196 related articles for article (PubMed ID: 10411488)
1. 2,7-Disubstituted amidofluorenone derivatives as inhibitors of human telomerase.
Perry PJ; Read MA; Davies RT; Gowan SM; Reszka AP; Wood AA; Kelland LR; Neidle S
J Med Chem; 1999 Jul; 42(14):2679-84. PubMed ID: 10411488
[TBL] [Abstract][Full Text] [Related]
2. Human telomerase inhibition by regioisomeric disubstituted amidoanthracene-9,10-diones.
Perry PJ; Reszka AP; Wood AA; Read MA; Gowan SM; Dosanjh HS; Trent JO; Jenkins TC; Kelland LR; Neidle S
J Med Chem; 1998 Nov; 41(24):4873-84. PubMed ID: 9822556
[TBL] [Abstract][Full Text] [Related]
3. 1,4- and 2,6-disubstituted amidoanthracene-9,10-dione derivatives as inhibitors of human telomerase.
Perry PJ; Gowan SM; Reszka AP; Polucci P; Jenkins TC; Kelland LR; Neidle S
J Med Chem; 1998 Aug; 41(17):3253-60. PubMed ID: 9703471
[TBL] [Abstract][Full Text] [Related]
4. Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors.
Read M; Harrison RJ; Romagnoli B; Tanious FA; Gowan SH; Reszka AP; Wilson WD; Kelland LR; Neidle S
Proc Natl Acad Sci U S A; 2001 Apr; 98(9):4844-9. PubMed ID: 11309493
[TBL] [Abstract][Full Text] [Related]
5. Activation of human telomerase reverse transcriptase expression by some new symmetrical bis-substituted derivatives of the anthraquinone.
Huang HS; Chiou JF; Fong Y; Hou CC; Lu YC; Wang JY; Shih JW; Pan YR; Lin JJ
J Med Chem; 2003 Jul; 46(15):3300-7. PubMed ID: 12852760
[TBL] [Abstract][Full Text] [Related]
6. Effects of cationic porphyrins as G-quadruplex interactive agents in human tumor cells.
Izbicka E; Wheelhouse RT; Raymond E; Davidson KK; Lawrence RA; Sun D; Windle BE; Hurley LH; Von Hoff DD
Cancer Res; 1999 Feb; 59(3):639-44. PubMed ID: 9973212
[TBL] [Abstract][Full Text] [Related]
7. Rational design, synthesis, biophysical and antiproliferative evaluation of fluorenone derivatives with DNA G-quadruplex binding properties.
Alcaro S; Artese A; Iley JN; Missailidis S; Ortuso F; Parrotta L; Pasceri R; Paduano F; Sissi C; Trapasso F; Vigorita MG
ChemMedChem; 2010 Apr; 5(4):575-83. PubMed ID: 20135671
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and evaluation of quindoline derivatives as G-quadruplex inducing and stabilizing ligands and potential inhibitors of telomerase.
Zhou JL; Lu YJ; Ou TM; Zhou JM; Huang ZS; Zhu XF; Du CJ; Bu XZ; Ma L; Gu LQ; Li YM; Chan AS
J Med Chem; 2005 Nov; 48(23):7315-21. PubMed ID: 16279791
[TBL] [Abstract][Full Text] [Related]
9. Rational design of acridine-based ligands with selectivity for human telomeric quadruplexes.
Sparapani S; Haider SM; Doria F; Gunaratnam M; Neidle S
J Am Chem Soc; 2010 Sep; 132(35):12263-72. PubMed ID: 20718414
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis, and biological evaluation of a series of fluoroquinoanthroxazines with contrasting dual mechanisms of action against topoisomerase II and G-quadruplexes.
Kim MY; Duan W; Gleason-Guzman M; Hurley LH
J Med Chem; 2003 Feb; 46(4):571-83. PubMed ID: 12570378
[TBL] [Abstract][Full Text] [Related]
11. Synthesis, human telomerase inhibition and anti-proliferative studies of a series of 2,7-bis-substituted amido-anthraquinone derivatives.
