146 related articles for article (PubMed ID: 10397244)
1. Role of O6-alkylguanine-DNA alkyltransferase in protecting against cyclophosphamide-induced toxicity and mutagenicity.
Cai Y; Wu MH; Ludeman SM; Grdina DJ; Dolan ME
Cancer Res; 1999 Jul; 59(13):3059-63. PubMed ID: 10397244
[TBL] [Abstract][Full Text] [Related]
2. Effect of O6-benzylguanine on alkylating agent-induced toxicity and mutagenicity. In Chinese hamster ovary cells expressing wild-type and mutant O6-alkylguanine-DNA alkyltransferases.
Cai Y; Wu MH; Xu-Welliver M; Pegg AE; Ludeman SM; Dolan ME
Cancer Res; 2000 Oct; 60(19):5464-9. PubMed ID: 11034089
[TBL] [Abstract][Full Text] [Related]
3. Modulation of cyclophosphamide activity by O6-alkylguanine-DNA alkyltransferase.
Friedman HS; Pegg AE; Johnson SP; Loktionova NA; Dolan ME; Modrich P; Moschel RC; Struck R; Brent TP; Ludeman S; Bullock N; Kilborn C; Keir S; Dong Q; Bigner DD; Colvin OM
Cancer Chemother Pharmacol; 1999; 43(1):80-5. PubMed ID: 9923545
[TBL] [Abstract][Full Text] [Related]
4. Molecular characterization of mutations in the hprt gene of normal human skin keratinocytes treated with N-ethyl-N-nitrosourea: influence of O6-alkylguanine alkyltransferase.
Tong HH; Park JH; Brady T; Weghorst CM; D'Ambrosio SM
Environ Mol Mutagen; 1997; 29(2):168-79. PubMed ID: 9118969
[TBL] [Abstract][Full Text] [Related]
5. Strand- and sequence-specific attenuation of N-methyl-N'-nitro-N-nitrosoguanidine-induced G.C to A.T transitions by expression of human 6-methylguanine-DNA methyltransferase in Chinese hamster ovary cells.
Yang JL; Hsieh FP; Lee PC; Tseng HJ
Cancer Res; 1994 Jul; 54(14):3857-63. PubMed ID: 8033107
[TBL] [Abstract][Full Text] [Related]
6. Effect of O6-benzylguanine on nitrogen mustard-induced toxicity, apoptosis, and mutagenicity in Chinese hamster ovary cells.
Cai Y; Ludeman SM; Wilson LR; Chung AB; Dolan ME
Mol Cancer Ther; 2001 Nov; 1(1):21-8. PubMed ID: 12467235
[TBL] [Abstract][Full Text] [Related]
7. Effect of acrolein on phosphoramide mustard-induced sister chromatid exchanges in cultured human lymphocytes.
Wilmer JL; Erexson GL; Kligerman AD
Cancer Res; 1990 Aug; 50(15):4635-8. PubMed ID: 2369740
[TBL] [Abstract][Full Text] [Related]
8. Toxicity, mutagenicity, and mutational spectra of N-ethyl-N-nitrosourea in human cell lines with different DNA repair phenotypes.
Bronstein SM; Cochrane JE; Craft TR; Swenberg JA; Skopek TR
Cancer Res; 1991 Oct; 51(19):5188-97. PubMed ID: 1655249
[TBL] [Abstract][Full Text] [Related]
9. 1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(methylamino)carbonyl]hydrazine (VNP40101M): II. Role of O6-alkylguanine-DNA alkyltransferase in cytotoxicity.
Baumann RP; Shyam K; Penketh PG; Remack JS; Brent TP; Sartorelli AC
Cancer Chemother Pharmacol; 2004 Apr; 53(4):288-95. PubMed ID: 14685775
[TBL] [Abstract][Full Text] [Related]
10. Effect of alterations of key active site residues in O6-alkylguanine-DNA Alkyltransferase on its ability to modulate the genotoxicity of 1,2-dibromoethane.
Liu L; Watanabe K; Fang Q; Williams KM; Guengerich FP; Pegg AE
Chem Res Toxicol; 2007 Jan; 20(1):155-63. PubMed ID: 17226938
[TBL] [Abstract][Full Text] [Related]
11. Function of domains of human O6-alkylguanine-DNA alkyltransferase.
Fang Q; Kanugula S; Pegg AE
Biochemistry; 2005 Nov; 44(46):15396-405. PubMed ID: 16285744
[TBL] [Abstract][Full Text] [Related]
12. Cytotoxicity and DNA cross-linking activity of 4-sulfidocyclophosphamides in mouse leukemia cells in vitro.
Erickson LC; Ramonas LM; Zaharko DS; Kohn KW
Cancer Res; 1980 Nov; 40(11):4216-20. PubMed ID: 7471062
[TBL] [Abstract][Full Text] [Related]
13. Role of O6-alkylguanine-DNA alkyltransferase in protecting against 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-induced long-term toxicities.
Hansen RJ; Nagasubramanian R; Delaney SM; Cherian MM; Lin S; Kogan SC; Dolan ME
J Pharmacol Exp Ther; 2005 Dec; 315(3):1247-55. PubMed ID: 16126841
[TBL] [Abstract][Full Text] [Related]
14. Attenuation of cytogenetic damage by 2-mercaptoethanesulfonate in cultured human lymphocytes exposed to cyclophosphamide and its reactive metabolites.
Wilmer JL; Erexson GL; Kligerman AD
Cancer Res; 1986 Jan; 46(1):203-10. PubMed ID: 3079586
[TBL] [Abstract][Full Text] [Related]
15. O6-pyridyloxobutylguanine adducts contribute to the mutagenic properties of pyridyloxobutylating agents.
Mijal RS; Loktionova NA; Vu CC; Pegg AE; Peterson LA
Chem Res Toxicol; 2005 Oct; 18(10):1619-25. PubMed ID: 16533027
[TBL] [Abstract][Full Text] [Related]
16. Engineering substrate specificity of O6-alkylguanine-DNA alkyltransferase for specific protein labeling in living cells.
Juillerat A; Heinis C; Sielaff I; Barnikow J; Jaccard H; Kunz B; Terskikh A; Johnsson K
Chembiochem; 2005 Jul; 6(7):1263-9. PubMed ID: 15934048
[TBL] [Abstract][Full Text] [Related]
17. Effects of phosphoramide mustard and acrolein, cytotoxic metabolites of cyclophosphamide, on mouse limb development in vitro.
Hales BF
Teratology; 1989 Jul; 40(1):11-20. PubMed ID: 2763206
[TBL] [Abstract][Full Text] [Related]
18. O6-alkylguanine-DNA alkyltransferase has opposing effects in modulating the genotoxicity of dibromomethane and bromomethyl acetate.
Liu L; Williams KM; Guengerich FP; Pegg AE
Chem Res Toxicol; 2004 Jun; 17(6):742-52. PubMed ID: 15206895
[TBL] [Abstract][Full Text] [Related]
19. Role of MGMT in protecting against cyclophosphamide-induced toxicity in cells and animals.
Hansen RJ; Ludeman SM; Paikoff SJ; Pegg AE; Dolan ME
DNA Repair (Amst); 2007 Aug; 6(8):1145-54. PubMed ID: 17485251
[TBL] [Abstract][Full Text] [Related]
20. Inactivation and degradation of O(6)-alkylguanine-DNA alkyltransferase after reaction with nitric oxide.
Liu L; Xu-Welliver M; Kanugula S; Pegg AE
Cancer Res; 2002 Jun; 62(11):3037-43. PubMed ID: 12036910
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
