These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

86 related articles for article (PubMed ID: 10346938)

  • 21. Structure-activity relationship study of novel tissue transglutaminase inhibitors.
    Duval E; Case A; Stein RL; Cuny GD
    Bioorg Med Chem Lett; 2005 Apr; 15(7):1885-9. PubMed ID: 15780627
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Antitumor agents. 3. Design, synthesis, and biological evaluation of new pyridoisoquinolindione and dihydrothienoquinolindione derivatives with potent cytotoxic activity.
    Bolognese A; Correale G; Manfra M; Lavecchia A; Mazzoni O; Novellino E; La Colla P; Sanna G; Loddo R
    J Med Chem; 2004 Feb; 47(4):849-58. PubMed ID: 14761187
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Substituted thiophene-anthranilamides as potent inhibitors of human factor Xa.
    Kochanny MJ; Adler M; Ewing J; Griedel BD; Ho E; Karanjawala R; Lee W; Lentz D; Liang AM; Morrissey MM; Phillips GB; Post J; Sacchi KL; Sakata ST; Subramanyam B; Vergona R; Walters J; White KA; Whitlow M; Ye B; Zhao Z; Shaw KJ
    Bioorg Med Chem; 2007 Mar; 15(5):2127-46. PubMed ID: 17227710
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis, X-ray crystal structures, stabilities, and in vitro cytotoxic activities of new heteroarylacrylonitriles.
    Saczewski F; Reszka P; Gdaniec M; Grünert R; Bednarski PJ
    J Med Chem; 2004 Jun; 47(13):3438-49. PubMed ID: 15189040
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Design of chimeric histone deacetylase- and tyrosine kinase-inhibitors: a series of imatinib hybrides as potent inhibitors of wild-type and mutant BCR-ABL, PDGF-Rbeta, and histone deacetylases.
    Mahboobi S; Dove S; Sellmer A; Winkler M; Eichhorn E; Pongratz H; Ciossek T; Baer T; Maier T; Beckers T
    J Med Chem; 2009 Apr; 52(8):2265-79. PubMed ID: 19301902
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4-arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor.
    Romagnoli R; Baraldi PG; Carrion MD; Cara CL; Cruz-Lopez O; Salvador MK; Preti D; Tabrizi MA; Moorman AR; Vincenzi F; Borea PA; Varani K
    J Med Chem; 2012 Sep; 55(17):7719-35. PubMed ID: 22889387
    [TBL] [Abstract][Full Text] [Related]  

