182 related articles for article (PubMed ID: 10448300)
1. A possibility to overcome P-glycoprotein (PGP)-mediated multidrug resistance by antibody-targeted drugs conjugated to N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer carrier.
St'astný M; Strohalm J; Plocová D; Ulbrich K; Ríhová B
Eur J Cancer; 1999 Mar; 35(3):459-66. PubMed ID: 10448300
[TBL] [Abstract][Full Text] [Related]
2. Overcoming multidrug resistance via simultaneous delivery of cytostatic drug and P-glycoprotein inhibitor to cancer cells by HPMA copolymer conjugate.
Sivak L; Subr V; Tomala J; Rihova B; Strohalm J; Etrych T; Kovar M
Biomaterials; 2017 Jan; 115():65-80. PubMed ID: 27886555
[TBL] [Abstract][Full Text] [Related]
3. Synthesis of poly[N-(2-hydroxypropyl)methacrylamide] conjugates of inhibitors of the ABC transporter that overcome multidrug resistance in doxorubicin-resistant P388 cells in vitro.
Subr V; Sivák L; Koziolová E; Braunová A; Pechar M; Strohalm J; Kabešová M; Ríhová B; Ulbrich K; Kovář M
Biomacromolecules; 2014 Aug; 15(8):3030-43. PubMed ID: 24978588
[TBL] [Abstract][Full Text] [Related]
4. Targetable HPMA copolymer-adriamycin conjugates. Recognition, internalization, and subcellular fate.
Omelyanenko V; Kopecková P; Gentry C; Kopecek J
J Control Release; 1998 Apr; 53(1-3):25-37. PubMed ID: 9741911
[TBL] [Abstract][Full Text] [Related]
5. HPMA-hydrogels containing cytostatic drugs. Kinetics of the drug release and in vivo efficacy.
St'astný M; Plocová D; Etrych T; Kovár M; Ulbrich K; Ríhová B
J Control Release; 2002 May; 81(1-2):101-11. PubMed ID: 11992683
[TBL] [Abstract][Full Text] [Related]
6. Chronic exposure of human ovarian carcinoma cells to free or HPMA copolymer-bound mesochlorin e6 does not induce P-glycoprotein-mediated multidrug resistance.
Tijerina M; Fowers KD; Kopecková P; Kopecek J
Biomaterials; 2000 Nov; 21(21):2203-10. PubMed ID: 10985494
[TBL] [Abstract][Full Text] [Related]
7. Star structure of antibody-targeted HPMA copolymer-bound doxorubicin: a novel type of polymeric conjugate for targeted drug delivery with potent antitumor effect.
Kovár M; Strohalm J; Etrych T; Ulbrich K; Ríhová B
Bioconjug Chem; 2002; 13(2):206-15. PubMed ID: 11906257
[TBL] [Abstract][Full Text] [Related]
8. Water-soluble polymers for targeted drug delivery to human squamous carcinoma of head and neck.
Nan A; Ghandehari H; Hebert C; Siavash H; Nikitakis N; Reynolds M; Sauk JJ
J Drug Target; 2005 Apr; 13(3):189-97. PubMed ID: 16036307
[TBL] [Abstract][Full Text] [Related]
9. HPMA-hydrogels result in prolonged delivery of anticancer drugs and are a promising tool for the treatment of sensitive and multidrug resistant leukaemia.
St'astný M; Plocová D; Etrych T; Ulbrich K; Ríhová B
Eur J Cancer; 2002 Mar; 38(4):602-8. PubMed ID: 11872356
[TBL] [Abstract][Full Text] [Related]
10. Overcoming multidrug resistance in Dox-resistant neuroblastoma cell lines via treatment with HPMA copolymer conjugates containing anthracyclines and P-gp inhibitors.
