155 related articles for article (PubMed ID: 10426812)
1. N-Acetyltransferase expression and DNA binding of N-hydroxyheterocyclic amines in human prostate epithelium.
Wang CY; Debiec-Rychter M; Schut HA; Morse P; Jones RF; Archer C; King CM; Haas GP
Carcinogenesis; 1999 Aug; 20(8):1591-5. PubMed ID: 10426812
[TBL] [Abstract][Full Text] [Related]
2. Effect of N-acetyltransferase 2 polymorphism on tumor target tissue DNA adduct levels in rapid and slow acetylator congenic rats administered 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine or 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline.
Metry KJ; Neale JR; Bendaly J; Smith NB; Pierce WM; Hein DW
Drug Metab Dispos; 2009 Nov; 37(11):2123-6. PubMed ID: 19666988
[TBL] [Abstract][Full Text] [Related]
3. Effects of single nucleotide polymorphisms in human N-acetyltransferase 2 on metabolic activation (O-acetylation) of heterocyclic amine carcinogens.
Hein DW; Fretland AJ; Doll MA
Int J Cancer; 2006 Sep; 119(5):1208-11. PubMed ID: 16570281
[TBL] [Abstract][Full Text] [Related]
4. Metabolic Activation of the Cooked Meat Carcinogen 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine in Human Prostate.
Bellamri M; Xiao S; Murugan P; Weight CJ; Turesky RJ
Toxicol Sci; 2018 Jun; 163(2):543-556. PubMed ID: 29596660
[TBL] [Abstract][Full Text] [Related]
5. A comprehensive approach to the profiling of the cooked meat carcinogens 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, and their metabolites in human urine.
Gu D; McNaughton L; Lemaster D; Lake BG; Gooderham NJ; Kadlubar FF; Turesky RJ
Chem Res Toxicol; 2010 Apr; 23(4):788-801. PubMed ID: 20192249
[TBL] [Abstract][Full Text] [Related]
6. Metabolism of heterocyclic aromatic amines by human hepatocytes and cytochrome P4501A2.
Turesky RJ; Guengerich FP; Guillouzo A; Langouët S
Mutat Res; 2002 Sep; 506-507():187-95. PubMed ID: 12351158
[TBL] [Abstract][Full Text] [Related]
7. Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon.
Turesky RJ; Lang NP; Butler MA; Teitel CH; Kadlubar FF
Carcinogenesis; 1991 Oct; 12(10):1839-45. PubMed ID: 1934265
[TBL] [Abstract][Full Text] [Related]
8. Interindividual variation in the metabolic activation of heterocyclic amines and their N-hydroxy derivatives in primary cultures of human mammary epithelial cells.
Stone EM; Williams JA; Grover PL; Gusterson BA; Phillips DH
Carcinogenesis; 1998 May; 19(5):873-9. PubMed ID: 9635877
[TBL] [Abstract][Full Text] [Related]
9. Cytotoxicity, DNA adduct formation and DNA repair induced by 2-hydroxyamino-3-methylimidazo[4,5-f]quinoline and 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in cultured human mammary epithelial cells.
Fan L; Schut HA; Snyderwine EG
Carcinogenesis; 1995 Apr; 16(4):775-9. PubMed ID: 7728954
[TBL] [Abstract][Full Text] [Related]
10. Protection against 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine cytotoxicity and DNA adduct formation in human prostate by glutathione S-transferase P1.
Nelson CP; Kidd LC; Sauvageot J; Isaacs WB; De Marzo AM; Groopman JD; Nelson WG; Kensler TW
Cancer Res; 2001 Jan; 61(1):103-9. PubMed ID: 11196146
[TBL] [Abstract][Full Text] [Related]
11. Excretion of food-derived heterocyclic amine carcinogens into breast milk of lactating rats and formation of DNA adducts in the newborn.
Ghoshal A; Snyderwine EG
Carcinogenesis; 1993 Nov; 14(11):2199-203. PubMed ID: 8242844
[TBL] [Abstract][Full Text] [Related]
12. Biomonitoring DNA Adducts of Cooked Meat Carcinogens in Human Prostate by Nano Liquid Chromatography-High Resolution Tandem Mass Spectrometry: Identification of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine DNA Adduct.
Xiao S; Guo J; Yun BH; Villalta PW; Krishna S; Tejpaul R; Murugan P; Weight CJ; Turesky RJ
Anal Chem; 2016 Dec; 88(24):12508-12515. PubMed ID: 28139123
[TBL] [Abstract][Full Text] [Related]
13. Urinary excretion of unmetabolized and phase II conjugates of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in humans: relationship to cytochrome P4501A2 and N-acetyltransferase activity.
Stillwell WG; Kidd LC; Wishnok JS; Tannenbaum SR; Sinha R
Cancer Res; 1997 Aug; 57(16):3457-64. PubMed ID: 9270013
[TBL] [Abstract][Full Text] [Related]
14. Metabolic processing and disposition of 2-amino-3-methylimidazo[4,5-f] quinoline (IQ), 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in nonhuman primates.
Snyderwine EG; Turesky RJ; Buonarati MH; Turteltaub KW; Adamson RH
Princess Takamatsu Symp; 1995; 23():69-77. PubMed ID: 8844797
[TBL] [Abstract][Full Text] [Related]
15. Possible mechanisms for PhIP-DNA adduct formation in the mammary gland of female Sprague-Dawley rats.
Ghoshal A; Davis CD; Schut HA; Snyderwine EG
Carcinogenesis; 1995 Nov; 16(11):2725-31. PubMed ID: 7586192
[TBL] [Abstract][Full Text] [Related]
16. N-acetyltransferase expression and metabolic activation of the food-derived heterocyclic amines in the human mammary gland.
Sadrieh N; Davis CD; Snyderwine EG
Cancer Res; 1996 Jun; 56(12):2683-7. PubMed ID: 8665493
[TBL] [Abstract][Full Text] [Related]
17. N-oxidative metabolism of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in humans: excretion of the N2-glucuronide conjugate of 2-hydroxyamino-MeIQx in urine.
Stillwell WG; Turesky RJ; Sinha R; Tannenbaum SR
Cancer Res; 1999 Oct; 59(20):5154-9. PubMed ID: 10537291
[TBL] [Abstract][Full Text] [Related]
18. Effects of human and rat glutathione S-transferases on the covalent DNA binding of the N-acetoxy derivatives of heterocyclic amine carcinogens in vitro: a possible mechanism of organ specificity in their carcinogenesis.
Lin D; Meyer DJ; Ketterer B; Lang NP; Kadlubar FF
Cancer Res; 1994 Sep; 54(18):4920-6. PubMed ID: 8069858
[TBL] [Abstract][Full Text] [Related]
19. 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine-induced DNA adducts and genotoxicity in chinese hamster ovary (CHO) cells expressing human CYP1A2 and rapid or slow acetylator N-acetyltransferase 2.
Metry KJ; Zhao S; Neale JR; Doll MA; States JC; McGregor WG; Pierce WM; Hein DW
Mol Carcinog; 2007 Jul; 46(7):553-63. PubMed ID: 17295238
[TBL] [Abstract][Full Text] [Related]
20. N-acetyltransferase-dependent activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine: formation of 2-amino-1-methyl-6-(5-hydroxy)phenylimidazo [4,5-b]pyridine, a possible biomarker for the reactive dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Frandsen H; Alexander J
Carcinogenesis; 2000 Jun; 21(6):1197-203. PubMed ID: 10837010
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
