145 related articles for article (PubMed ID: 10454507)
1. In vivo formation and localization of 1,1-dichloroethylene epoxide in murine liver: identification of its glutathione conjugate 2-S-glutathionyl acetate.
Forkert PG
J Pharmacol Exp Ther; 1999 Sep; 290(3):1299-306. PubMed ID: 10454507
[TBL] [Abstract][Full Text] [Related]
2. Cytochrome P-450-dependent bioactivation of 1,1-dichloroethylene to a reactive epoxide in human lung and liver microsomes.
Dowsley TF; Reid K; Petsikas D; Ulreich JB; Fisher RL; Forkert PG
J Pharmacol Exp Ther; 1999 May; 289(2):641-8. PubMed ID: 10215634
[TBL] [Abstract][Full Text] [Related]
3. 1,1-Dichloroethylene-induced Clara cell damage is associated with in situ formation of the reactive epoxide. Immunohistochemical detection of its glutathione conjugate.
Forkert PG
Am J Respir Cell Mol Biol; 1999 Jun; 20(6):1310-8. PubMed ID: 10340951
[TBL] [Abstract][Full Text] [Related]
4. Pulmonary bioactivation of 1,1-dichloroethylene is associated with CYP2E1 levels in A/J, CD-1, and C57BL/6 mice.
Forkert PG; Boyd SM; Ulreich JB
J Pharmacol Exp Ther; 2001 Jun; 297(3):1193-200. PubMed ID: 11356946
[TBL] [Abstract][Full Text] [Related]
5. CYP2E1-dependent bioactivation of 1,1-dichloroethylene in murine lung: formation of reactive intermediates and glutathione conjugates.
Dowsley TF; Ulreich JB; Bolton JL; Park SS; Forkert PG
Toxicol Appl Pharmacol; 1996 Jul; 139(1):42-8. PubMed ID: 8685907
[TBL] [Abstract][Full Text] [Related]
6. Diminished CYP2E1 expression and formation of 2-S-glutathionyl acetate, a glutathione conjugate derived from 1,1-dichloroethylene epoxide, in murine lung tumors.
Forkert PG; Malkinson AM; Rice P; Moussa M
Drug Metab Dispos; 1999 Jan; 27(1):68-73. PubMed ID: 9884311
[TBL] [Abstract][Full Text] [Related]
7. Protection from 1,1-dichloroethylene-induced Clara cell injury by diallyl sulfone, a derivative of garlic.
Forkert PG; Lee RP; Dowsley TF; Hong JY; Ulreich JB
J Pharmacol Exp Ther; 1996 Jun; 277(3):1665-71. PubMed ID: 8667236
[TBL] [Abstract][Full Text] [Related]
8. Differential formation of 1,1-dichloroethylene-metabolites in the lungs of adult and weanling male and female mice: correlation with severities of bronchiolar cytotoxicity.
Forkert PG; Dowsley TF; Lee RP; Hong JY; Ulreich JB
J Pharmacol Exp Ther; 1996 Dec; 279(3):1484-90. PubMed ID: 8968374
[TBL] [Abstract][Full Text] [Related]
9. Differential metabolism of 1,1-dichloroethylene in livers of A/J, CD-1, and C57BL/6 mice.
Forkert PG; Boyd SM
Drug Metab Dispos; 2001 Nov; 29(11):1396-402. PubMed ID: 11602514
[TBL] [Abstract][Full Text] [Related]
10. Inactivation of hepatic CYP2E1 by an epoxide of diallyl sulfone.
Premdas PD; Bowers RJ; Forkert PG
J Pharmacol Exp Ther; 2000 Jun; 293(3):1112-20. PubMed ID: 10869417
[TBL] [Abstract][Full Text] [Related]
11. Formation of glutathione conjugates by reactive metabolites of vinylidene chloride in microsomes and isolated hepatocytes.
Liebler DC; Meredith MJ; Guengerich FP
Cancer Res; 1985 Jan; 45(1):186-93. PubMed ID: 3965130
[TBL] [Abstract][Full Text] [Related]
12. Bioactivation of 1,1-dichloroethylene to its epoxide by CYP2E1 and CYP2F enzymes.
Simmonds AC; Reilly CA; Baldwin RM; Ghanayem BI; Lanza DL; Yost GS; Collins KS; Forkert PG
Drug Metab Dispos; 2004 Sep; 32(9):1032-9. PubMed ID: 15319346
[TBL] [Abstract][Full Text] [Related]
13. Conjugation of glutathione with the reactive metabolites of 1, 1-dichloroethylene in murine lung and liver.
Forkert PG
Microsc Res Tech; 1997 Feb; 36(4):234-42. PubMed ID: 9140924
[TBL] [Abstract][Full Text] [Related]
14. Mechanisms of 1,1-dichloroethylene-induced cytotoxicity in lung and liver.
Forkert PG
Drug Metab Rev; 2001 Feb; 33(1):49-80. PubMed ID: 11270662
[TBL] [Abstract][Full Text] [Related]
15. Immunochemical assay for recognition of 2-S-glutathionyl acetate, a glutathione conjugate derived from 1,1-dichloroethylene-epoxide.
Forkert PG; Collins KS; Dowsley TF; Ross GM
J Pharmacol Exp Ther; 1997 Jun; 281(3):1422-30. PubMed ID: 9190879
[TBL] [Abstract][Full Text] [Related]
16. Epoxide formation from diallyl sulfone is associated with CYP2E1 inactivation in murine and human lungs.
Forkert PG; Premdas PD; Bowers RJ
Am J Respir Cell Mol Biol; 2000 Nov; 23(5):687-95. PubMed ID: 11062148
[TBL] [Abstract][Full Text] [Related]
17. Metabolism of the chemoprotective agent diallyl sulfide to glutathione conjugates in rats.
Jin L; Baillie TA
Chem Res Toxicol; 1997 Mar; 10(3):318-27. PubMed ID: 9084912
[TBL] [Abstract][Full Text] [Related]
18. Reaction of glutathione with the electrophilic metabolites of 1,1-dichloroethylene.
Dowsley TF; Forkert PG; Benesch LA; Bolton JL
Chem Biol Interact; 1995 Apr; 95(3):227-44. PubMed ID: 7728894
[TBL] [Abstract][Full Text] [Related]
19. Bioactivation of 1,1-dichloroethylene by CYP2E1 and CYP2F2 in murine lung.
Simmonds AC; Ghanayem BI; Sharma A; Reilly CA; Millen B; Yost GS; Forkert PG
J Pharmacol Exp Ther; 2004 Sep; 310(3):855-64. PubMed ID: 15123768
[TBL] [Abstract][Full Text] [Related]
20. Hepatic and pulmonary microsomal metabolism of naphthalene to glutathione adducts: factors affecting the relative rates of conjugate formation.
Buckpitt AR; Bahnson LS; Franklin RB
J Pharmacol Exp Ther; 1984 Nov; 231(2):291-300. PubMed ID: 6491983
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
