327 related articles for article (PubMed ID: 10421634)
1. The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity.
Lisztwan J; Imbert G; Wirbelauer C; Gstaiger M; Krek W
Genes Dev; 1999 Jul; 13(14):1822-33. PubMed ID: 10421634
[TBL] [Abstract][Full Text] [Related]
2. Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex.
Iwai K; Yamanaka K; Kamura T; Minato N; Conaway RC; Conaway JW; Klausner RD; Pause A
Proc Natl Acad Sci U S A; 1999 Oct; 96(22):12436-41. PubMed ID: 10535940
[TBL] [Abstract][Full Text] [Related]
3. The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins.
Pause A; Lee S; Worrell RA; Chen DY; Burgess WH; Linehan WM; Klausner RD
Proc Natl Acad Sci U S A; 1997 Mar; 94(6):2156-61. PubMed ID: 9122164
[TBL] [Abstract][Full Text] [Related]
4. Ubiquitination of a novel deubiquitinating enzyme requires direct binding to von Hippel-Lindau tumor suppressor protein.
Li Z; Na X; Wang D; Schoen SR; Messing EM; Wu G
J Biol Chem; 2002 Feb; 277(7):4656-62. PubMed ID: 11739384
[TBL] [Abstract][Full Text] [Related]
5. Diverse effects of mutations in exon II of the von Hippel-Lindau (VHL) tumor suppressor gene on the interaction of pVHL with the cytosolic chaperonin and pVHL-dependent ubiquitin ligase activity.
Hansen WJ; Ohh M; Moslehi J; Kondo K; Kaelin WG; Welch WJ
Mol Cell Biol; 2002 Mar; 22(6):1947-60. PubMed ID: 11865071
[TBL] [Abstract][Full Text] [Related]
6. The von Hippel-Lindau tumour suppressor protein: new perspectives.
Ohh M; Kaelin WG
Mol Med Today; 1999 Jun; 5(6):257-63. PubMed ID: 10366821
[TBL] [Abstract][Full Text] [Related]
7. The pVHL-associated SCF ubiquitin ligase complex: molecular genetic analysis of elongin B and C, Rbx1 and HIF-1alpha in renal cell carcinoma.
Clifford SC; Astuti D; Hooper L; Maxwell PH; Ratcliffe PJ; Maher ER
Oncogene; 2001 Aug; 20(36):5067-74. PubMed ID: 11526493
[TBL] [Abstract][Full Text] [Related]
8. Drosophila von Hippel-Lindau tumor suppressor complex possesses E3 ubiquitin ligase activity.
Aso T; Yamazaki K; Aigaki T; Kitajima S
Biochem Biophys Res Commun; 2000 Sep; 276(1):355-61. PubMed ID: 11006129
[TBL] [Abstract][Full Text] [Related]
9. Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease.
Zatyka M; da Silva NF; Clifford SC; Morris MR; Wiesener MS; Eckardt KU; Houlston RS; Richards FM; Latif F; Maher ER
Cancer Res; 2002 Jul; 62(13):3803-11. PubMed ID: 12097293
[TBL] [Abstract][Full Text] [Related]
10. A molecular basis for stabilization of the von Hippel-Lindau (VHL) tumor suppressor protein by components of the VHL ubiquitin ligase.
Kamura T; Brower CS; Conaway RC; Conaway JW
J Biol Chem; 2002 Aug; 277(33):30388-93. PubMed ID: 12048197
[TBL] [Abstract][Full Text] [Related]
11. Identification of a novel protein (VBP-1) binding to the von Hippel-Lindau (VHL) tumor suppressor gene product.
Tsuchiya H; Iseda T; Hino O
Cancer Res; 1996 Jul; 56(13):2881-5. PubMed ID: 8674032
[TBL] [Abstract][Full Text] [Related]
12. The von Hippel-Lindau tumor suppressor gene product promotes, but is not essential for, NEDD8 conjugation to cullin-2.
Wada H; Yeh ET; Kamitani T
J Biol Chem; 1999 Dec; 274(50):36025-9. PubMed ID: 10585493
[TBL] [Abstract][Full Text] [Related]
13. Conjugation of the ubiquitin-like protein NEDD8 to cullin-2 is linked to von Hippel-Lindau tumor suppressor function.
Liakopoulos D; Büsgen T; Brychzy A; Jentsch S; Pause A
Proc Natl Acad Sci U S A; 1999 May; 96(10):5510-5. PubMed ID: 10318914
[TBL] [Abstract][Full Text] [Related]
14. Studying interactions of four proteins in the yeast two-hybrid system: structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein.
Pause A; Peterson B; Schaffar G; Stearman R; Klausner RD
Proc Natl Acad Sci U S A; 1999 Aug; 96(17):9533-8. PubMed ID: 10449727
[TBL] [Abstract][Full Text] [Related]
15. The von Hippel-Lindau protein interacts with heteronuclear ribonucleoprotein a2 and regulates its expression.
Pioli PA; Rigby WF
J Biol Chem; 2001 Oct; 276(43):40346-52. PubMed ID: 11517223
[TBL] [Abstract][Full Text] [Related]
16. The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2.
Kamura T; Conrad MN; Yan Q; Conaway RC; Conaway JW
Genes Dev; 1999 Nov; 13(22):2928-33. PubMed ID: 10579999
[TBL] [Abstract][Full Text] [Related]
17. Identification of a deubiquitinating enzyme subfamily as substrates of the von Hippel-Lindau tumor suppressor.
Li Z; Wang D; Na X; Schoen SR; Messing EM; Wu G
Biochem Biophys Res Commun; 2002 Jun; 294(3):700-9. PubMed ID: 12056827
[TBL] [Abstract][Full Text] [Related]
18. Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL.
Hergovich A; Lisztwan J; Barry R; Ballschmieter P; Krek W
Nat Cell Biol; 2003 Jan; 5(1):64-70. PubMed ID: 12510195
[TBL] [Abstract][Full Text] [Related]
19. Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex.
Kamura T; Sato S; Iwai K; Czyzyk-Krzeska M; Conaway RC; Conaway JW
Proc Natl Acad Sci U S A; 2000 Sep; 97(19):10430-5. PubMed ID: 10973499
[TBL] [Abstract][Full Text] [Related]
20. Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.
Kamura T; Koepp DM; Conrad MN; Skowyra D; Moreland RJ; Iliopoulos O; Lane WS; Kaelin WG; Elledge SJ; Conaway RC; Harper JW; Conaway JW
Science; 1999 Apr; 284(5414):657-61. PubMed ID: 10213691
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]