BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

618 related articles for article (PubMed ID: 10409402)

  • 21. Roles of NADPH-P450 reductase in the O-deethylation of 7-ethoxycoumarin by recombinant human cytochrome P450 1B1 variants in Escherichia coli.
    Shimada T; Tsumura F; Gillam EM; Guengerich FP; Inoue K
    Protein Expr Purif; 2000 Oct; 20(1):73-80. PubMed ID: 11035953
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Arylhydrocarbon receptor-dependent induction of liver and lung cytochromes P450 1A1, 1A2, and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in genetically engineered C57BL/6J mice.
    Shimada T; Inoue K; Suzuki Y; Kawai T; Azuma E; Nakajima T; Shindo M; Kurose K; Sugie A; Yamagishi Y; Fujii-Kuriyama Y; Hashimoto M
    Carcinogenesis; 2002 Jul; 23(7):1199-207. PubMed ID: 12117779
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Bioactivation of diesel exhaust particle extracts and their major nitrated polycyclic aromatic hydrocarbon components, 1-nitropyrene and dinitropyrenes, by human cytochromes P450 1A1, 1A2, and 1B1.
    Yamazaki H; Hatanaka N; Kizu R; Hayakawa K; Shimada N; Guengerich FP; Nakajima M; Yokoi T
    Mutat Res; 2000 Dec; 472(1-2):129-38. PubMed ID: 11113705
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Benzo[a]pyrene metabolism by purified cytochrome P-450 from 3-methylcholanthrene-treated rats.
    Sagami I; Ohmachi T; Fujii H; Watanabe M
    Xenobiotica; 1987 Feb; 17(2):189-98. PubMed ID: 3564534
    [TBL] [Abstract][Full Text] [Related]  

  • 25. A new selective and potent inhibitor of human cytochrome P450 1B1 and its application to antimutagenesis.
    Chun YJ; Kim S; Kim D; Lee SK; Guengerich FP
    Cancer Res; 2001 Nov; 61(22):8164-70. PubMed ID: 11719446
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase.
    Oda Y; Aryal P; Terashita T; Gillam EM; Guengerich FP; Shimada T
    Mutat Res; 2001 May; 492(1-2):81-90. PubMed ID: 11377247
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The K-region trans-8,9-diol does not significantly contribute as an intermediate in the metabolic activation of dibenzo[a,l]pyrene to DNA-binding metabolites by human cytochrome P450 1A1 or 1B1.
    Luch A; Kishiyama S; Seidel A; Doehmer J; Greim H; Baird WM
    Cancer Res; 1999 Sep; 59(18):4603-9. PubMed ID: 10493514
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Specificity of 17beta-oestradiol and benzo[a]pyrene oxidation by polymorphic human cytochrome P4501B1 variants substituted at residues 48, 119 and 432.
    Shimada T; Watanabe J; Inoue K; Guengerich FP; Gillam EM
    Xenobiotica; 2001 Mar; 31(3):163-76. PubMed ID: 11465393
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Engineered yeast cells as model to study coupling between human xenobiotic metabolizing enzymes. Simulation of the two first steps of benzo[a]pyrene activation.
    Gautier JC; Urban P; Beaune P; Pompon D
    Eur J Biochem; 1993 Jan; 211(1-2):63-72. PubMed ID: 8425552
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Cell-catalyzed binding of 3H-(-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene to cellular and exogenous DNA and the role of purified human liver epoxide hydrolase.
    Gozakara EM; Guengerich FP; Gelboin HV
    Pharmacology; 1988; 37(3):154-64. PubMed ID: 3227049
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Genotoxic activation of benzophenone and its two metabolites by human cytochrome P450s in SOS/umu assay.
    Takemoto K; Yamazaki H; Nakajima M; Yokoi T
    Mutat Res; 2002 Aug; 519(1-2):199-204. PubMed ID: 12160905
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers.
    Šulc M; Indra R; Moserová M; Schmeiser HH; Frei E; Arlt VM; Stiborová M
    Environ Mol Mutagen; 2016 Apr; 57(3):229-35. PubMed ID: 26919089
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Expression and characterization of four recombinant human dihydrodiol dehydrogenase isoforms: oxidation of trans-7, 8-dihydroxy-7,8-dihydrobenzo[a]pyrene to the activated o-quinone metabolite benzo[a]pyrene-7,8-dione.
    Burczynski ME; Harvey RG; Penning TM
    Biochemistry; 1998 May; 37(19):6781-90. PubMed ID: 9578563
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Stereoselective epoxidation and hydration at the K-region of polycyclic aromatic hydrocarbons by cDNA-expressed cytochromes P450 1A1, 1A2, and epoxide hydrolase.
    Shou M; Gonzalez FJ; Gelboin HV
    Biochemistry; 1996 Dec; 35(49):15807-13. PubMed ID: 8961944
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Recombinant human cytochrome P450 1B1 expression in Escherichia coli.
    Shimada T; Wunsch RM; Hanna IH; Sutter TR; Guengerich FP; Gillam EM
    Arch Biochem Biophys; 1998 Sep; 357(1):111-20. PubMed ID: 9721189
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Polycyclic aromatic hydrocarbons stimulate human CYP3A4 promoter activity via PXR.
    Luckert C; Ehlers A; Buhrke T; Seidel A; Lampen A; Hessel S
    Toxicol Lett; 2013 Oct; 222(2):180-8. PubMed ID: 23845848
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Characterization of human lung microsomal cytochrome P-450 1A1 and its role in the oxidation of chemical carcinogens.
    Shimada T; Yun CH; Yamazaki H; Gautier JC; Beaune PH; Guengerich FP
    Mol Pharmacol; 1992 May; 41(5):856-64. PubMed ID: 1588920
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Effects of butylated hydroxyanisole on the metabolism of benzo(a)pyrene by mouse lung microsomes.
    Sydor W; Lewis KF; Yang CS
    Cancer Res; 1984 Jan; 44(1):134-8. PubMed ID: 6317167
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Aryl acetylenes as mechanism-based inhibitors of cytochrome P450-dependent monooxygenase enzymes.
    Foroozesh M; Primrose G; Guo Z; Bell LC; Alworth WL; Guengerich FP
    Chem Res Toxicol; 1997 Jan; 10(1):91-102. PubMed ID: 9074808
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Comparative metabolism of the aza polynuclear aromatic hydrocarbon dibenz[a,h]acridine by recombinant human and rat cytochrome P450s.
    Yuan ZX; Kumar S; Sikka HC
    Chem Res Toxicol; 2004 May; 17(5):672-8. PubMed ID: 15144224
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 31.