These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 10430617)

  • 1. The Gly972-->Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cells.
    Porzio O; Federici M; Hribal ML; Lauro D; Accili D; Lauro R; Borboni P; Sesti G
    J Clin Invest; 1999 Aug; 104(3):357-64. PubMed ID: 10430617
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The common Arg972 polymorphism in insulin receptor substrate-1 causes apoptosis of human pancreatic islets.
    Federici M; Hribal ML; Ranalli M; Marselli L; Porzio O; Lauro D; Borboni P; Lauro R; Marchetti P; Melino G; Sesti G
    FASEB J; 2001 Jan; 15(1):22-24. PubMed ID: 11099486
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Gly-->Arg972 amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells.
    Hribal ML; Federici M; Porzio O; Lauro D; Borboni P; Accili D; Lauro R; Sesti G
    J Clin Endocrinol Metab; 2000 May; 85(5):2004-13. PubMed ID: 10843189
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells.
    Andreozzi F; D'Alessandris C; Federici M; Laratta E; Del Guerra S; Del Prato S; Marchetti P; Lauro R; Perticone F; Sesti G
    Endocrinology; 2004 Jun; 145(6):2845-57. PubMed ID: 15001544
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chronic hyperglycemia impairs insulin secretion by affecting insulin receptor expression, splicing, and signaling in RIN beta cell line and human islets of Langerhans.
    Hribal ML; Perego L; Lovari S; Andreozzi F; Menghini R; Perego C; Finzi G; Usellini L; Placidi C; Capella C; Guzzi V; Lauro D; Bertuzzi F; Davalli A; Pozza G; Pontiroli A; Federici M; Lauro R; Brunetti A; Folli F; Sesti G
    FASEB J; 2003 Jul; 17(10):1340-2. PubMed ID: 12738810
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Expression of variant forms of insulin receptor substrate-1 identified in patients with noninsulin-dependent diabetes mellitus.
    Imai Y; Philippe N; Sesti G; Accili D; Taylor SI
    J Clin Endocrinol Metab; 1997 Dec; 82(12):4201-7. PubMed ID: 9398740
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling. Evidence from transfection studies.
    Almind K; Inoue G; Pedersen O; Kahn CR
    J Clin Invest; 1996 Jun; 97(11):2569-75. PubMed ID: 8647950
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insulin secretory function is impaired in isolated human islets carrying the Gly(972)-->Arg IRS-1 polymorphism.
    Marchetti P; Lupi R; Federici M; Marselli L; Masini M; Boggi U; Del Guerra S; Patanè G; Piro S; Anello M; Bergamini E; Purrello F; Lauro R; Mosca F; Sesti G; Del Prato S
    Diabetes; 2002 May; 51(5):1419-24. PubMed ID: 11978638
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rosiglitazone reverses insulin secretion altered by chronic exposure to free fatty acid via IRS-2-associated phosphatidylinositol 3-kinase pathway.
    Yang L; An HX; Deng XL; Chen LL; Li ZY
    Acta Pharmacol Sin; 2003 May; 24(5):429-34. PubMed ID: 12740178
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential role of insulin receptor substrate (IRS)-1 and IRS-2 in L6 skeletal muscle cells expressing the Arg1152 --> Gln insulin receptor.
    Miele C; Caruso M; Calleja V; Auricchio R; Oriente F; Formisano P; Condorelli G; Cafieri A; Sawka-Verhelle D; Van Obberghen E; Beguinot F
    J Biol Chem; 1999 Jan; 274(5):3094-102. PubMed ID: 9915848
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel T608R missense mutation in insulin receptor substrate-1 identified in a subject with type 2 diabetes impairs metabolic insulin signaling.
    Esposito DL; Li Y; Vanni C; Mammarella S; Veschi S; Della Loggia F; Mariani-Costantini R; Battista P; Quon MJ; Cama A
    J Clin Endocrinol Metab; 2003 Apr; 88(4):1468-75. PubMed ID: 12679424
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A specific increased expression of insulin receptor substrate 2 in pancreatic beta-cell lines is involved in mediating serum-stimulated beta-cell growth.
    Schuppin GT; Pons S; Hügl S; Aiello LP; King GL; White M; Rhodes CJ
    Diabetes; 1998 Jul; 47(7):1074-85. PubMed ID: 9648831
    [TBL] [Abstract][Full Text] [Related]  

  • 13. GTK tyrosine kinase-induced alteration of IRS-protein signalling in insulin producing cells.
    Annerén C; Welsh M
    Mol Med; 2002 Nov; 8(11):705-13. PubMed ID: 12520087
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Islet transplantation restores normal levels of insulin receptor and substrate tyrosine phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle and myocardium of streptozocin-induced diabetic rats.
    Giorgino F; Logoluso F; Davalli AM; Napoli R; Laviola L; Hirshman MF; Horton ES; Weir GC; Smith RJ
    Diabetes; 1999 Apr; 48(4):801-12. PubMed ID: 10102697
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glucose-induced insulin receptor tyrosine phosphorylation in insulin-secreting beta-cells.
    Rothenberg PL; Willison LD; Simon J; Wolf BA
    Diabetes; 1995 Jul; 44(7):802-9. PubMed ID: 7540574
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Restoration of insulin secretion in pancreatic islets of protein-deficient rats by reduced expression of insulin receptor substrate (IRS)-1 and IRS-2.
    Araujo EP; Amaral ME; Filiputti E; De Souza CT; Laurito TL; Augusto VD; Saad MJ; Boschero AC; Velloso LA; Carneiro EM
    J Endocrinol; 2004 Apr; 181(1):25-38. PubMed ID: 15072564
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prolactin-signal transduction in neonatal rat pancreatic islets and interaction with the insulin-signaling pathway.
    Amaral ME; Ueno M; Carvalheira JB; Carneiro EM; Velloso LA; Saad MJ; Boschero AC
    Horm Metab Res; 2003 May; 35(5):282-9. PubMed ID: 12915997
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reciprocal feedback regulation of insulin receptor and insulin receptor substrate tyrosine phosphorylation by phosphoinositide 3-kinase in primary adipocytes.
    Hers I; Bell CJ; Poole AW; Jiang D; Denton RM; Schaefer E; Tavaré JM
    Biochem J; 2002 Dec; 368(Pt 3):875-84. PubMed ID: 12220227
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Insulin receptor substrate 1-induced inhibition of endoplasmic reticulum Ca2+ uptake in beta-cells. Autocrine regulation of intracellular ca2+ homeostasis and insulin secretion.
    Xu GG; Gao ZY; Borge PD; Wolf BA
    J Biol Chem; 1999 Jun; 274(25):18067-74. PubMed ID: 10364259
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glucose- and insulin-induced phosphorylation of the insulin receptor and its primary substrates IRS-1 and IRS-2 in rat pancreatic islets.
    Velloso LA; Carneiro EM; Crepaldi SC; Boschero AC; Saad MJ
    FEBS Lett; 1995 Dec; 377(3):353-7. PubMed ID: 8549754
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.