These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 10397500)

  • 1. Design and synthesis of 2-[4-[4-(m-(ethylsulfonamido)-phenyl) piperazin-1-yl]butyl]-1,3-dioxoperhydropyrrolo[1,2-c]imidazole (EF-7412) using neural networks. A selective derivative with mixed 5-HT1A/D2 antagonist properties.
    López-Rodríguez ML; Morcillo MJ; Fernández E; Rosado ML; Orensanz L; Beneytez ME; Manzanares J; Fuentes JA; Schaper KJ
    Bioorg Med Chem Lett; 1999 Jun; 9(12):1679-82. PubMed ID: 10397500
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and structure-activity relationships of a new model of arylpiperazines. 5. Study of the physicochemical influence of the pharmacophore on 5-HT(1a)/alpha(1)-adrenergic receptor affinity: synthesis of a new derivative with mixed 5-HT(1a)/d(2) antagonist properties.
    López-Rodríguez ML; Morcillo MJ; Fernández E; Porras E; Orensanz L; Beneytez ME; Manzanares J; Fuentes JA
    J Med Chem; 2001 Jan; 44(2):186-97. PubMed ID: 11170628
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and structure-activity relationships of a new model of arylpiperazines. Study of the 5-HT(1a)/alpha(1)-adrenergic receptor affinity by classical hansch analysis, artificial neural networks, and computational simulation of ligand recognition.
    López-Rodríguez ML; Morcillo MJ; Fernández E; Rosado ML; Pardo L; Schaper K
    J Med Chem; 2001 Jan; 44(2):198-207. PubMed ID: 11170629
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Spiperone: influence of spiro ring substituents on 5-HT2A serotonin receptor binding.
    Metwally KA; Dukat M; Egan CT; Smith C; DuPre A; Gauthier CB; Herrick-Davis K; Teitler M; Glennon RA
    J Med Chem; 1998 Dec; 41(25):5084-93. PubMed ID: 9836624
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and pharmacological evaluation of 1-[(1,2-diphenyl-1H-4-imidazolyl)methyl]-4-phenylpiperazines with clozapine-like mixed activities at dopamine D(2), serotonin, and GABA(A) receptors.
    Asproni B; Pau A; Bitti M; Melosu M; Cerri R; Dazzi L; Seu E; Maciocco E; Sanna E; Busonero F; Talani G; Pusceddu L; Altomare C; Trapani G; Biggio G
    J Med Chem; 2002 Oct; 45(21):4655-68. PubMed ID: 12361392
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and structure-activity relationships of a new model of arylpiperazines. 4. 1-[omega-(4-Arylpiperazin-1-yl)alkyl]-3-(diphenylmethylene) - 2, 5-pyrrolidinediones and -3-(9H-fluoren-9-ylidene)-2, 5-pyrrolidinediones: study of the steric requirements of the terminal amide fragment on 5-HT1A affinity/selectivity.
    López-Rodríguez ML; Morcillo MJ; Rovat TK; Fernández E; Vicente B; Sanz AM; Hernández M; Orensanz L
    J Med Chem; 1999 Jan; 42(1):36-49. PubMed ID: 9888831
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and 5-HT3 receptor affinity of new quinolinecarboxylic acid derivatives.
    Orjales A; Alonso-Cires L; López-Tudanca PL; Tapia I; Labeaga L; Mosquera R
    Drug Des Discov; 2000; 16(4):271-9. PubMed ID: 10807033
    [TBL] [Abstract][Full Text] [Related]  

  • 8. (S)-(-)-4-[4-[2-(isochroman-1-yl)ethyl]-piperazin-1-yl] benzenesulfonamide, a selective dopamine D4 antagonist.
    TenBrink RE; Bergh CL; Duncan JN; Harris DW; Huff RM; Lahti RA; Lawson CF; Lutzke BS; Martin IJ; Rees SA; Schlachter SK; Sih JC; Smith MW
    J Med Chem; 1996 Jun; 39(13):2435-7. PubMed ID: 8691438
    [No Abstract]   [Full Text] [Related]  

