418 related articles for article (PubMed ID: 10404513)
1. C-terminal maturation fragments of presenilin 1 and 2 control secretion of APP alpha and A beta by human cells and are degraded by proteasome.
da Costa CA; Ancolio K; Checler F
Mol Med; 1999 Mar; 5(3):160-8. PubMed ID: 10404513
[TBL] [Abstract][Full Text] [Related]
2. Alzheimer's disease-linked mutation of presenilin 2 (N141I-PS2) drastically lowers APPalpha secretion: control by the proteasome.
Marambaud P; Alves da Costa C; Ancolio K; Checler F
Biochem Biophys Res Commun; 1998 Nov; 252(1):134-8. PubMed ID: 9813158
[TBL] [Abstract][Full Text] [Related]
3. Proteasome inhibitors prevent the degradation of familial Alzheimer's disease-linked presenilin 1 and potentiate A beta 42 recovery from human cells.
Marambaud P; Ancolio K; Lopez-Perez E; Checler F
Mol Med; 1998 Mar; 4(3):147-57. PubMed ID: 9562973
[TBL] [Abstract][Full Text] [Related]
4. Dual roles of proteasome in the metabolism of presenilin 1.
Honda T; Yasutake K; Nihonmatsu N; Mercken M; Takahashi H; Murayama O; Murayama M; Sato K; Omori A; Tsubuki S; Saido TC; Takashima A
J Neurochem; 1999 Jan; 72(1):255-61. PubMed ID: 9886077
[TBL] [Abstract][Full Text] [Related]
5. Constitutive and protein kinase C-regulated secretory cleavage of Alzheimer's beta-amyloid precursor protein: different control of early and late events by the proteasome.
Marambaud P; Lopez-Perez E; Wilk S; Checler F
J Neurochem; 1997 Dec; 69(6):2500-5. PubMed ID: 9375683
[TBL] [Abstract][Full Text] [Related]
6. Endoproteolytic cleavage and proteasomal degradation of presenilin 2 in transfected cells.
Kim TW; Pettingell WH; Hallmark OG; Moir RD; Wasco W; Tanzi RE
J Biol Chem; 1997 Apr; 272(17):11006-10. PubMed ID: 9110991
[TBL] [Abstract][Full Text] [Related]
7. gamma-Secretase complexes containing N- and C-terminal fragments of different presenilin origin retain normal gamma-secretase activity.
Strömberg K; Hansson EM; Laudon H; Bergstedt S; Näslund J; Lundkvist J; Lendahl U
J Neurochem; 2005 Nov; 95(3):880-90. PubMed ID: 16135086
[TBL] [Abstract][Full Text] [Related]
8. Regulation of amyloid precursor protein processing by presenilin 1 (PS1) and PS2 in PS1 knockout cells.
Palacino JJ; Berechid BE; Alexander P; Eckman C; Younkin S; Nye JS; Wolozin B
J Biol Chem; 2000 Jan; 275(1):215-22. PubMed ID: 10617607
[TBL] [Abstract][Full Text] [Related]
9. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
Xia W; Zhang J; Ostaszewski BL; Kimberly WT; Seubert P; Koo EH; Shen J; Selkoe DJ
Biochemistry; 1998 Nov; 37(47):16465-71. PubMed ID: 9843412
[TBL] [Abstract][Full Text] [Related]
10. Endoproteolysis of presenilin in vitro: inhibition by gamma-secretase inhibitors.
Campbell WA; Iskandar MK; Reed ML; Xia W
Biochemistry; 2002 Mar; 41(10):3372-9. PubMed ID: 11876645
[TBL] [Abstract][Full Text] [Related]
11. Evidence that enzyme processivity mediates differential Aβ production by PS1 and PS2.
Pintchovski SA; Schenk DB; Basi GS
Curr Alzheimer Res; 2013 Jan; 10(1):4-10. PubMed ID: 22950863
[TBL] [Abstract][Full Text] [Related]
12. Subcellular localization of presenilin 2 endoproteolytic C-terminal fragments.
Tekirian TL; Merriam DE; Marshansky V; Miller J; Crowley AC; Chan H; Ausiello D; Brown D; Buxbaum JD; Xia W; Wasco W
Brain Res Mol Brain Res; 2001 Nov; 96(1-2):14-20. PubMed ID: 11731004
[TBL] [Abstract][Full Text] [Related]
13. A distinct ER/IC gamma-secretase competes with the proteasome for cleavage of APP.
Skovronsky DM; Pijak DS; Doms RW; Lee VM
Biochemistry; 2000 Feb; 39(4):810-7. PubMed ID: 10651647
[TBL] [Abstract][Full Text] [Related]
14. Inhibiting amyloid precursor protein C-terminal cleavage promotes an interaction with presenilin 1.
Verdile G; Martins RN; Duthie M; Holmes E; St George-Hyslop PH; Fraser PE
J Biol Chem; 2000 Jul; 275(27):20794-8. PubMed ID: 10801777
[TBL] [Abstract][Full Text] [Related]
15. The transmembrane aspartates in presenilin 1 and 2 are obligatory for gamma-secretase activity and amyloid beta-protein generation.
Kimberly WT; Xia W; Rahmati T; Wolfe MS; Selkoe DJ
J Biol Chem; 2000 Feb; 275(5):3173-8. PubMed ID: 10652302
[TBL] [Abstract][Full Text] [Related]
16. Mapping the APP/presenilin (PS) binding domains: the hydrophilic N-terminus of PS2 is sufficient for interaction with APP and can displace APP/PS1 interaction.
Pradier L; Carpentier N; Delalonde L; Clavel N; Bock MD; Buée L; Mercken L; Tocqué B; Czech C
Neurobiol Dis; 1999 Feb; 6(1):43-55. PubMed ID: 10078972
[TBL] [Abstract][Full Text] [Related]
17. PS1 N- and C-terminal fragments form a complex that functions in APP processing and Notch signaling.
Levitan D; Lee J; Song L; Manning R; Wong G; Parker E; Zhang L
Proc Natl Acad Sci U S A; 2001 Oct; 98(21):12186-90. PubMed ID: 11593035
[TBL] [Abstract][Full Text] [Related]
18. Ubiquilin regulates presenilin endoproteolysis and modulates gamma-secretase components, Pen-2 and nicastrin.
Massey LK; Mah AL; Monteiro MJ
Biochem J; 2005 Nov; 391(Pt 3):513-25. PubMed ID: 15975090
[TBL] [Abstract][Full Text] [Related]
19. Expression of Alzheimer's disease-associated presenilin-1 is controlled by proteolytic degradation and complex formation.
Steiner H; Capell A; Pesold B; Citron M; Kloetzel PM; Selkoe DJ; Romig H; Mendla K; Haass C
J Biol Chem; 1998 Nov; 273(48):32322-31. PubMed ID: 9822712
[TBL] [Abstract][Full Text] [Related]
20. Enhanced production and oligomerization of the 42-residue amyloid beta-protein by Chinese hamster ovary cells stably expressing mutant presenilins.
Xia W; Zhang J; Kholodenko D; Citron M; Podlisny MB; Teplow DB; Haass C; Seubert P; Koo EH; Selkoe DJ
J Biol Chem; 1997 Mar; 272(12):7977-82. PubMed ID: 9065468
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