Koziolová E; Janoušková O; Cuchalová L; Hvězdová Z; Hraběta J; Eckschlager T; Sivák L; Ulbrich K; Etrych T; Šubr V
J Control Release; 2016 Jul; 233():136-46. PubMed ID: 27189135
[TBL] [Abstract][Full Text] [Related]
11. HPMA copolymer bound adriamycin overcomes MDR1 gene encoded resistance in a human ovarian carcinoma cell line.
Minko T; Kopecková P; Pozharov V; Kopecek J
J Control Release; 1998 Jul; 54(2):223-33. PubMed ID: 9724909
[TBL] [Abstract][Full Text] [Related]
12. Partial circumvention of P-glycoprotein-mediated multidrug resistance by doxorubicin-14-O-hemiadipate.
Leontieva OV; Preobrazhenskaya MN; Bernacki RJ
Invest New Drugs; 2002 Feb; 20(1):35-48. PubMed ID: 12003193
[TBL] [Abstract][Full Text] [Related]
13. Polymeric drugs based on conjugates of synthetic and natural macromolecules. II. Anti-cancer activity of antibody or (Fab')(2)-targeted conjugates and combined therapy with immunomodulators.
Ríhová B; Jelínková M; Strohalm J; Subr V; Plocová D; Hovorka O; Novák M; Plundrová D; Germano Y; Ulbrich K
J Control Release; 2000 Feb; 64(1-3):241-61. PubMed ID: 10640661
[TBL] [Abstract][Full Text] [Related]
14. HPMA copolymer-anticancer drug-OV-TL16 antibody conjugates. II. Processing in epithelial ovarian carcinoma cells in vitro.
Omelyanenko V; Gentry C; Kopecková P; Kopecek J
Int J Cancer; 1998 Feb; 75(4):600-8. PubMed ID: 9466663
[TBL] [Abstract][Full Text] [Related]
15. In vitro and in vivo effect of HPMA copolymer-bound doxorubicin targeted to transferrin receptor of B-cell lymphoma 38C13.
Kovár M; Strohalm J; Ulbrich K; Ríhová B
J Drug Target; 2002 Feb; 10(1):23-30. PubMed ID: 11996083
[TBL] [Abstract][Full Text] [Related]
16. Nanotherapeutics with suitable properties for advanced anticancer therapy based on HPMA copolymer-bound ritonavir via pH-sensitive spacers.
Machová D; Koziolová E; Chytil P; Venclíková K; Etrych T; Janoušková O
Eur J Pharm Biopharm; 2018 Oct; 131():141-150. PubMed ID: 30075311
[TBL] [Abstract][Full Text] [Related]
17. HPMA copolymer-anticancer drug-OV-TL16 antibody conjugates. 3. The effect of free and polymer-bound adriamycin on the expression of some genes in the OVCAR-3 human ovarian carcinoma cell line.
Kunath K; Kopecková P; Minko T; Kopecek J
Eur J Pharm Biopharm; 2000 Jan; 49(1):11-5. PubMed ID: 10613922
[TBL] [Abstract][Full Text] [Related]
18. Design of a multivalent galactoside ligand for selective targeting of HPMA copolymer-doxorubicin conjugates to human colon cancer cells.
David A; Kopecková P; Minko T; Rubinstein A; Kopecek J
Eur J Cancer; 2004 Jan; 40(1):148-57. PubMed ID: 14687799
[TBL] [Abstract][Full Text] [Related]
19. Antiproliferative effect of a lectin- and anti-Thy-1.2 antibody-targeted HPMA copolymer-bound doxorubicin on primary and metastatic human colorectal carcinoma and on human colorectal carcinoma transfected with the mouse Thy-1.2 gene.
Ríhová B; Jelínková M; Strohalm J; St'astný M; Hovorka O; Plocová D; Kovár M; Dráberová L; Ulbrich K
Bioconjug Chem; 2000; 11(5):664-73. PubMed ID: 10995209
[TBL] [Abstract][Full Text] [Related]
20. Enhanced Reactive Oxygen Species Generation by Mitochondria Targeting of Anticancer Drug To Overcome Tumor Multidrug Resistance.
Liu Y; Zhou Z; Lin X; Xiong X; Zhou R; Zhou M; Huang Y
Biomacromolecules; 2019 Oct; 20(10):3755-3766. PubMed ID: 31465208
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
