133 related articles for article (PubMed ID: 10395488)
1. Subtype-selective N-methyl-D-aspartate receptor antagonists: synthesis and biological evaluation of 1-(arylalkynyl)-4-benzylpiperidines.
Wright JL; Gregory TF; Bigge CF; Boxer PA; Serpa K; Meltzer LT; Wise LD; Cai SX; Hawkinson JE; Konkoy CS; Whittemore ER; Woodward RM; Zhou ZL
J Med Chem; 1999 Jul; 42(13):2469-77. PubMed ID: 10395488
[TBL] [Abstract][Full Text] [Related]
2. Subtype-selective N-methyl-D-aspartate receptor antagonists: synthesis and biological evaluation of 1-(heteroarylalkynyl)-4-benzylpiperidines.
Wright JL; Gregory TF; Kesten SR; Boxer PA; Serpa KA; Meltzer LT; Wise LD; Espitia SA; Konkoy CS; Whittemore ER; Woodward RM
J Med Chem; 2000 Sep; 43(18):3408-19. PubMed ID: 10978188
[TBL] [Abstract][Full Text] [Related]
3. Synthesis of N-substituted 4-(4-hydroxyphenyl)piperidines, 4-(4-hydroxybenzyl)piperidines, and (+/-)-3-(4-hydroxyphenyl)pyrrolidines: selective antagonists at the 1A/2B NMDA receptor subtype.
Guzikowski AP; Tamiz AP; Acosta-Burruel M; Hong-Bae S; Cai SX; Hawkinson JE; Keana JF; Kesten SR; Shipp CT; Tran M; Whittemore ER; Woodward RM; Wright JL; Zhou ZL
J Med Chem; 2000 Mar; 43(5):984-94. PubMed ID: 10715162
[TBL] [Abstract][Full Text] [Related]
4. Structure-activity relationships for a series of bis(phenylalkyl)amines: potent subtype-selective inhibitors of N-methyl-D-aspartate receptors.
Tamiz AP; Whittemore ER; Zhou ZL; Huang JC; Drewe JA; Chen JC; Cai SX; Weber E; Woodward RM; Keana JF
J Med Chem; 1998 Aug; 41(18):3499-506. PubMed ID: 9719603
[TBL] [Abstract][Full Text] [Related]
5. Differing effects of N-methyl-D-aspartate receptor subtype selective antagonists on dyskinesias in levodopa-treated 1-methyl-4-phenyl-tetrahydropyridine monkeys.
Blanchet PJ; Konitsiotis S; Whittemore ER; Zhou ZL; Woodward RM; Chase TN
J Pharmacol Exp Ther; 1999 Sep; 290(3):1034-40. PubMed ID: 10454475
[TBL] [Abstract][Full Text] [Related]
6. Structure-activity relationship of N-(phenylalkyl)cinnamides as novel NR2B subtype-selective NMDA receptor antagonists.
Tamiz AP; Cai SX; Zhou ZL; Yuen PW; Schelkun RM; Whittemore ER; Weber E; Woodward RM; Keana JF
J Med Chem; 1999 Aug; 42(17):3412-20. PubMed ID: 10464027
[TBL] [Abstract][Full Text] [Related]
7. 4-Hydroxy-1-[2-(4-hydroxyphenoxy)ethyl]-4-(4-methylbenzyl)piperidine: a novel, potent, and selective NR1/2B NMDA receptor antagonist.
Zhou ZL; Cai SX; Whittemore ER; Konkoy CS; Espitia SA; Tran M; Rock DM; Coughenour LL; Hawkinson JE; Boxer PA; Bigge CF; Wise LD; Weber E; Woodward RM; Keana JF
J Med Chem; 1999 Jul; 42(15):2993-3000. PubMed ID: 10425109
[TBL] [Abstract][Full Text] [Related]
8. Antagonism of N-methyl-D-aspartate receptors by sigma site ligands: potency, subtype-selectivity and mechanisms of inhibition.
Whittemore ER; Ilyin VI; Woodward RM
J Pharmacol Exp Ther; 1997 Jul; 282(1):326-38. PubMed ID: 9223571
[TBL] [Abstract][Full Text] [Related]
9. Evaluation of behavioural effects of a selective NMDA NR1A/2B receptor antagonist in the unilateral 6-OHDA lesion rat model.
Warraich ST; Allbutt HN; Billing R; Radford J; Coster MJ; Kassiou M; Henderson JM
Brain Res Bull; 2009 Feb; 78(2-3):85-90. PubMed ID: 18822357
[TBL] [Abstract][Full Text] [Related]
10. Behavioural effects of a selective NMDA NR1A/2B receptor antagonist in rats with unilateral 6-OHDA+parafascicular lesions.
