256 related articles for article (PubMed ID: 10342809)
1. Impaired beta-cell functions induced by chronic exposure of cultured human pancreatic islets to high glucose.
Marshak S; Leibowitz G; Bertuzzi F; Socci C; Kaiser N; Gross DJ; Cerasi E; Melloul D
Diabetes; 1999 Jun; 48(6):1230-6. PubMed ID: 10342809
[TBL] [Abstract][Full Text] [Related]
2. Palmitic acid increase levels of pancreatic duodenal homeobox-1 and p38/stress-activated protein kinase in islets from rats maintained on a low protein diet.
Arantes VC; Reis MA; Latorraca MQ; Ferreira F; Stoppiglia LF; Carneiro EM; Boschero AC
Br J Nutr; 2006 Dec; 96(6):1006-12. PubMed ID: 17181874
[TBL] [Abstract][Full Text] [Related]
3. Differentiation of glucose toxicity from beta cell exhaustion during the evolution of defective insulin gene expression in the pancreatic islet cell line, HIT-T15.
Moran A; Zhang HJ; Olson LK; Harmon JS; Poitout V; Robertson RP
J Clin Invest; 1997 Feb; 99(3):534-9. PubMed ID: 9022089
[TBL] [Abstract][Full Text] [Related]
4. Cytokines affect PDX-1 expression, insulin and proinsulin secretion from iNOS deficient murine islets.
Andersson AK; Börjesson A; Sandgren J; Sandler S
Mol Cell Endocrinol; 2005 Aug; 240(1-2):50-7. PubMed ID: 16023781
[TBL] [Abstract][Full Text] [Related]
5. Enhancing effects of long-term elevated glucose and palmitate on stored and secreted proinsulin-to-insulin ratios in human pancreatic islets.
Björklund A; Grill V
Diabetes; 1999 Jul; 48(7):1409-14. PubMed ID: 10389846
[TBL] [Abstract][Full Text] [Related]
6. Overexpression of repressive cAMP response element modulators in high glucose and fatty acid-treated rat islets. A common mechanism for glucose toxicity and lipotoxicity?
Zhou YP; Marlen K; Palma JF; Schweitzer A; Reilly L; Gregoire FM; Xu GG; Blume JE; Johnson JD
J Biol Chem; 2003 Dec; 278(51):51316-23. PubMed ID: 14534319
[TBL] [Abstract][Full Text] [Related]
7. Glucose-regulated proinsulin gene expression is required for adequate insulin production during chronic glucose exposure.
Leibowitz G; Uçkaya G; Oprescu AI; Cerasi E; Gross DJ; Kaiser N
Endocrinology; 2002 Sep; 143(9):3214-20. PubMed ID: 12193532
[TBL] [Abstract][Full Text] [Related]
8. Fast reversibility of glucose-induced desensitization in rat pancreatic islets. Evidence for an involvement of ionic fluxes.
Anello M; Rabuazzo AM; Degano C; Caltabiano V; Patanè G; Vigneri R; Purrello F
Diabetes; 1996 Apr; 45(4):502-6. PubMed ID: 8603773
[TBL] [Abstract][Full Text] [Related]
9. Diazoxide attenuates glucose-induced defects in first-phase insulin release and pulsatile insulin secretion in human islets.
Song SH; Rhodes CJ; Veldhuis JD; Butler PC
Endocrinology; 2003 Aug; 144(8):3399-405. PubMed ID: 12865318
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of insulin gene expression by long-term exposure of pancreatic beta cells to palmitate is dependent on the presence of a stimulatory glucose concentration.
Jacqueminet S; Briaud I; Rouault C; Reach G; Poitout V
Metabolism; 2000 Apr; 49(4):532-6. PubMed ID: 10778881
[TBL] [Abstract][Full Text] [Related]
11. Decreased expression of t-SNARE, syntaxin 1, and SNAP-25 in pancreatic beta-cells is involved in impaired insulin secretion from diabetic GK rat islets: restoration of decreased t-SNARE proteins improves impaired insulin secretion.
Nagamatsu S; Nakamichi Y; Yamamura C; Matsushima S; Watanabe T; Ozawa S; Furukawa H; Ishida H
Diabetes; 1999 Dec; 48(12):2367-73. PubMed ID: 10580425
[TBL] [Abstract][Full Text] [Related]
12. Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells.
Wang H; Iezzi M; Theander S; Antinozzi PA; Gauthier BR; Halban PA; Wollheim CB
Diabetologia; 2005 Apr; 48(4):720-31. PubMed ID: 15756539
[TBL] [Abstract][Full Text] [Related]
13. Reconstitution of glucotoxic HIT-T15 cells with somatostatin transcription factor-1 partially restores insulin promoter activity.
Harmon JS; Tanaka Y; Olson LK; Robertson RP
Diabetes; 1998 Jun; 47(6):900-4. PubMed ID: 9604866
[TBL] [Abstract][Full Text] [Related]
14. Differential expression of the insulin gene transcriptional repressor CCAAT/enhancer-binding protein beta and transactivator islet duodenum homeobox-1 in rat pancreatic beta cells during the development of diabetes mellitus.
Seufert J; Weir GC; Habener JF
J Clin Invest; 1998 Jun; 101(11):2528-39. PubMed ID: 9616224
[TBL] [Abstract][Full Text] [Related]
15. Increased susceptibility of islets from diabetes-prone Psammomys obesus to the deleterious effects of chronic glucose exposure.
Gross DJ; Leibowitz G; Cerasi E; Kaiser N
Endocrinology; 1996 Dec; 137(12):5610-5. PubMed ID: 8940391
[TBL] [Abstract][Full Text] [Related]
16. Long term exposure to fatty acids and ketones inhibits B-cell functions in human pancreatic islets of Langerhans.
Zhou YP; Grill V
J Clin Endocrinol Metab; 1995 May; 80(5):1584-90. PubMed ID: 7745004
[TBL] [Abstract][Full Text] [Related]
17. Effects of aging on insulin synthesis and secretion. Differential effects on preproinsulin messenger RNA levels, proinsulin biosynthesis, and secretion of newly made and preformed insulin in the rat.
Wang SY; Halban PA; Rowe JW
J Clin Invest; 1988 Jan; 81(1):176-84. PubMed ID: 3275693
[TBL] [Abstract][Full Text] [Related]
18. SOX6 attenuates glucose-stimulated insulin secretion by repressing PDX1 transcriptional activity and is down-regulated in hyperinsulinemic obese mice.
Iguchi H; Ikeda Y; Okamura M; Tanaka T; Urashima Y; Ohguchi H; Takayasu S; Kojima N; Iwasaki S; Ohashi R; Jiang S; Hasegawa G; Ioka RX; Magoori K; Sumi K; Maejima T; Uchida A; Naito M; Osborne TF; Yanagisawa M; Yamamoto TT; Kodama T; Sakai J
J Biol Chem; 2005 Nov; 280(45):37669-80. PubMed ID: 16148004
[TBL] [Abstract][Full Text] [Related]
19. beta-cell glucotoxicity in the Psammomys obesus model of type 2 diabetes.
Leibowitz G; Yuli M; Donath MY; Nesher R; Melloul D; Cerasi E; Gross DJ; Kaiser N
Diabetes; 2001 Feb; 50 Suppl 1():S113-7. PubMed ID: 11272167
[TBL] [Abstract][Full Text] [Related]
20. Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion.
Wang MY; Koyama K; Shimabukuro M; Mangelsdorf D; Newgard CB; Unger RH
Proc Natl Acad Sci U S A; 1998 Sep; 95(20):11921-6. PubMed ID: 9751766
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]