Huang HS; Huang KF; Li CL; Huang YY; Chiang YH; Huang FC; Lin JJ
Bioorg Med Chem; 2008 Jul; 16(14):6976-86. PubMed ID: 18571928
[TBL] [Abstract][Full Text] [Related]
12. Aminoacyl-anthraquinone conjugates as telomerase inhibitors: synthesis, biophysical and biological evaluation.
Zagotto G; Sissi C; Lucatello L; Pivetta C; Cadamuro SA; Fox KR; Neidle S; Palumbo M
J Med Chem; 2008 Sep; 51(18):5566-74. PubMed ID: 18754611
[TBL] [Abstract][Full Text] [Related]
13. Structure-based design of benzylamino-acridine compounds as G-quadruplex DNA telomere targeting agents.
Martins C; Gunaratnam M; Stuart J; Makwana V; Greciano O; Reszka AP; Kelland LR; Neidle S
Bioorg Med Chem Lett; 2007 Apr; 17(8):2293-8. PubMed ID: 17276687
[TBL] [Abstract][Full Text] [Related]
14. Tri-, tetra- and heptacyclic perylene analogues as new potential antineoplastic agents based on DNA telomerase inhibition.
Sissi C; Lucatello L; Paul Krapcho A; Maloney DJ; Boxer MB; Camarasa MV; Pezzoni G; Menta E; Palumbo M
Bioorg Med Chem; 2007 Jan; 15(1):555-62. PubMed ID: 17035038
[TBL] [Abstract][Full Text] [Related]
15. Human telomerase inhibition and cytotoxicity of regioisomeric disubstituted amidoanthraquinones and aminoanthraquinones.
Huang HS; Chou CL; Guo CL; Yuan CL; Lu YC; Shieh FY; Lin JJ
Bioorg Med Chem; 2005 Mar; 13(5):1435-44. PubMed ID: 15698759
[TBL] [Abstract][Full Text] [Related]
16. Genotoxicity studies on DNA-interactive telomerase inhibitors with application as anti-cancer agents.
Harrington DJ; Cemeli E; Carder J; Fearnley J; Estdale S; Perry PJ; Jenkins TC; Anderson D
Teratog Carcinog Mutagen; 2003; Suppl 2():31-41. PubMed ID: 14691978
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis and biological evaluation of heterocyclic azoles derivatives containing pyrazine moiety as potential telomerase inhibitors.
Zhang YB; Wang XL; Liu W; Yang YS; Tang JF; Zhu HL
Bioorg Med Chem; 2012 Nov; 20(21):6356-65. PubMed ID: 23018096
[TBL] [Abstract][Full Text] [Related]
18. Structural investigations of acridine derivatives by CoMFA and CoMSIA reveal novel insight into their structures toward DNA G-quadruplex mediated telomerase inhibition and offer a highly predictive 3D-model for substituted acridines.
Zambre VP; Murumkar PR; Giridhar R; Yadav MR
J Chem Inf Model; 2009 May; 49(5):1298-311. PubMed ID: 19413274
[TBL] [Abstract][Full Text] [Related]
19. Trisubstituted acridines as G-quadruplex telomere targeting agents. Effects of extensions of the 3,6- and 9-side chains on quadruplex binding, telomerase activity, and cell proliferation.
Moore MJ; Schultes CM; Cuesta J; Cuenca F; Gunaratnam M; Tanious FA; Wilson WD; Neidle S
J Med Chem; 2006 Jan; 49(2):582-99. PubMed ID: 16420044
[TBL] [Abstract][Full Text] [Related]
20. A chiral wedge molecule inhibits telomerase activity.
Shinohara K; Sannohe Y; Kaieda S; Tanaka K; Osuga H; Tahara H; Xu Y; Kawase T; Bando T; Sugiyama H
J Am Chem Soc; 2010 Mar; 132(11):3778-82. PubMed ID: 20192187
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]