Truong L; Allbutt HN; Coster MJ; Kassiou M; Henderson JM
Brain Res Bull; 2009 Feb; 78(2-3):91-6. PubMed ID: 19007866
[TBL] [Abstract][Full Text] [Related]
11. Discovery of (R)-1-[2-hydroxy-3-(4-hydroxy-phenyl)-propyl]-4-(4-methyl-benzyl)-piperidin-4-ol: a novel NR1/2B subtype selective NMDA receptor antagonist.
Pinard E; Alanine A; Bourson A; Büttelmann B; Gill R; Heitz M; Jaeschke G; Mutel V; Trube G; Wyler R
Bioorg Med Chem Lett; 2001 Aug; 11(16):2173-6. PubMed ID: 11514163
[TBL] [Abstract][Full Text] [Related]
12. Pharmacological characterization of Ro 63-1908 (1-[2-(4-hydroxy-phenoxy)-ethyl]-4-(4-methyl-benzyl)-piperidin-4-ol), a novel subtype-selective N-methyl-D-aspartate antagonist.
Gill R; Alanine A; Bourson A; Buttelmann B; Fischer G; Heitz MP; Kew JN; Levet-Trafit B; Lorez HP; Malherbe P; Miss MT; Mutel V; Pinard E; Roever S; Schmitt M; Trube G; Wybrecht R; Wyler R; Kemp JA
J Pharmacol Exp Ther; 2002 Sep; 302(3):940-8. PubMed ID: 12183650
[TBL] [Abstract][Full Text] [Related]
13. Characterization of haloperidol and trifluperidol as subtype-selective N-methyl-D-aspartate (NMDA) receptor antagonists using [3H]TCP and [3H]ifenprodil binding in rat brain membranes.
Coughenour LL; Cordon JJ
J Pharmacol Exp Ther; 1997 Feb; 280(2):584-92. PubMed ID: 9023267
[TBL] [Abstract][Full Text] [Related]
14. Structure-activity relationships of alkyl- and alkoxy-substituted 1,4-dihydroquinoxaline-2,3-diones: potent and systemically active antagonists for the glycine site of the NMDA receptor.
Cai SX; Kher SM; Zhou ZL; Ilyin V; Espitia SA; Tran M; Hawkinson JE; Woodward RM; Weber E; Keana JF
J Med Chem; 1997 Feb; 40(5):730-8. PubMed ID: 9057859
[TBL] [Abstract][Full Text] [Related]
15. Antagonist properties of the stereoisomers of ifenprodil at NR1A/NR2A and NR1A/NR2B subtypes of the NMDA receptor expressed in Xenopus oocytes.
Avenet P; Léonardon J; Besnard F; Graham D; Frost J; Depoortere H; Langer SZ; Scatton B
Eur J Pharmacol; 1996 Jan; 296(2):209-13. PubMed ID: 8838458
[TBL] [Abstract][Full Text] [Related]
16. Subtype-selective N-methyl-D-aspartate receptor antagonists: benzimidazalone and hydantoin as phenol replacements.
Schelkun RM; Yuen PW; Serpa K; Meltzer LT; Wise LD; Whittemore ER; Woodward RM
J Med Chem; 2000 May; 43(9):1892-7. PubMed ID: 10794706
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and pharmacological evaluation of N-(2,5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methylguanidines as N-methyl-D-aspartate receptor ion-channel blockers.
Hu LY; Guo J; Magar SS; Fischer JB; Burke-Howie KJ; Durant GJ
J Med Chem; 1997 Dec; 40(26):4281-9. PubMed ID: 9435897
[TBL] [Abstract][Full Text] [Related]
18. In vivo neurochemical effects of the NR2B selective NMDA receptor antagonist CR 3394 in 6-hydroxydopamine lesioned rats.
Sarre S; Lanza M; Makovec F; Artusi R; Caselli G; Michotte Y
Eur J Pharmacol; 2008 Apr; 584(2-3):297-305. PubMed ID: 18342306
[TBL] [Abstract][Full Text] [Related]
19. Discovery of subtype-selective NMDA receptor ligands: 4-benzyl-1-piperidinylalkynylpyrroles, pyrazoles and imidazoles as NR1A/2B antagonists.
Wright JL; Gregory TF; Boxer PA; Meltzer LT; Serpa KA; Wise LD
Bioorg Med Chem Lett; 1999 Oct; 9(19):2815-8. PubMed ID: 10522697
[TBL] [Abstract][Full Text] [Related]
20. Use of trifluoroperazine isolates a [(3)H]Ifenprodil binding site in rat brain membranes with the pharmacology of the voltage-independent ifenprodil site on N-methyl-D-aspartate receptors containing NR2B subunits.
Coughenour LL; Barr BM
J Pharmacol Exp Ther; 2001 Jan; 296(1):150-9. PubMed ID: 11123375
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]