10611065
[TBL] [Abstract][Full Text] [Related]
5. Novel derivatives of phenethyl-5-bromopyridylthiourea and dihydroalkoxybenzyloxopyrimidine are dual-function spermicides with potent anti-human immunodeficiency virus activity.
D'Cruz OJ; Uckun FM
Biol Reprod; 1999 Jun; 60(6):1419-28. PubMed ID: 10330101
[TBL] [Abstract][Full Text] [Related]
6. Evaluation of subchronic (13-week) and reproductive toxicity potential of intravaginal gel-microemulsion formulation of a dual-function phenyl phosphate derivative of bromo-methoxy zidovudine (compound whi-07) in B(6)C(3)F(1) mice.
D'Cruz OJ; Waurzyniak B; Yiv SH; Uckun FM
J Appl Toxicol; 2000; 20(4):319-25. PubMed ID: 10942907
[TBL] [Abstract][Full Text] [Related]
7. Thymidine kinase-independent intracellular delivery of bioactive nucleotides by aryl phosphate derivatives of bromo-methoxy zidovudine (compounds WHI-05 and WHI-07) in normal human female genital tract epithelial cells and sperm.
D'Cruz OJ; Venkatachalam TK; Uckun FM
Biol Reprod; 2001 Jan; 64(1):51-9. PubMed ID: 11133658
[TBL] [Abstract][Full Text] [Related]
8. Lack of adverse effects on fertility of female CD-1 mice exposed to repetitive intravaginal gel-microemulsion formulation of a dual-function anti-HIV agent: aryl phosphate derivative of bromo-methoxy-zidovudine (compound WHI-07).
D'Cruz OJ; Uckun FM
J Appl Toxicol; 2001; 21(4):317-22. PubMed ID: 11481666
[TBL] [Abstract][Full Text] [Related]
9. Contraceptive activity of a spermicidal aryl phosphate derivative of bromo-methoxy zidovudine (compound WHI-05) in rabbits.
D'Cruz OJ; Uckun FM
Arzneimittelforschung; 2003; 53(7):515-21. PubMed ID: 12918218
[TBL] [Abstract][Full Text] [Related]
10. Evaluation of subchronic (13 weeks) and reproductive toxicity potential of intravaginal gel-microemulsion formulation of a dual-function phenyl phosphate derivative of bromo-methoxy zidovudine (compound WHI-05) in B(6)C(3)F(1) mice.
D'Cruz OJ; Waurzyniak B; Yiv SH; Uckun FM
Contraception; 2000 Jan; 61(1):69-76. PubMed ID: 10745072
[TBL] [Abstract][Full Text] [Related]
11. Preclinical evaluation of a dual-acting microbicidal prodrug WHI-07 in combination with vanadocene dithiocarbamate in the female reproductive tract of rabbit, pig, and cat.
D'Cruz OJ; Uckun FM
Toxicol Pathol; 2007 Dec; 35(7):910-27. PubMed ID: 18098038
[TBL] [Abstract][Full Text] [Related]
12. Synthesis of dual function (5R,6R)- and (5S,6S)-5-bromo-6-methoxy-5,6-dihydro-AZT-5'-(para-bromophenyl methoxyalaninyl phosphate) as novel spermicidal and anti-HIV agents.
Jan ST; Shih MJ; Venkatachalam TK; D'Cruz OJ; Chen CL; Uckun FM
Antivir Chem Chemother; 1999 Jan; 10(1):39-46. PubMed ID: 10079878
[TBL] [Abstract][Full Text] [Related]
13. Contraceptive activity of a spermicidal aryl phosphate derivative of bromo-methoxy-zidovudine (compound WHI-07) in rabbits.
D'Cruz OJ; Uckun FM
Fertil Steril; 2003 Apr; 79(4):864-72. PubMed ID: 12749422
[TBL] [Abstract][Full Text] [Related]
14. Pre-clinical safety evaluation of novel nucleoside analogue-based dual-function microbicides (WHI-05 and WHI-07).
D'Cruz OJ; Uckun FM
J Antimicrob Chemother; 2002 Dec; 50(6):793-803. PubMed ID: 12460996
[TBL] [Abstract][Full Text] [Related]
15. Novel thiourea compounds as dual-function microbicides.
D'Cruz OJ; Venkatachalam TK; Uckun FM
Biol Reprod; 2000 Jul; 63(1):196-205. PubMed ID: 10859260
[TBL] [Abstract][Full Text] [Related]
16. Two-year toxicity and carcinogenicity studies in B(6)C(3)F(1) mice with 5-bromo-6-methoxy-5,6-dihydro-3'-azidothymidine-5'-(p-bromophenyl) methoxyalaninyl phosphate (WHI-07), a novel anti-HIV and contraceptive agent.
D'Cruz OJ; Erbeck D; Waurzyniak B; Uckun FM
Toxicology; 2002 Sep; 179(1-2):61-77. PubMed ID: 12204543
[TBL] [Abstract][Full Text] [Related]
17. Structural requirements for potent anti-human immunodeficiency virus (HIV) and sperm-immobilizing activities of cyclohexenyl thiourea and urea non-nucleoside inhibitors of HIV-1 reverse transcriptase.
D'Cruz OJ; Venkatachalam TK; Mao C; Qazi S; Uckun FM
Biol Reprod; 2002 Dec; 67(6):1959-74. PubMed ID: 12444075
[TBL] [Abstract][Full Text] [Related]
18. Developmental toxicology studies of WHI-07, a novel nucleoside analogue-based dual-function microbicide, administered intravaginally to rabbits.
D'Cruz OJ; Erbeck D; Uckun FM
Toxicol Pathol; 2003; 31(6):698-708. PubMed ID: 14585739
[TBL] [Abstract][Full Text] [Related]
19. Importance of the alanine methyl ester side chain for the biological activity profile of dual-function phenyl phosphate derivatives of bromo-methoxy-zidovudine.
Venkatachalam TK; D'Cruz OJ; Uckun FM
Antivir Chem Chemother; 2000 Jan; 11(1):31-9. PubMed ID: 10693652
[TBL] [Abstract][Full Text] [Related]
20. Short-Term (13-week) toxicity study of 5-bromo-6-methoxy-5,6-dihydro-3'-azidothymidine-5'-(p-bromophenyl) methoxyalaninyl phosphate (WHI-07), a novel anti-HIV and contraceptive agent, in B6C3F1 mice.
D'Cruz OJ; Uckun FM
Toxicol Sci; 2001 Apr; 60(2):373-8. PubMed ID: 11248150
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
