BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 10446178)

  • 1. Revisiting catalysis by chymotrypsin family serine proteases using peptide substrates and inhibitors with unnatural main chains.
    Coombs GS; Rao MS; Olson AJ; Dawson PE; Madison EL
    J Biol Chem; 1999 Aug; 274(34):24074-9. PubMed ID: 10446178
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Noncovalent inhibition of the serine proteases, alpha-chymotrypsin and trypsin by trifluoro(organo)borates.
    Smoum R; Rubinstein A; Srebnik M
    Org Biomol Chem; 2005 Mar; 3(5):941-4. PubMed ID: 15731882
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Thermodynamic criterion for the conformation of P1 residues of substrates and of inhibitors in complexes with serine proteinases.
    Qasim MA; Lu SM; Ding J; Bateman KS; James MN; Anderson S; Song J; Markley JL; Ganz PJ; Saunders CW; Laskowski M
    Biochemistry; 1999 Jun; 38(22):7142-50. PubMed ID: 10353824
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibitor binding induces active site stabilization of the HCV NS3 protein serine protease domain.
    Barbato G; Cicero DO; Cordier F; Narjes F; Gerlach B; Sambucini S; Grzesiek S; Matassa VG; De Francesco R; Bazzo R
    EMBO J; 2000 Mar; 19(6):1195-206. PubMed ID: 10716920
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site.
    Katz BA; Elrod K; Luong C; Rice MJ; Mackman RL; Sprengeler PA; Spencer J; Hataye J; Janc J; Link J; Litvak J; Rai R; Rice K; Sideris S; Verner E; Young W
    J Mol Biol; 2001 Apr; 307(5):1451-86. PubMed ID: 11292354
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Affinity and specificity of serine endopeptidase-protein inhibitor interactions. Empirical free energy calculations based on X-ray crystallographic structures.
    Krystek S; Stouch T; Novotny J
    J Mol Biol; 1993 Dec; 234(3):661-79. PubMed ID: 8254666
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-function relationship of serine protease-protein inhibitor interaction.
    Otlewski J; Jaskólski M; Buczek O; Cierpicki T; Czapińska H; Krowarsch D; Smalas AO; Stachowiak D; Szpineta A; Dadlez M
    Acta Biochim Pol; 2001; 48(2):419-28. PubMed ID: 11732612
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-function relationships in serine protease-bovine pancreatic trypsin inhibitor interaction.
    Krowarsch D; Zakrzewska M; Smalas AO; Otlewski J
    Protein Pept Lett; 2005 Jul; 12(5):403-7. PubMed ID: 16029151
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Intramolecular orbital alignments in serine protease/protein inhibitor complexes.
    Fan YH; Grégoire CA; Haseltine J
    Bioorg Med Chem; 2004 Jun; 12(11):3097-106. PubMed ID: 15142568
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ecotin: lessons on survival in a protease-filled world.
    McGrath ME; Gillmor SA; Fletterick RJ
    Protein Sci; 1995 Feb; 4(2):141-8. PubMed ID: 7757004
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets.
    Katz BA; Sprengeler PA; Luong C; Verner E; Elrod K; Kirtley M; Janc J; Spencer JR; Breitenbucher JG; Hui H; McGee D; Allen D; Martelli A; Mackman RL
    Chem Biol; 2001 Nov; 8(11):1107-21. PubMed ID: 11731301
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Three-dimensional Structure of a Kunitz-type Inhibitor in Complex with an Elastase-like Enzyme.
    García-Fernández R; Perbandt M; Rehders D; Ziegelmüller P; Piganeau N; Hahn U; Betzel C; Chávez Mde L; Redecke L
    J Biol Chem; 2015 May; 290(22):14154-65. PubMed ID: 25878249
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Episelection: novel Ki approximately nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface.
    Katz BA; Finer-Moore J; Mortezaei R; Rich DH; Stroud RM
    Biochemistry; 1995 Jul; 34(26):8264-80. PubMed ID: 7599119
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Canonical protein inhibitors of serine proteases.
    Krowarsch D; Cierpicki T; Jelen F; Otlewski J
    Cell Mol Life Sci; 2003 Nov; 60(11):2427-44. PubMed ID: 14625687
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The serpin MNEI inhibits elastase-like and chymotrypsin-like serine proteases through efficient reactions at two active sites.
    Cooley J; Takayama TK; Shapiro SD; Schechter NM; Remold-O'Donnell E
    Biochemistry; 2001 Dec; 40(51):15762-70. PubMed ID: 11747453
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hydrophobic accessible surface areas are proportional to binding energies of serine protease-protein inhibitor complexes.
    Goto K
    Biochem Biophys Res Commun; 1995 Jan; 206(2):497-501. PubMed ID: 7826367
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Binding of amino acid side-chains to S1 cavities of serine proteinases.
    Lu W; Apostol I; Qasim MA; Warne N; Wynn R; Zhang WL; Anderson S; Chiang YW; Ogin E; Rothberg I; Ryan K; Laskowski M
    J Mol Biol; 1997 Feb; 266(2):441-61. PubMed ID: 9047374
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The serine protease inhibitor family from Ascaris suum: chemical determination of the five disulfide bridges.
    Bernard VD; Peanasky RJ
    Arch Biochem Biophys; 1993 Jun; 303(2):367-76. PubMed ID: 8512322
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Probing intermolecular backbone H-bonding in serine proteinase-protein inhibitor complexes.
    Lu W; Randal M; Kossiakoff A; Kent SB
    Chem Biol; 1999 Jul; 6(7):419-27. PubMed ID: 10381402
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Coumarin and isocoumarin as serine protease inhibitors.
    Pochet L; Frédérick R; Masereel B
    Curr Pharm Des; 2004; 10(30):3781-96. PubMed ID: 15579071
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.