  • 27. 2-Aminothiophene-3-carboxylates and carboxamides as adenosine A1 receptor allosteric enhancers.
    Nikolakopoulos G; Figler H; Linden J; Scammells PJ
    Bioorg Med Chem; 2006 Apr; 14(7):2358-65. PubMed ID: 16314104
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Benzothiophene inhibitors of MK2. Part 1: structure-activity relationships, assessments of selectivity and cellular potency.
    Anderson DR; Meyers MJ; Kurumbail RG; Caspers N; Poda GI; Long SA; Pierce BS; Mahoney MW; Mourey RJ
    Bioorg Med Chem Lett; 2009 Aug; 19(16):4878-81. PubMed ID: 19616945
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Studies of the metabolic stability in cells of 5-(trifluoroacetyl)thiophene-2-carboxamides and identification of more stable class II histone deacetylase (HDAC) inhibitors.
    Scarpelli R; Di Marco A; Ferrigno F; Laufer R; Marcucci I; Muraglia E; Ontoria JM; Rowley M; Serafini S; Steinkühler C; Jones P
    Bioorg Med Chem Lett; 2008 Dec; 18(23):6078-82. PubMed ID: 18952417
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Structure-activity relationship of 6-methylidene penems bearing 6,5 bicyclic heterocycles as broad-spectrum beta-lactamase inhibitors: evidence for 1,4-thiazepine intermediates with C7 R stereochemistry by computational methods.
    Venkatesan AM; Agarwal A; Abe T; Ushirogochi H; Yamamura I; Ado M; Tsuyoshi T; Dos Santos O; Gu Y; Sum FW; Li Z; Francisco G; Lin YI; Petersen PJ; Yang Y; Kumagai T; Weiss WJ; Shlaes DM; Knox JR; Mansour TS
    J Med Chem; 2006 Jul; 49(15):4623-37. PubMed ID: 16854068
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Discovery of 2-pyrimidyl-5-amidothiophenes as potent inhibitors for AKT: synthesis and SAR studies.
    Lin X; Murray JM; Rico AC; Wang MX; Chu DT; Zhou Y; Del Rosario M; Kaufman S; Ma S; Fang E; Crawford K; Jefferson AB
    Bioorg Med Chem Lett; 2006 Aug; 16(16):4163-8. PubMed ID: 16765046
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Design, syntheses, biological evaluation, and docking studies of 2-substituted 5-methylsulfonyl-1-phenyl-1H-indoles: potent and selective in vitro cyclooxygenase-2 inhibitors.
    Cruz-López O; Díaz-Mochón JJ; Campos JM; Entrena A; Núñez MT; Labeaga L; Orjales A; Gallo MA; Espinosa A
    ChemMedChem; 2007 Jan; 2(1):88-100. PubMed ID: 17131462
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Synthesis and Molecular Docking of New Thiophene Derivatives as Lactate Dehydrogenase-A Inhibitors.
    Amr AEE; El-Shehry MF; Ibrahim AA; Hosni HM; Al-Omar MA; Ghabbour HA
    Mini Rev Med Chem; 2019; 19(10):833-841. PubMed ID: 30760188
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N-(substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor.
    Romagnoli R; Baraldi PG; Carrion MD; Cara CL; Cruz-Lopez O; Iaconinoto MA; Preti D; Shryock JC; Moorman AR; Vincenzi F; Varani K; Andrea Borea P
    J Med Chem; 2008 Sep; 51(18):5875-9. PubMed ID: 18729349
    [TBL] [Abstract][Full Text] [Related]  

  • 35. 2-Amino-3-benzoylthiophene allosteric enhancers of A1 adenosine agonist binding: new 3, 4-, and 5-modifications.
    Lütjens H; Zickgraf A; Figler H; Linden J; Olsson RA; Scammells PJ
    J Med Chem; 2003 May; 46(10):1870-7. PubMed ID: 12723950
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Synthesis of 2-amino-3-heteroaroylthiophenes and evaluation of their activity as potential allosteric enhancers at the human A1 receptor.
    Baraldi PG; Pavani MG; Shryock JC; Moorman AR; Iannotta V; Borea PA; Romagnoli R
    Eur J Med Chem; 2004 Oct; 39(10):855-65. PubMed ID: 15464619
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Syntheses of tetrahydrothiophenes and tetrahydrofurans and studies of their derivatives as melanocortin-4 receptor ligands.
    Tran JA; Chen CW; Tucci FC; Jiang W; Fleck BA; Chen C
    Bioorg Med Chem Lett; 2008 Feb; 18(3):1124-30. PubMed ID: 18082401
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Design, synthesis, and structure-activity relationships of thieno[2,3-b]pyridin-4-one derivatives as a novel class of potent, orally active, non-peptide luteinizing hormone-releasing hormone receptor antagonists.
    Imada T; Cho N; Imaeda T; Hayase Y; Sasaki S; Kasai S; Harada M; Matsumoto H; Endo S; Suzuki N; Furuya S
    J Med Chem; 2006 Jun; 49(13):3809-25. PubMed ID: 16789738
    [TBL] [Abstract][Full Text] [Related]  

  • 39. N-(thiazol-2-yl)-2-thiophene carboxamide derivatives as Abl inhibitors identified by a pharmacophore-based database screening of commercially available compounds.
    Manetti F; Falchi F; Crespan E; Schenone S; Maga G; Botta M
    Bioorg Med Chem Lett; 2008 Aug; 18(15):4328-31. PubMed ID: 18621522
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The crystal structures of human alpha-thrombin complexed with active site-directed diamino benzo[b]thiophene derivatives: a binding mode for a structurally novel class of inhibitors.
    Chirgadze NY; Sall DJ; Briggs SL; Clawson DK; Zhang M; Smith GF; Schevitz RW
    Protein Sci; 2000 Jan; 9(1):29-36. PubMed ID: 10739244
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.