These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 10387042)

  • 1. Mechanistic insights into the inhibition of serine proteases by monocyclic lactams.
    Wilmouth RC; Kassamally S; Westwood NJ; Sheppard RJ; Claridge TD; Aplin RT; Wright PA; Pritchard GJ; Schofield CJ
    Biochemistry; 1999 Jun; 38(25):7989-98. PubMed ID: 10387042
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex.
    Wilmouth RC; Westwood NJ; Anderson K; Brownlee W; Claridge TD; Clifton IJ; Pritchard GJ; Aplin RT; Schofield CJ
    Biochemistry; 1998 Dec; 37(50):17506-13. PubMed ID: 9860865
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 'pH-jump' crystallographic analyses of gamma-lactam-porcine pancreatic elastase complexes.
    Wright PA; Wilmouth RC; Clifton IJ; Schofield CJ
    Biochem J; 2000 Oct; 351 Pt 2(Pt 2):335-40. PubMed ID: 11023818
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structure of an elastase-specific inhibitor elafin complexed with porcine pancreatic elastase determined at 1.9 A resolution.
    Tsunemi M; Matsuura Y; Sakakibara S; Katsube Y
    Biochemistry; 1996 Sep; 35(36):11570-6. PubMed ID: 8794736
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystallographic study of a beta-lactam inhibitor complex with elastase at 1.84 A resolution.
    Navia MA; Springer JP; Lin TY; Williams HR; Firestone RA; Pisano JM; Doherty JB; Finke PE; Hoogsteen K
    Nature; 1987 May 7-13; 327(6117):79-82. PubMed ID: 3646481
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel natural product 5,5-trans-lactone inhibitors of human alpha-thrombin: mechanism of action and structural studies.
    Weir MP; Bethell SS; Cleasby A; Campbell CJ; Dennis RJ; Dix CJ; Finch H; Jhoti H; Mooney CJ; Patel S; Tang CM; Ward M; Wonacott AJ; Wharton CW
    Biochemistry; 1998 May; 37(19):6645-57. PubMed ID: 9578548
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure of porcine pancreatic elastase complexed with FR901277, a novel macrocyclic inhibitor of elastases, at 1.6 A resolution.
    Nakanishi I; Kinoshita T; Sato A; Tada T
    Biopolymers; 2000 Apr; 53(5):434-45. PubMed ID: 10738204
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Toward better antibiotics: crystallographic studies of a novel class of DD-peptidase/beta-lactamase inhibitors.
    Silvaggi NR; Kaur K; Adediran SA; Pratt RF; Kelly JA
    Biochemistry; 2004 Jun; 43(22):7046-53. PubMed ID: 15170342
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structure of a bacterial signal peptidase in complex with a beta-lactam inhibitor.
    Paetzel M; Dalbey RE; Strynadka NC
    Nature; 1998 Nov; 396(6707):186-90. PubMed ID: 9823901
    [TBL] [Abstract][Full Text] [Related]  

  • 10. beta-Lactam derivatives as enzyme inhibitors: N-substituted derivatives of (S)-4-oxoazetidine-2-carboxylate as inhibitors of elastase and papain.
    Achilles K; Schneider M; Schirmeister T; Otto HH
    Pharmazie; 2000 Nov; 55(11):798-802. PubMed ID: 11125993
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel mechanism of inhibition of elastase by beta-lactams is defined by two inhibitor crystal complexes.
    Taylor P; Anderson V; Dowden J; Flitsch SL; Turner NJ; Loughran K; Walkinshaw MD
    J Biol Chem; 1999 Aug; 274(35):24901-5. PubMed ID: 10455164
    [TBL] [Abstract][Full Text] [Related]  

  • 12. beta-Lactam derivatives as enzyme inhibitors: derivatives of (E)-2-[(RS)-1-(4-methoxyphenyl)-2-oxo-4-phenylazetidin-3-ylidene]propionic acid.
    Venz C; Otto HH
    Pharmazie; 2001 Sep; 56(9):686-90. PubMed ID: 11593986
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nature of the inactivation of elastase by N-peptidyl-O-aroyl hydroxylamine as a function of pH.
    Ding X; Rasmussen BF; Demuth HU; Ringe D; Steinmetz AC
    Biochemistry; 1995 Jun; 34(23):7749-56. PubMed ID: 7779821
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Multipolar interactions in the D pocket of thrombin: large differences between tricyclic imide and lactam inhibitors.
    Schweizer E; Hoffmann-Röder A; Olsen JA; Seiler P; Obst-Sander U; Wagner B; Kansy M; Banner DW; Diederich F
    Org Biomol Chem; 2006 Jun; 4(12):2364-75. PubMed ID: 16763681
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Azetidine-2,4-diones (4-oxo-beta-lactams) as scaffolds for designing elastase inhibitors.
    Mulchande J; Guedes RC; Tsang WY; Page MI; Moreira R; Iley J
    J Med Chem; 2008 Mar; 51(6):1783-90. PubMed ID: 18290604
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural and functional study of an Anemonia elastase inhibitor, a "nonclassical" Kazal-type inhibitor from Anemonia sulcata.
    Hemmi H; Kumazaki T; Yoshizawa-Kumagaye K; Nishiuchi Y; Yoshida T; Ohkubo T; Kobayashi Y
    Biochemistry; 2005 Jul; 44(28):9626-36. PubMed ID: 16008348
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of class A and class C beta-lactamases by penems: crystallographic structures of a novel 1,4-thiazepine intermediate.
    Nukaga M; Abe T; Venkatesan AM; Mansour TS; Bonomo RA; Knox JR
    Biochemistry; 2003 Nov; 42(45):13152-9. PubMed ID: 14609325
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanism of inhibition of human leucocyte elastase by beta-lactams. 2. Stability, reactivation kinetics, and products of beta-lactam-derived E-I complexes.
    Green BG; Chabin R; Mills S; Underwood DJ; Shah SK; Kuo D; Gale P; Maycock AL; Liesch J; Burgey CS
    Biochemistry; 1995 Nov; 34(44):14331-43. PubMed ID: 7578037
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site.
    Katz BA; Elrod K; Luong C; Rice MJ; Mackman RL; Sprengeler PA; Spencer J; Hataye J; Janc J; Link J; Litvak J; Rai R; Rice K; Sideris S; Verner E; Young W
    J Mol Biol; 2001 Apr; 307(5):1451-86. PubMed ID: 11292354
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanistic insights into the inhibition of prostate specific antigen by beta-lactam class compounds.
    Singh P; Williams SA; Shah MH; Lectka T; Pritchard GJ; Isaacs JT; Denmeade SR
    Proteins; 2008 Mar; 70(4):1416-28. PubMed ID: 17894328
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.