BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

770 related articles for article (PubMed ID: 10404514)

  • 1. Transgenic mice expressing Shb adaptor protein under the control of rat insulin promoter exhibit altered viability of pancreatic islet cells.
    Welsh M; Christmansson L; Karlsson T; Sandler S; Welsh N
    Mol Med; 1999 Mar; 5(3):169-80. PubMed ID: 10404514
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dual role of the tyrosine kinase GTK and the adaptor protein SHB in beta-cell growth: enhanced beta-cell replication after 60% pancreatectomy and increased sensitivity to streptozotocin.
    Annerén C
    J Endocrinol; 2002 Jan; 172(1):145-53. PubMed ID: 11786382
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Increased cytokine-induced cytotoxicity of pancreatic islet cells from transgenic mice expressing the Src-like tyrosine kinase GTK.
    Annerén C; Welsh M
    Mol Med; 2001 May; 7(5):301-10. PubMed ID: 11474576
    [TBL] [Abstract][Full Text] [Related]  

  • 4. GTK tyrosine kinase-induced alteration of IRS-protein signalling in insulin producing cells.
    Annerén C; Welsh M
    Mol Med; 2002 Nov; 8(11):705-13. PubMed ID: 12520087
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Overexpression of the Shb SH2 domain-protein in insulin-producing cells leads to altered signaling through the IRS-1 and IRS-2 proteins.
    Welsh N; Makeeva N; Welsh M
    Mol Med; 2002 Nov; 8(11):695-704. PubMed ID: 12520086
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Impaired glucose homeostasis in Shb-/- mice.
    Akerblom B; Barg S; Calounova G; Mokhtari D; Jansson L; Welsh M
    J Endocrinol; 2009 Nov; 203(2):271-9. PubMed ID: 19696098
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma.
    Hong TP; Andersen NA; Nielsen K; Karlsen AE; Fantuzzi G; Eizirik DL; Dinarello CA; Mandrup-Poulsen T
    Eur Cytokine Netw; 2000 Jun; 11(2):193-205. PubMed ID: 10903798
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pancreatic islets from cyclin-dependent kinase 4/R24C (Cdk4) knockin mice have significantly increased beta cell mass and are physiologically functional, indicating that Cdk4 is a potential target for pancreatic beta cell mass regeneration in Type 1 diabetes.
    Marzo N; Mora C; Fabregat ME; Martín J; Usac EF; Franco C; Barbacid M; Gomis R
    Diabetologia; 2004 Apr; 47(4):686-94. PubMed ID: 15298346
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets.
    Alenkvist I; Dyachok O; Tian G; Li J; Mehrabanfar S; Jin Y; Birnir B; Tengholm A; Welsh M
    J Endocrinol; 2014 Dec; 223(3):267-75. PubMed ID: 25274988
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interleukin-1 plus gamma-interferon-induced pancreatic beta-cell dysfunction is mediated by beta-cell nitric oxide production.
    Thomas HE; Darwiche R; Corbett JA; Kay TW
    Diabetes; 2002 Feb; 51(2):311-6. PubMed ID: 11812737
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In vivo proliferation of differentiated pancreatic islet beta cells in transgenic mice expressing mutated cyclin-dependent kinase 4.
    Hino S; Yamaoka T; Yamashita Y; Yamada T; Hata J; Itakura M
    Diabetologia; 2004 Oct; 47(10):1819-30. PubMed ID: 15480536
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes.
    Devedjian JC; George M; Casellas A; Pujol A; Visa J; Pelegrín M; Gros L; Bosch F
    J Clin Invest; 2000 Mar; 105(6):731-40. PubMed ID: 10727441
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Glucose intolerance and reduced islet blood flow in transgenic mice expressing the FRK tyrosine kinase under the control of the rat insulin promoter.
    Annerén C; Welsh M; Jansson L
    Am J Physiol Endocrinol Metab; 2007 Apr; 292(4):E1183-90. PubMed ID: 17179392
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Overexpression of PACAP in transgenic mouse pancreatic beta-cells enhances insulin secretion and ameliorates streptozotocin-induced diabetes.
    Yamamoto K; Hashimoto H; Tomimoto S; Shintani N; Miyazaki J; Tashiro F; Aihara H; Nammo T; Li M; Yamagata K; Miyagawa J; Matsuzawa Y; Kawabata Y; Fukuyama Y; Koga K; Mori W; Tanaka K; Matsuda T; Baba A
    Diabetes; 2003 May; 52(5):1155-62. PubMed ID: 12716746
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Overexpression of GPR40 in pancreatic beta-cells augments glucose-stimulated insulin secretion and improves glucose tolerance in normal and diabetic mice.
    Nagasumi K; Esaki R; Iwachidow K; Yasuhara Y; Ogi K; Tanaka H; Nakata M; Yano T; Shimakawa K; Taketomi S; Takeuchi K; Odaka H; Kaisho Y
    Diabetes; 2009 May; 58(5):1067-76. PubMed ID: 19401434
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Aged transgenic mice with increased glucocorticoid sensitivity in pancreatic beta-cells develop diabetes.
    Davani B; Portwood N; Bryzgalova G; Reimer MK; Heiden T; Ostenson CG; Okret S; Ahren B; Efendic S; Khan A
    Diabetes; 2004 Feb; 53 Suppl 1():S51-9. PubMed ID: 14749266
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of poly (ADP-ribose) synthetase by gene disruption or inhibition with 5-iodo-6-amino-1,2-benzopyrone protects mice from multiple-low-dose-streptozotocin-induced diabetes.
    Mabley JG; Suarez-Pinzon WL; Haskó G; Salzman AL; Rabinovitch A; Kun E; Szabó C
    Br J Pharmacol; 2001 Jul; 133(6):909-19. PubMed ID: 11454665
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cytokine-induced inhibition of insulin release from mouse pancreatic beta-cells deficient in inducible nitric oxide synthase.
    Andersson AK; Flodström M; Sandler S
    Biochem Biophys Res Commun; 2001 Feb; 281(2):396-403. PubMed ID: 11181061
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice.
    Bao S; Jacobson DA; Wohltmann M; Bohrer A; Jin W; Philipson LH; Turk J
    Am J Physiol Endocrinol Metab; 2008 Feb; 294(2):E217-29. PubMed ID: 17895289
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Low dose streptozotocin-induced diabetes in rat insulin promoter-mCD80-transgenic mice is T cell autoantigen-specific and CD28 dependent.
    Pechhold K; Patterson NB; Blum C; Fleischacker CL; Boehm BO; Harlan DM
    J Immunol; 2001 Feb; 166(4):2531-9. PubMed ID: 11160314
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 39.