  • 9. Analogues of the potential antipsychotic agent 1192U90: amide modifications.
    Navas F; Tang FL; Schaller LT; Norman MH
    Bioorg Med Chem; 1998 Jun; 6(6):811-23. PubMed ID: 9681147
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis, 5-HT1A and 5-HT2A receptor activity of new 1-phenylpiperazinylpropyl derivatives with arylalkyl substituents in position 7 of purine-2,6-dione.
    Chloń G; Pawłowski M; Duszyńska B; Szaro A; Tatarczńska E; Kłodzińska AL; Chojnacka-Wójcik E
    Pol J Pharmacol; 2001; 53(4):359-68. PubMed ID: 11990082
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The impact of the halogen bonding on D
    Partyka A; Kurczab R; Canale V; Satała G; Marciniec K; Pasierb A; Jastrzębska-Więsek M; Pawłowski M; Wesołowska A; Bojarski AJ; Zajdel P
    Bioorg Med Chem; 2017 Jul; 25(14):3638-3648. PubMed ID: 28529043
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and structure-activity relationships of 4-amino-5-chloro-N-(1,4-dialkylhexahydro-1,4-diazepin-6-yl)-2-methoxybenzamide derivatives, novel and potent serotonin 5-HT3 and dopamine D2 receptors dual antagonist.
    Hirokawa Y; Harada H; Yoshikawa T; Yoshida N; Kato S
    Chem Pharm Bull (Tokyo); 2002 Jul; 50(7):941-59. PubMed ID: 12130853
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enhanced D1 affinity in a series of piperazine ring substituted 1-piperazino-3-arylindans with potential atypical antipsychotic activity.
    Bøgesø KP; Arnt J; Frederiksen K; Hansen HO; Hyttel J; Pedersen H
    J Med Chem; 1995 Oct; 38(22):4380-92. PubMed ID: 7473566
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and structure-activity relationships of a new model of arylpiperazines. 1. 2-[[4-(o-methoxyphenyl)piperazin-1-yl]methyl]-1, 3-dioxoperhydroimidazo[1,5-alpha]pyridine: a selective 5-HT1A receptor agonist.
    López-Rodríguez ML; Rosado ML; Benhamú B; Morcillo MJ; Sanz AM; Orensanz L; Beneitez ME; Fuentes JA; Manzanares J
    J Med Chem; 1996 Oct; 39(22):4439-50. PubMed ID: 8893838
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and structure-affinity relationships of novel N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6-yl)pyridine-3-carboxamides with potent serotonin 5-HT3 and dopamine D2 receptor antagonistic activity.
    Hirokawa Y; Fujiwara I; Suzuki K; Harada H; Yoshikawa T; Yoshida N; Kato S
    J Med Chem; 2003 Feb; 46(5):702-15. PubMed ID: 12593651
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 1-Substituted-4-[3-(1,2,3,4-tetrahydro-5- or 7-methoxynaphthalen-1-yl)propyl]piperazines: influence of the N-1 piperazine substituent on 5-HT1A receptor affinity and selectivity versus D2 and alpha1 receptors. Part 6.
    Perrone R; Berardi F; Colabufo NA; Leopoldo M; Tortorella V
    Bioorg Med Chem; 2000 May; 8(5):873-81. PubMed ID: 10881999
    [TBL] [Abstract][Full Text] [Related]  

  • 17. trans-4-[4-(Methoxyphenyl)cyclohexyl]-1-arylpiperazines: a new class of potent and selective 5-HT(1A) receptor ligands as conformationally constrained analogues of 4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]-1-arylpiperazines.
    Perrone R; Berardi F; Colabufo NA; Leopoldo M; Lacivita E; Tortorella V; Leonardi A; Poggesi E; Testa R
    J Med Chem; 2001 Dec; 44(25):4431-42. PubMed ID: 11728188
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 1,2,5-Thiadiazole derivatives are potent and selective ligands at human 5-HT1A receptors.
    Sabb AL; Vogel RL; Kelly MG; Palmer Y; Smith DL; Andree TH; Schechter LE
    Bioorg Med Chem Lett; 2001 Apr; 11(8):1069-71. PubMed ID: 11327592
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bicyclic piperazinylbenzenesulphonamides are potent and selective 5-HT6 receptor antagonists.
    Bromidge SM; Clarke SE; King FD; Lovell PJ; Newman H; Riley G; Routledge C; Serafinowska HT; Smith DR; Thomas DR
    Bioorg Med Chem Lett; 2002 May; 12(10):1357-60. PubMed ID: 11992776
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-activity relationship studies of CNS agents. Part 38. Novel 1,4-benzoxazin-3(4H)-one, 1,2-benzoxazolin-3-one and 1,3-benzoxazolin-2,4-dione arylpiperazine derivatives with different 5-HT1A and antagonistic 5-HT2A activities.
    Mokrosz MJ; Kowalski P; Kowalska T; Majka Z; Duszyńska B; Bojarski AJ; Fruziński A; Karolak-Wojciechowska J; Wesołowska A; Kłodzińska A; Tatarczyńska E; Chojnacka-Wójcik E
    Arch Pharm (Weinheim); 1999 Nov; 332(11):373-9. PubMed ID: 10605377
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.