These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 10340748)

  • 1. Analysis of presenilin 1 and presenilin 2 expression and processing by newly developed monoclonal antibodies.
    Diehlmann A; Ida N; Weggen S; Grünberg J; Haass C; Masters CL; Bayer TA; Beyreuther K
    J Neurosci Res; 1999 May; 56(4):405-19. PubMed ID: 10340748
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Presenilin proteins undergo heterogeneous endoproteolysis between Thr291 and Ala299 and occur as stable N- and C-terminal fragments in normal and Alzheimer brain tissue.
    Podlisny MB; Citron M; Amarante P; Sherrington R; Xia W; Zhang J; Diehl T; Levesque G; Fraser P; Haass C; Koo EH; Seubert P; St George-Hyslop P; Teplow DB; Selkoe DJ
    Neurobiol Dis; 1997; 3(4):325-37. PubMed ID: 9173929
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Brain expression of presenilins in sporadic and early-onset, familial Alzheimer's disease.
    Mathews PM; Cataldo AM; Kao BH; Rudnicki AG; Qin X; Yang JL; Jiang Y; Picciano M; Hulette C; Lippa CF; Bird TD; Nochlin D; Walter J; Haass C; Lévesque L; Fraser PE; Andreadis A; Nixon RA
    Mol Med; 2000 Oct; 6(10):878-91. PubMed ID: 11126202
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alzheimer's disease associated presenilin-1 holoprotein and its 18-20 kDa C-terminal fragment are death substrates for proteases of the caspase family.
    Grunberg J; Walter J; Loetscher H; Deuschle U; Jacobsen H; Haass C
    Biochemistry; 1998 Feb; 37(8):2263-70. PubMed ID: 9485372
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Prominent expression of presenilin-1 in senile plaques and reactive astrocytes in Alzheimer's disease brain.
    Weggen S; Diehlmann A; Buslei R; Beyreuther K; Bayer TA
    Neuroreport; 1998 Oct; 9(14):3279-83. PubMed ID: 9831464
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Abeta42, presenilins, and Alzheimer's disease.
    Iwatsubo T
    Neurobiol Aging; 1998; 19(1 Suppl):S11-3. PubMed ID: 9562460
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of detergent-insoluble complexes containing the familial Alzheimer's disease-associated presenilins.
    Parkin ET; Hussain I; Karran EH; Turner AJ; Hooper NM
    J Neurochem; 1999 Apr; 72(4):1534-43. PubMed ID: 10098859
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Alzheimer's disease-associated presenilin 1 in neuronal cells: evidence for localization to the endoplasmic reticulum-Golgi intermediate compartment.
    Culvenor JG; Maher F; Evin G; Malchiodi-Albedi F; Cappai R; Underwood JR; Davis JB; Karran EH; Roberts GW; Beyreuther K; Masters CL
    J Neurosci Res; 1997 Sep; 49(6):719-31. PubMed ID: 9335259
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of human presenilin 1 using N-terminal specific monoclonal antibodies: Evidence that Alzheimer mutations affect proteolytic processing.
    Mercken M; Takahashi H; Honda T; Sato K; Murayama M; Nakazato Y; Noguchi K; Imahori K; Takashima A
    FEBS Lett; 1996 Jul; 389(3):297-303. PubMed ID: 8766720
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Presenilins and Alzheimer's disease: the role of A beta 42.
    Eckman CB
    J Neural Transm Suppl; 1998; 53():181-4. PubMed ID: 9700656
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
    Xia W; Zhang J; Ostaszewski BL; Kimberly WT; Seubert P; Koo EH; Shen J; Selkoe DJ
    Biochemistry; 1998 Nov; 37(47):16465-71. PubMed ID: 9843412
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [Alzheimer's disease due to presenilin mutations].
    Tabira T
    Nihon Rinsho; 2004 Jan; 62 Suppl():90-4. PubMed ID: 15011327
    [No Abstract]   [Full Text] [Related]  

  • 13. Proteolytic fragments of Alzheimer's disease-associated presenilin 1 are present in synaptic organelles and growth cone membranes of rat brain.
    Beher D; Elle C; Underwood J; Davis JB; Ward R; Karran E; Masters CL; Beyreuther K; Multhaup G
    J Neurochem; 1999 Apr; 72(4):1564-73. PubMed ID: 10098862
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of presenilin N-terminal fragments on production of amyloid beta peptide and accumulation of endogenous presenilins.
    Shirotani K; Takahashi K; Tabira T
    Neurosci Lett; 1999 Feb; 262(1):37-40. PubMed ID: 10076867
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Determination of a cleavage site of presenilin 2 protein in stably transfected SH-SY5Y human neuroblastoma cell lines.
    Shirotani K; Takahashi K; Ozawa K; Kunishita T; Tabira T
    Biochem Biophys Res Commun; 1997 Nov; 240(3):728-31. PubMed ID: 9398634
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Altered expression of apolipoprotein E, amyloid precursor protein and presenilin-1 is associated with chronic reactive gliosis in rat cortical tissue.
    Martins RN; Taddei K; Kendall C; Evin G; Bates KA; Harvey AR
    Neuroscience; 2001; 106(3):557-69. PubMed ID: 11591456
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Presenilin-1 protein expression in familial and sporadic Alzheimer's disease.
    Levey AI; Heilman CJ; Lah JJ; Nash NR; Rees HD; Wakai M; Mirra SS; Rye DB; Nochlin D; Bird TD; Mufson EJ
    Ann Neurol; 1997 Jun; 41(6):742-53. PubMed ID: 9189035
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neuronal expression and intracellular localization of presenilins in normal and Alzheimer disease brains.
    Huynh DP; Vinters HV; Ho DH; Ho VV; Pulst SM
    J Neuropathol Exp Neurol; 1997 Sep; 56(9):1009-17. PubMed ID: 9291942
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lack of specific association of presenilin 1 (PS-1) protein with plaques and tangles in Alzheimer's disease.
    Xia MQ; Berezovska O; Kim TW; Xia WM; Liao A; Tanzi RE; Selkoe D; Hyman BT
    J Neurol Sci; 1998 Jun; 158(1):15-23. PubMed ID: 9667772
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Both N-terminal and C-terminal fragments of presenilin 1 colocalize with neurofibrillary tangles in neurons and dystrophic neurites of senile plaques in Alzheimer's disease.
    Chui DH; Shirotani K; Tanahashi H; Akiyama H; Ozawa K; Kunishita T; Takahashi K; Makifuchi T; Tabira T
    J Neurosci Res; 1998 Jul; 53(1):99-106. PubMed ID: 9670996
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.