BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

661 related articles for article (PubMed ID: 10395485)

  • 1. Antitumor agents. 194. Synthesis and biological evaluations of 4-beta-mono-, -di-, and -trisubstituted aniline-4'-O-demethyl-podophyllotoxin and related compounds with improved pharmacological profiles.
    Zhu XK; Guan J; Tachibana Y; Bastow KF; Cho SJ; Cheng HH; Cheng YC; Gurwith M; Lee KH
    J Med Chem; 1999 Jul; 42(13):2441-6. PubMed ID: 10395485
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological activity of sulfonamide derivatives of epipodophyllotoxin.
    Guianvarc'h D; Duca M; Boukarim C; Kraus-Berthier L; Léonce S; Pierré A; Pfeiffer B; Renard P; Arimondo PB; Monneret C; Dauzonne D
    J Med Chem; 2004 Apr; 47(9):2365-74. PubMed ID: 15084135
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Antitumor agents. 234. Design, synthesis, and biological evaluation of novel 4beta-[(4' '-benzamido)-amino]-4'-o-demethyl-epipodophyllotoxin derivatives.
    Xiao Z; Bastow KF; Vance JR; Sidwell RS; Wang HK; Chen MS; Shi Q; Lee KH
    J Med Chem; 2004 Oct; 47(21):5140-8. PubMed ID: 15456257
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel carbamate derivatives of 4-beta-amino-4'-O-demethyl-4-desoxypodophyllotoxin as inhibitors of topoisomerase II: synthesis and biological evaluation.
    Duca M; Arimondo PB; Léonce S; Pierré A; Pfeiffer B; Monneret C; Dauzonne D
    Org Biomol Chem; 2005 Mar; 3(6):1074-80. PubMed ID: 15750651
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antitumor activity of a novel podophyllotoxin derivative (TOP-53) against lung cancer and lung metastatic cancer.
    Utsugi T; Shibata J; Sugimoto Y; Aoyagi K; Wierzba K; Kobunai T; Terada T; Oh-hara T; Tsuruo T; Yamada Y
    Cancer Res; 1996 Jun; 56(12):2809-14. PubMed ID: 8665518
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antitumor agents. 164. Podophenazine, 2'',3''-dichloropodophenazine, benzopodophenazine, and their 4 beta-p-nitroaniline derivatives as novel DNA topoisomerase II inhibitors.
    Cho SJ; Kashiwada Y; Bastow KF; Cheng YC; Lee KH
    J Med Chem; 1996 Mar; 39(7):1396-402. PubMed ID: 8691469
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-activity relationships for substituted bis(acridine-4-carboxamides): a new class of anticancer agents.
    Gamage SA; Spicer JA; Atwell GJ; Finlay GJ; Baguley BC; Denny WA
    J Med Chem; 1999 Jul; 42(13):2383-93. PubMed ID: 10395479
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antitumor agents. Part 235: Novel 4'-ester etoposide analogues as potent DNA topoisomerase II inhibitors with improved therapeutic potential.
    Xiao Z; Vance JR; Bastow KF; Brossi A; Wang HK; Lee KH
    Bioorg Med Chem; 2004 Jun; 12(12):3363-9. PubMed ID: 15158805
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and biological study of a new series of 4'-demethylepipodophyllotoxin derivatives.
    Duca M; Guianvarc'h D; Meresse P; Bertounesque E; Dauzonne D; Kraus-Berthier L; Thirot S; Léonce S; Pierré A; Pfeiffer B; Renard P; Arimondo PB; Monneret C
    J Med Chem; 2005 Jan; 48(2):593-603. PubMed ID: 15658872
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Antitumor agents. Part 227: Studies on novel 4'-O-demethyl-epipodophyllotoxins as antitumor agents targeting topoisomerase II.
    Xiao Z; Bastow KF; Vance JR; Lee KH
    Bioorg Med Chem; 2004 Jun; 12(12):3339-44. PubMed ID: 15158802
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Antitumor agents. Part 230: C4'-esters of GL-331 as cytotoxic agents and DNA topoisomerase II inhibitors.
    Han S; Xiao Z; Bastow KF; Lee KH
    Bioorg Med Chem Lett; 2004 Jun; 14(11):2979-82. PubMed ID: 15125972
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and antitumor activity of novel benzimidazole-5-carboxylic acid derivatives and their transition metal complexes as topoisomerease II inhibitors.
    Galal SA; Hegab KH; Hashem AM; Youssef NS
    Eur J Med Chem; 2010 Dec; 45(12):5685-91. PubMed ID: 20884089
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and biological evaluation of new 4β-anilino-4'-O-demethyl-4-desoxypodophyllotoxin derivatives as potential antitumor agents.
    Wang L; Yang F; Yang X; Guan X; Hu C; Liu T; He Q; Yang B; Hu Y
    Eur J Med Chem; 2011 Jan; 46(1):285-96. PubMed ID: 21145139
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of new 4beta-anilino- and 4beta-imido-substituted podophyllotoxin congeners.
    Kamal A; Gayatri NL; Reddy DR; Mohan Reddy PS; Arifuddin M; Dastidar SG; Kondapi AK; Rajkumar M
    Bioorg Med Chem; 2005 Nov; 13(22):6218-25. PubMed ID: 16061385
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, and biological testing of 4beta-[(4-substituted)-1,2,3-triazol-1-yl]podophyllotoxin analogues as antitumor agents.
    Reddy PB; Paul DV; Agrawal SK; Saxena AK; Kumar HM; Qazi GN
    Arch Pharm (Weinheim); 2008 Feb; 341(2):126-31. PubMed ID: 18214838
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel 4 beta-anilino-podophyllotoxin derivatives: design synthesis and biological evaluation as potent DNA-topoisomerase II poisons and anti-MDR agents.
    Hu C; Xu D; Du W; Qian S; Wang L; Lou J; He Q; Yang B; Hu Y
    Mol Biosyst; 2010 Feb; 6(2):410-20. PubMed ID: 20094661
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and antitumor activity of new glycosides of epipodophyllotoxin, analogues of etoposide, and NK 611.
    Daley L; Guminski Y; Demerseman P; Kruczynski A; Etiévant C; Imbert T; Hill BT; Monneret C
    J Med Chem; 1998 Nov; 41(23):4475-85. PubMed ID: 9804687
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and antitumor activity of 4-aminomethylthioxanthenone and 5-aminomethylbenzothiopyranoindazole derivatives.
    Perni RB; Wentland MP; Huang JI; Powles RG; Aldous S; Klingbeil KM; Peverly AD; Robinson RG; Corbett TH; Jones JL; Mattes KC; Rake JB; Coughlin SA
    J Med Chem; 1998 Sep; 41(19):3645-54. PubMed ID: 9733489
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Potent antitumor 9-anilinoacridines bearing an alkylating N-mustard residue on the anilino ring: synthesis and biological activity.
    Bacherikov VA; Chou TC; Dong HJ; Zhang X; Chen CH; Lin YW; Tsai TJ; Lee RZ; Liu LF; Su TL
    Bioorg Med Chem; 2005 Jun; 13(12):3993-4006. PubMed ID: 15911312
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and antitumor evaluation of 2,5-disubstituted-indazolo[4, 3-gh]isoquinolin-6(2H)-ones (9-aza-anthrapyrazoles).
    Krapcho AP; Menta E; Oliva A; Di Domenico R; Fiocchi L; Maresch ME; Gallagher CE; Hacker MP; Beggiolin G; Giuliani FC; Pezzoni G; Spinelli S
    J Med Chem; 1998 Dec; 41(27):5429-44. PubMed ID: 9876113
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 34.