BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 10446140)

  • 1. Half of Saccharomyces cerevisiae carbamoyl phosphate synthetase produces and channels carbamoyl phosphate to the fused aspartate transcarbamoylase domain.
    Serre V; Guy H; Penverne B; Lux M; Rotgeri A; Evans D; Hervé G
    J Biol Chem; 1999 Aug; 274(34):23794-801. PubMed ID: 10446140
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Allosteric regulation and substrate channeling in multifunctional pyrimidine biosynthetic complexes: analysis of isolated domains and yeast-mammalian chimeric proteins.
    Serre V; Guy H; Liu X; Penverne B; Hervé G; Evans D
    J Mol Biol; 1998 Aug; 281(2):363-77. PubMed ID: 9698553
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression, purification, crystallization and preliminary X-ray diffraction analysis of the aspartate transcarbamoylase domain of human CAD.
    Ruiz-Ramos A; Lallous N; Grande-García A; Ramón-Maiques S
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2013 Dec; 69(Pt 12):1425-30. PubMed ID: 24316846
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Carbamyl-phosphate synthetase domain of the yeast multifunctional protein Ura2 is necessary for aspartate transcarbamylase inhibition by UTP.
    Antonelli R; Estevez L; Denis-Duphil M
    FEBS Lett; 1998 Jan; 422(2):170-4. PubMed ID: 9489999
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Substitutions in the aspartate transcarbamoylase domain of hamster CAD disrupt oligomeric structure.
    Qiu Y; Davidson JN
    Proc Natl Acad Sci U S A; 2000 Jan; 97(1):97-102. PubMed ID: 10618377
    [TBL] [Abstract][Full Text] [Related]  

  • 6. As in Saccharomyces cerevisiae, aspartate transcarbamoylase is assembled on a multifunctional protein including a dihydroorotase-like cryptic domain in Schizosaccharomyces pombe.
    Lollier M; Jaquet L; Nedeva T; Lacroute F; Potier S; Souciet JL
    Curr Genet; 1995 Jul; 28(2):138-49. PubMed ID: 8590465
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Integrated allosteric regulation in the S. cerevisiae carbamylphosphate synthetase - aspartate transcarbamylase multifunctional protein.
    Serre V; Penverne B; Souciet JL; Potier S; Guy H; Evans D; Vicart P; Hervé G
    BMC Biochem; 2004 May; 5():6. PubMed ID: 15128434
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of the regulatory domain of the mammalian multifunctional protein CAD by the construction of an Escherichia coli hamster hybrid carbamyl-phosphate synthetase.
    Liu X; Guy HI; Evans DR
    J Biol Chem; 1994 Nov; 269(44):27747-55. PubMed ID: 7525561
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Allosteric regulation of carbamoylphosphate synthetase-aspartate transcarbamylase multifunctional protein of Saccharomyces cerevisiae: selection, mapping and identification of missense mutations define three regions involved in feedback inhibition by UTP.
    Jaquet L; Serre V; Lollier M; Penverne B; Hervé G; Souciet JL; Potier S
    J Mol Biol; 1995 May; 248(3):639-52. PubMed ID: 7752230
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Trapping an activated conformation of mammalian carbamyl-phosphate synthetase.
    Guy HI; Evans DR
    J Biol Chem; 1997 Aug; 272(32):19906-12. PubMed ID: 9242656
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A 70-amino acid zinc-binding polypeptide fragment from the regulatory chain of aspartate transcarbamoylase causes marked changes in the kinetic mechanism of the catalytic trimer.
    Zhou BB; Waldrop GL; Lum L; Schachman HK
    Protein Sci; 1994 Jun; 3(6):967-74. PubMed ID: 8069226
    [TBL] [Abstract][Full Text] [Related]  

  • 12. N-(Phosphonacetyl)-L-aspartate inhibition of the enzyme complex of pyrimidine biosynthesis.
    Moore EC
    Biochem Pharmacol; 1982 Oct; 31(20):3313-6. PubMed ID: 7150357
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pyrimidine biosynthesis in Saccharomyces cerevisiae: the ura2 cluster gene, its multifunctional enzyme product, and other structural or regulatory genes involved in de novo UMP synthesis.
    Denis-Duphil M
    Biochem Cell Biol; 1989 Sep; 67(9):612-31. PubMed ID: 2679804
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genetic analysis of yeast strains lacking negative feedback control: a one-step method for positive selection and cloning of carbamoylphosphate synthetase-aspartate transcarbamoylase mutants unable to respond to UTP.
    Jaquet L; Lollier M; Souciet JL; Potier S
    Mol Gen Genet; 1993 Oct; 241(1-2):81-8. PubMed ID: 8232215
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Yeast carbamoyl-phosphate-synthetase--aspartate-transcarbamylase multidomain protein is phosphorylated in vitro by cAMP-dependent protein kinase.
    Denis-Duphil M; Lecaer JP; Hardie DG; Carrey EA
    Eur J Biochem; 1990 Oct; 193(2):581-7. PubMed ID: 1977585
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A reciprocal allosteric mechanism for efficient transfer of labile intermediates between active sites in CAD, the mammalian pyrimidine-biosynthetic multienzyme polypeptide.
    Irvine HS; Shaw SM; Paton A; Carrey EA
    Eur J Biochem; 1997 Aug; 247(3):1063-73. PubMed ID: 9288932
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Correlation between restriction map, genetic map and catalytic functions in the gene complex URA2.
    Potier S; Souciet JL; Lacroute F
    Mol Gen Genet; 1987 Sep; 209(2):283-9. PubMed ID: 2823075
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CAD, A Multienzymatic Protein at the Head of de Novo Pyrimidine Biosynthesis.
    Del Caño-Ochoa F; Moreno-Morcillo M; Ramón-Maiques S
    Subcell Biochem; 2019; 93():505-538. PubMed ID: 31939163
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Aquifex aeolicus aspartate transcarbamoylase, an enzyme specialized for the efficient utilization of unstable carbamoyl phosphate at elevated temperature.
    Purcarea C; Ahuja A; Lu T; Kovari L; Guy HI; Evans DR
    J Biol Chem; 2003 Dec; 278(52):52924-34. PubMed ID: 14534296
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of the ATP binding sites of the carbamyl phosphate synthetase domain of the Syrian hamster multifunctional protein CAD by affinity labeling with 5'-[p-(fluorosulfonyl)benzoyl]adenosine.
    Kim HS; Lee L; Evans DR
    Biochemistry; 1991 Oct; 30(42):10322-9. PubMed ID: 1681900
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.