These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

274 related articles for article (PubMed ID: 10383380)

  • 1. Mutagenesis identifies new signals for beta-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Abeta42.
    Perez RG; Soriano S; Hayes JD; Ostaszewski B; Xia W; Selkoe DJ; Chen X; Stokin GB; Koo EH
    J Biol Chem; 1999 Jul; 274(27):18851-6. PubMed ID: 10383380
    [TBL] [Abstract][Full Text] [Related]  

  • 2. X11alpha modulates secretory and endocytic trafficking and metabolism of amyloid precursor protein: mutational analysis of the YENPTY sequence.
    King GD; Perez RG; Steinhilb ML; Gaut JR; Turner RS
    Neuroscience; 2003; 120(1):143-54. PubMed ID: 12849748
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amyloid beta 42 peptide (Abeta42)-lowering compounds directly bind to Abeta and interfere with amyloid precursor protein (APP) transmembrane dimerization.
    Richter L; Munter LM; Ness J; Hildebrand PW; Dasari M; Unterreitmeier S; Bulic B; Beyermann M; Gust R; Reif B; Weggen S; Langosch D; Multhaup G
    Proc Natl Acad Sci U S A; 2010 Aug; 107(33):14597-602. PubMed ID: 20679249
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ELISA analysis of beta-secretase cleavage of the Swedish amyloid precursor protein in the secretory and endocytic pathways.
    Steinhilb ML; Turner RS; Gaut JR
    J Neurochem; 2002 Mar; 80(6):1019-28. PubMed ID: 11953452
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rapid endocytosis of the low density lipoprotein receptor-related protein modulates cell surface distribution and processing of the beta-amyloid precursor protein.
    Cam JA; Zerbinatti CV; Li Y; Bu G
    J Biol Chem; 2005 Apr; 280(15):15464-70. PubMed ID: 15705569
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sequences from the low density lipoprotein receptor-related protein (LRP) cytoplasmic domain enhance amyloid beta protein production via the beta-secretase pathway without altering amyloid precursor protein/LRP nuclear signaling.
    Yoon IS; Pietrzik CU; Kang DE; Koo EH
    J Biol Chem; 2005 May; 280(20):20140-7. PubMed ID: 15772078
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The endocytotic pathway is required for increased A beta 42 secretion during apoptosis.
    Sodhi CP; Rampalli S; Perez RG; Koo EH; Quinn B; Gottardi-Littell NR
    Brain Res Mol Brain Res; 2004 Sep; 128(2):201-11. PubMed ID: 15363895
    [TBL] [Abstract][Full Text] [Related]  

  • 8. alpha-secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Abeta generation.
    Jäger S; Leuchtenberger S; Martin A; Czirr E; Wesselowski J; Dieckmann M; Waldron E; Korth C; Koo EH; Heneka M; Weggen S; Pietrzik CU
    J Neurochem; 2009 Dec; 111(6):1369-82. PubMed ID: 19804379
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
    Xia W; Zhang J; Ostaszewski BL; Kimberly WT; Seubert P; Koo EH; Shen J; Selkoe DJ
    Biochemistry; 1998 Nov; 37(47):16465-71. PubMed ID: 9843412
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Abeta42-lowering nonsteroidal anti-inflammatory drugs preserve intramembrane cleavage of the amyloid precursor protein (APP) and ErbB-4 receptor and signaling through the APP intracellular domain.
    Weggen S; Eriksen JL; Sagi SA; Pietrzik CU; Golde TE; Koo EH
    J Biol Chem; 2003 Aug; 278(33):30748-54. PubMed ID: 12777371
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Physiological mouse brain Abeta levels are not related to the phosphorylation state of threonine-668 of Alzheimer's APP.
    Sano Y; Nakaya T; Pedrini S; Takeda S; Iijima-Ando K; Iijima K; Mathews PM; Itohara S; Gandy S; Suzuki T
    PLoS One; 2006 Dec; 1(1):e51. PubMed ID: 17183681
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Increased generation of alternatively cleaved beta-amyloid peptides in cells expressing mutants of the amyloid precursor protein defective in endocytosis.
    Cescato R; Dumermuth E; Spiess M; Paganetti PA
    J Neurochem; 2000 Mar; 74(3):1131-9. PubMed ID: 10693945
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synaptotagmins interact with APP and promote Aβ generation.
    Gautam V; D'Avanzo C; Berezovska O; Tanzi RE; Kovacs DM
    Mol Neurodegener; 2015 Jul; 10():31. PubMed ID: 26202512
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of sorting signals in the beta-amyloid precursor protein cytoplasmic domain.
    Lai A; Sisodia SS; Trowbridge IS
    J Biol Chem; 1995 Feb; 270(8):3565-73. PubMed ID: 7876092
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The A673T mutation in the amyloid precursor protein reduces the production of β-amyloid protein from its β-carboxyl terminal fragment in cells.
    Kokawa A; Ishihara S; Fujiwara H; Nobuhara M; Iwata M; Ihara Y; Funamoto S
    Acta Neuropathol Commun; 2015 Nov; 3():66. PubMed ID: 26531305
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential effects of the swedish mutant amyloid precursor protein on beta-amyloid accumulation and secretion in neurons and nonneuronal cells.
    Forman MS; Cook DG; Leight S; Doms RW; Lee VM
    J Biol Chem; 1997 Dec; 272(51):32247-53. PubMed ID: 9405428
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence.
    Kimura A; Hata S; Suzuki T
    J Biol Chem; 2016 Nov; 291(46):24041-24053. PubMed ID: 27687728
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tyr687 dependent APP endocytosis and Abeta production.
    Rebelo S; Vieira SI; Esselmann H; Wiltfang J; da Cruz e Silva EF; da Cruz e Silva OA
    J Mol Neurosci; 2007; 32(1):1-8. PubMed ID: 17873282
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Axonal amyloid precursor protein and its fragments undergo somatodendritic endocytosis and processing.
    Niederst ED; Reyna SM; Goldstein LS
    Mol Biol Cell; 2015 Jan; 26(2):205-17. PubMed ID: 25392299
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Amyloid precursor-like protein 1 influences endocytosis and proteolytic processing of the amyloid precursor protein.
    Neumann S; Schöbel S; Jäger S; Trautwein A; Haass C; Pietrzik CU; Lichtenthaler SF
    J Biol Chem; 2006 Mar; 281(11):7583-94. PubMed ID: 16344553
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.