BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

502 related articles for article (PubMed ID: 10433487)

  • 1. Induction of apoptosis in human mitogen-activated peripheral blood T-lymphocytes by the ether phospholipid ET-18-OCH3: involvement of the Fas receptor/ligand system.
    Cabaner C; Gajate C; Macho A; Muñoz E; Modolell M; Mollinedo F
    Br J Pharmacol; 1999 Jun; 127(4):813-25. PubMed ID: 10433487
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ET-18-OCH3 (edelfosine): a selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 death receptor.
    Mollinedo F; Gajate C; Martín-Santamaría S; Gago F
    Curr Med Chem; 2004 Dec; 11(24):3163-84. PubMed ID: 15579006
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Involvement of c-Jun NH2-terminal kinase activation and c-Jun in the induction of apoptosis by the ether phospholipid 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine.
    Gajate C; Santos-Beneit A; Modolell M; Mollinedo F
    Mol Pharmacol; 1998 Apr; 53(4):602-12. PubMed ID: 9547349
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Intracellular triggering of Fas, independently of FasL, as a new mechanism of antitumor ether lipid-induced apoptosis.
    Gajate C; Fonteriz RI; Cabaner C; Alvarez-Noves G; Alvarez-Rodriguez Y; Modolell M; Mollinedo F
    Int J Cancer; 2000 Mar; 85(5):674-82. PubMed ID: 10699948
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Involvement of mitochondria and caspase-3 in ET-18-OCH(3)-induced apoptosis of human leukemic cells.
    Gajate C; Santos-Beneit AM; Macho A; Lazaro Md; Hernandez-De Rojas A; Modolell M; Muñoz E; Mollinedo F
    Int J Cancer; 2000 Apr; 86(2):208-18. PubMed ID: 10738248
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Selective induction of apoptosis in cancer cells by the ether lipid ET-18-OCH3 (Edelfosine): molecular structure requirements, cellular uptake, and protection by Bcl-2 and Bcl-X(L).
    Mollinedo F; Fernández-Luna JL; Gajate C; Martín-Martín B; Benito A; Martínez-Dalmau R; Modolell M
    Cancer Res; 1997 Apr; 57(7):1320-8. PubMed ID: 9102220
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mitochondrial-derived ROS in edelfosine-induced apoptosis in yeasts and tumor cells.
    Zhang H; Gajate C; Yu LP; Fang YX; Mollinedo F
    Acta Pharmacol Sin; 2007 Jun; 28(6):888-94. PubMed ID: 17506948
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Intracellular triggering of Fas aggregation and recruitment of apoptotic molecules into Fas-enriched rafts in selective tumor cell apoptosis.
    Gajate C; Del Canto-Jañez E; Acuña AU; Amat-Guerri F; Geijo E; Santos-Beneit AM; Veldman RJ; Mollinedo F
    J Exp Med; 2004 Aug; 200(3):353-65. PubMed ID: 15289504
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Altered mitochondrial function and overgeneration of reactive oxygen species precede the induction of apoptosis by 1-O-octadecyl-2-methyl-rac-glycero-3-phosphocholine in p53-defective hepatocytes.
    Vrablic AS; Albright CD; Craciunescu CN; Salganik RI; Zeisel SH
    FASEB J; 2001 Aug; 15(10):1739-44. PubMed ID: 11481221
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The ether lipid 1-octadecyl-2-methyl-rac-glycero-3-phosphocholine induces expression of fos and jun proto-oncogenes and activates AP-1 transcription factor in human leukaemic cells.
    Mollinedo F; Gajate C; Modolell M
    Biochem J; 1994 Sep; 302 ( Pt 2)(Pt 2):325-9. PubMed ID: 8092982
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Involvement of raft aggregates enriched in Fas/CD95 death-inducing signaling complex in the antileukemic action of edelfosine in Jurkat cells.
    Gajate C; Gonzalez-Camacho F; Mollinedo F
    PLoS One; 2009; 4(4):e5044. PubMed ID: 19352436
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dissociation of the effects of the antitumour ether lipid ET-18-OCH3 on cytosolic calcium and on apoptosis.
    Alonso MT; Gajate C; Mollinedo F; Modolell M; Alvarez J; García-Sancho J
    Br J Pharmacol; 1997 Aug; 121(7):1364-8. PubMed ID: 9257915
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of growth factor-dependent inositol phosphate Ca2+ signaling by antitumor ether lipid analogues.
    Seewald MJ; Olsen RA; Sehgal I; Melder DC; Modest EJ; Powis G
    Cancer Res; 1990 Aug; 50(15):4458-63. PubMed ID: 2369723
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rosmarinic acid induces p56lck-dependent apoptosis in Jurkat and peripheral T cells via mitochondrial pathway independent from Fas/Fas ligand interaction.
    Hur YG; Yun Y; Won J
    J Immunol; 2004 Jan; 172(1):79-87. PubMed ID: 14688312
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of the anti-neoplastic agents edelfosine (ET-18-OCH3), ilmofosine (BM 41.440) and the hexadecylphosphocholine analogues D-20133 and D-21266 on histamine release from isolated rat mast cells.
    Grosman N
    Immunopharmacology; 1999 Nov; 44(3):211-21. PubMed ID: 10598878
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ET-18-OCH3 inhibits nuclear factor-kappa B activation by 12-O-tetradecanoylphorbol-13-acetate but not by tumor necrosis factor-alpha or interleukin 1 alpha.
    Daniel LW; Civoli F; Rogers MA; Smitherman PK; Raju PA; Roederer M
    Cancer Res; 1995 Nov; 55(21):4844-9. PubMed ID: 7585518
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selective induction of apoptosis by capsaicin in transformed cells: the role of reactive oxygen species and calcium.
    Macho A; Calzado MA; Muñoz-Blanco J; Gómez-Díaz C; Gajate C; Mollinedo F; Navas P; Muñoz E
    Cell Death Differ; 1999 Feb; 6(2):155-65. PubMed ID: 10200562
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The CB1/VR1 agonist arvanil induces apoptosis through an FADD/caspase-8-dependent pathway.
    Sancho R; de la Vega L; Appendino G; Di Marzo V; Macho A; Munoz E
    Br J Pharmacol; 2003 Nov; 140(6):1035-44. PubMed ID: 14530215
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Examination of the sensitivity of T cells to Fas ligation: induction of allospecific apoptosis.
    O'Flaherty E; Ali S; Pettit SJ; Kirby JA
    Transplantation; 1998 Oct; 66(8):1067-73. PubMed ID: 9808493
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Liposomal ET-18-OCH(3) induces cytochrome c-mediated apoptosis independently of CD95 (APO-1/Fas) signaling.
    Cuvillier O; Mayhew E; Janoff AS; Spiegel S
    Blood; 1999 Nov; 94(10):3583-92. PubMed ID: 10552970
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.