120 related articles for article (PubMed ID: 10350482)
21. Transmembrane segment 1 of human P-glycoprotein contributes to the drug-binding pocket.
Loo TW; Bartlett MC; Clarke DM
Biochem J; 2006 Jun; 396(3):537-45. PubMed ID: 16492138
[TBL] [Abstract][Full Text] [Related]
22. Transmembrane domain (TM) 9 represents a novel site in P-glycoprotein that affects drug resistance and cooperates with TM6 to mediate [125I]iodoarylazidoprazosin labeling.
Song J; Melera PW
Mol Pharmacol; 2001 Aug; 60(2):254-61. PubMed ID: 11455011
[TBL] [Abstract][Full Text] [Related]
23. Stimulation of P-glycoprotein ATPase by analogues of tetramethylrosamine: coupling of drug binding at the "R" site to the ATP hydrolysis transition state.
Tombline G; Donnelly DJ; Holt JJ; You Y; Ye M; Gannon MK; Nygren CL; Detty MR
Biochemistry; 2006 Jul; 45(26):8034-47. PubMed ID: 16800628
[TBL] [Abstract][Full Text] [Related]
24. Schisandrol A from Schisandra chinensis reverses P-glycoprotein-mediated multidrug resistance by affecting Pgp-substrate complexes.
Fong WF; Wan CK; Zhu GY; Chattopadhyay A; Dey S; Zhao Z; Shen XL
Planta Med; 2007 Mar; 73(3):212-20. PubMed ID: 17318783
[TBL] [Abstract][Full Text] [Related]
25. The drug-binding pocket of the human multidrug resistance P-glycoprotein is accessible to the aqueous medium.
Loo TW; Bartlett MC; Clarke DM
Biochemistry; 2004 Sep; 43(38):12081-9. PubMed ID: 15379547
[TBL] [Abstract][Full Text] [Related]
26. A functional role of intracellular loops of human multidrug resistance protein 1.
Ren XQ; Furukawa T; Yamamoto M; Aoki S; Kobayashi M; Nakagawa M; Akiyama S
J Biochem; 2006 Sep; 140(3):313-8. PubMed ID: 16861249
[TBL] [Abstract][Full Text] [Related]
27. (+/-)-3'-O, 4'-O-dicynnamoyl-cis-khellactone, a derivative of (+/-)-praeruptorin A, reverses P-glycoprotein mediated multidrug resistance in cancer cells.
Shen X; Chen G; Zhu G; Fong WF
Bioorg Med Chem; 2006 Nov; 14(21):7138-45. PubMed ID: 16875827
[TBL] [Abstract][Full Text] [Related]
28. Cysteine residues are involved in structure and function of melanocortin 1 receptor: Substitution of a cysteine residue in transmembrane segment two converts an agonist to antagonist.
Frändberg PA; Doufexis M; Kapas S; Chhajlani V
Biochem Biophys Res Commun; 2001 Mar; 281(4):851-7. PubMed ID: 11237737
[TBL] [Abstract][Full Text] [Related]
29. Interaction of the P-glycoprotein multidrug efflux pump with cholesterol: effects on ATPase activity, drug binding and transport.
Eckford PD; Sharom FJ
Biochemistry; 2008 Dec; 47(51):13686-98. PubMed ID: 19049391
[TBL] [Abstract][Full Text] [Related]
30. Inhibition of P-glycoprotein (ABCB1)- and multidrug resistance-associated protein 1 (ABCC1)-mediated transport by the orally administered inhibitor, CBT-1((R)).
Robey RW; Shukla S; Finley EM; Oldham RK; Barnett D; Ambudkar SV; Fojo T; Bates SE
Biochem Pharmacol; 2008 Mar; 75(6):1302-12. PubMed ID: 18234154
[TBL] [Abstract][Full Text] [Related]
31. Probing the salmeterol binding site on the beta 2-adrenergic receptor using a novel photoaffinity ligand, [(125)I]iodoazidosalmeterol.
Rong Y; Arbabian M; Thiriot DS; Seibold A; Clark RB; Ruoho AE
Biochemistry; 1999 Aug; 38(35):11278-86. PubMed ID: 10471277
[TBL] [Abstract][Full Text] [Related]
32. Catalytic mechanism of P-glycoprotein.
Senior AE
Acta Physiol Scand Suppl; 1998 Aug; 643():213-8. PubMed ID: 9789563
[TBL] [Abstract][Full Text] [Related]
33. Conferone from Ferula schtschurowskiana enhances vinblastine cytotoxicity in MDCK-MDR1 cells by competitively inhibiting P-glycoprotein transport.
Barthomeuf C; Demeule M; Grassi J; Saidkhodjaev A; Beliveau R
Planta Med; 2006 Jun; 72(7):634-9. PubMed ID: 16739070
[TBL] [Abstract][Full Text] [Related]
34. Functional characterization of a glycine 185-to-valine substitution in human P-glycoprotein by using a vaccinia-based transient expression system.
Ramachandra M; Ambudkar SV; Gottesman MM; Pastan I; Hrycyna CA
Mol Biol Cell; 1996 Oct; 7(10):1485-98. PubMed ID: 8898356
[TBL] [Abstract][Full Text] [Related]
35. The molecular basis of the action of disulfiram as a modulator of the multidrug resistance-linked ATP binding cassette transporters MDR1 (ABCB1) and MRP1 (ABCC1).
Sauna ZE; Peng XH; Nandigama K; Tekle S; Ambudkar SV
Mol Pharmacol; 2004 Mar; 65(3):675-84. PubMed ID: 14978246
[TBL] [Abstract][Full Text] [Related]
36. Biochemical mechanism of modulation of human P-glycoprotein (ABCB1) by curcumin I, II, and III purified from Turmeric powder.
Chearwae W; Anuchapreeda S; Nandigama K; Ambudkar SV; Limtrakul P
Biochem Pharmacol; 2004 Nov; 68(10):2043-52. PubMed ID: 15476675
[TBL] [Abstract][Full Text] [Related]
37. Evidence for a requirement for ATP hydrolysis at two distinct steps during a single turnover of the catalytic cycle of human P-glycoprotein.
Sauna ZE; Ambudkar SV
Proc Natl Acad Sci U S A; 2000 Mar; 97(6):2515-20. PubMed ID: 10716986
[TBL] [Abstract][Full Text] [Related]
38. N-(p-azido-3-[125I]iodophenethyl)spiperone binds to specific regions of P-glycoprotein and another multidrug binding protein, spiperophilin, in human neuroblastoma cells.
Safa AR; Agresti M; Bryk D; Tamai I
Biochemistry; 1994 Jan; 33(1):256-65. PubMed ID: 7904476
[TBL] [Abstract][Full Text] [Related]
39. Functional analysis of P-glycoprotein mutants identifies predicted transmembrane domain 11 as a putative drug binding site.
Kajiji S; Talbot F; Grizzuti K; Van Dyke-Phillips V; Agresti M; Safa AR; Gros P
Biochemistry; 1993 Apr; 32(16):4185-94. PubMed ID: 7682843
[TBL] [Abstract][Full Text] [Related]
40. Loss of cyclosporin and azidopine binding are associated with altered ATPase activity by a mutant P-glycoprotein with deleted phe(335).
Chen KG; Lacayo NJ; Durán GE; Cohen D; Sikic BI
Mol Pharmacol; 2000 Apr; 57(4):769-77. PubMed ID: 10727524
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
