These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

94 related articles for article (PubMed ID: 10431804)

  • 1. Expression of a functionally active human hepatic UDP-glucuronosyltransferase (UGT1A6) lacking the N-terminal signal sequence in the endoplasmic reticulum.
    Ouzzine M; Magdalou J; Burchell B; Fournel-Gigleux S
    FEBS Lett; 1999 Jul; 454(3):187-91. PubMed ID: 10431804
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An internal signal sequence mediates the targeting and retention of the human UDP-glucuronosyltransferase 1A6 to the endoplasmic reticulum.
    Ouzzine M; Magdalou J; Burchell B; Fournel-Gigleux S
    J Biol Chem; 1999 Oct; 274(44):31401-9. PubMed ID: 10531341
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Photoaffinity labeling of the aglycon binding site of the recombinant human liver UDP-glucuronosyltransferase UGT1A6 with 7-azido-4-methylcoumarin.
    Senay C; Battaglia E; Chen G; Breton R; Fournel-Gigleux S; Magdalou J; Radominska-Pandya A
    Arch Biochem Biophys; 1999 Aug; 368(1):75-84. PubMed ID: 10415114
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The importance of cysteine 126 in the human liver UDP-glucuronosyltransferase UGT1A6.
    Senay C; Jedlitschky G; Terrier N; Burchell B; Magdalou J; Fournel-Gigleux S
    Biochim Biophys Acta; 2002 May; 1597(1):90-6. PubMed ID: 12009407
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Carrier-mediated transport of uridine diphosphoglucuronic acid across the endoplasmic reticulum membrane is a prerequisite for UDP-glucuronosyltransferase activity in rat liver.
    Bossuyt X; Blanckaert N
    Biochem J; 1997 May; 323 ( Pt 3)(Pt 3):645-8. PubMed ID: 9169596
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A membrane transporter mediates access of uridine 5'-diphosphoglucuronic acid from the cytosol into the endoplasmic reticulum of rat hepatocytes: implications for glucuronidation reactions.
    Hauser SC; Ziurys JC; Gollan JL
    Biochim Biophys Acta; 1988 Nov; 967(2):149-57. PubMed ID: 3142526
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of glucuronidation through reduction of a disulfide bond in rat UDP-glucuronosyltransferase 1A6.
    Ikushiro S; Emi Y; Iyanagi T
    Biochemistry; 2002 Oct; 41(42):12813-20. PubMed ID: 12379124
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Investigation of the Endoplasmic Reticulum Localization of UDP-Glucuronosyltransferase 2B7 with Systematic Deletion Mutants.
    Miyauchi Y; Kimura S; Kimura A; Kurohara K; Hirota Y; Fujimoto K; Mackenzie PI; Tanaka Y; Ishii Y
    Mol Pharmacol; 2019 May; 95(5):551-562. PubMed ID: 30944207
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A6 enzymes.
    Hanioka N; Takeda Y; Jinno H; Tanaka-Kagawa T; Naito S; Koeda A; Shimizu T; Nomura M; Narimatsu S
    Chem Biol Interact; 2006 Dec; 164(1-2):136-45. PubMed ID: 17027947
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evaluation of 5-hydroxytryptophol and other endogenous serotonin (5-hydroxytryptamine) analogs as substrates for UDP-glucuronosyltransferase 1A6.
    Krishnaswamy S; Hao Q; Von Moltke LL; Greenblatt DJ; Court MH
    Drug Metab Dispos; 2004 Aug; 32(8):862-9. PubMed ID: 15258112
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The carboxyl-terminal di-lysine motif is essential for catalytic activity of UDP-glucuronosyltransferase 1A9.
    Miyauchi Y; Kurohara K; Kimura A; Esaki M; Fujimoto K; Hirota Y; Takechi S; Mackenzie PI; Ishii Y; Tanaka Y
    Drug Metab Pharmacokinet; 2020 Oct; 35(5):466-474. PubMed ID: 32883578
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of the carboxyl terminal stop transfer sequence of UGT1A6 membrane protein in ER targeting and translocation of upstream lumenal domain.
    Ouzzine M; Barré L; Netter P; Magdalou J; Fournel-Gigleux S
    FEBS Lett; 2006 Apr; 580(8):1953-8. PubMed ID: 16529747
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The "albumin effect" and drug glucuronidation: bovine serum albumin and fatty acid-free human serum albumin enhance the glucuronidation of UDP-glucuronosyltransferase (UGT) 1A9 substrates but not UGT1A1 and UGT1A6 activities.
    Rowland A; Knights KM; Mackenzie PI; Miners JO
    Drug Metab Dispos; 2008 Jun; 36(6):1056-62. PubMed ID: 18362158
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Deferiprone glucuronidation by human tissues and recombinant UDP glucuronosyltransferase 1A6: an in vitro investigation of genetic and splice variants.
    Benoit-Biancamano MO; Connelly J; Villeneuve L; Caron P; Guillemette C
    Drug Metab Dispos; 2009 Feb; 37(2):322-9. PubMed ID: 18971318
    [TBL] [Abstract][Full Text] [Related]  

  • 15. UDP glucuronosyltransferase (UGT) 1A6 pharmacogenetics: I. Identification of polymorphisms in the 5'-regulatory and exon 1 regions, and association with human liver UGT1A6 gene expression and glucuronidation.
    Krishnaswamy S; Hao Q; Al-Rohaimi A; Hesse LM; von Moltke LL; Greenblatt DJ; Court MH
    J Pharmacol Exp Ther; 2005 Jun; 313(3):1331-9. PubMed ID: 15761114
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A mutation which disrupts the hydrophobic core of the signal peptide of bilirubin UDP-glucuronosyltransferase, an endoplasmic reticulum membrane protein, causes Crigler-Najjar type II.
    Seppen J; Steenken E; Lindhout D; Bosma PJ; Elferink RP
    FEBS Lett; 1996 Jul; 390(3):294-8. PubMed ID: 8706880
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular cloning and functional analysis of minipig UDP-glucuronosyltransferase 1A6.
    Miyake Y; Hirose R; Isobe T; Hanioka N
    Xenobiotica; 2016; 46(3):193-9. PubMed ID: 26134041
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Importance of histidine residues for the function of the human liver UDP-glucuronosyltransferase UGT1A6: evidence for the catalytic role of histidine 370.
    Ouzzine M; Antonio L; Burchell B; Netter P; Fournel-Gigleux S; Magdalou J
    Mol Pharmacol; 2000 Dec; 58(6):1609-15. PubMed ID: 11093802
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterizing the effects of common UDP glucuronosyltransferase (UGT) 1A6 and UGT1A1 polymorphisms on cis- and trans-resveratrol glucuronidation.
    Iwuchukwu OF; Ajetunmobi J; Ung D; Nagar S
    Drug Metab Dispos; 2009 Aug; 37(8):1726-32. PubMed ID: 19406951
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An alternative promoter contributes to tissue- and inducer-specific expression of the rat UDP-glucuronosyltransferase 1A6 gene.
    Auyeung DJ; Kessler FK; Ritter JK
    Toxicol Appl Pharmacol; 2001 Jul; 174(1):60-8. PubMed ID: 11437649
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.