BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

287 related articles for article (PubMed ID: 10462539)

  • 1. Ras mutation, irrespective of cell type and p53 status, determines a cell's destiny to undergo apoptosis by okadaic acid, an inhibitor of protein phosphatase 1 and 2A.
    Rajesh D; Schell K; Verma AK
    Mol Pharmacol; 1999 Sep; 56(3):515-25. PubMed ID: 10462539
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Zoledronic acid in combination with serine/threonine phosphatase inhibitors induces enhanced cytotoxicity and apoptosis in hormone-refractory prostate cancer cell lines by decreasing the activities of PP1 and PP2A.
    Cirak Y; Varol U; Atmaca H; Kisim A; Sezgin C; Karabulut B; Uzunoglu S; Uslu R; Karaca B
    BJU Int; 2012 Dec; 110(11 Pt C):E1147-54. PubMed ID: 22882676
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of PP2A, but not PP5, mediates p53 activation by low levels of okadaic acid in rat liver epithelial cells.
    Messner DJ; Romeo C; Boynton A; Rossie S
    J Cell Biochem; 2006 Sep; 99(1):241-55. PubMed ID: 16598789
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role for protein phosphatase 2A in the regulation of Calu-3 epithelial Na+-K+-2Cl-, type 1 co-transport function.
    Liedtke CM; Wang X; Smallwood ND
    J Biol Chem; 2005 Jul; 280(27):25491-8. PubMed ID: 15899883
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Okadaic acid-induced lens epithelial cell apoptosis requires inhibition of phosphatase-1 and is associated with induction of gene expression including p53 and bax.
    Li DW; Fass U; Huizar I; Spector A
    Eur J Biochem; 1998 Oct; 257(2):351-61. PubMed ID: 9826180
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cell cycle-independent regulation of p21Waf1/Cip1 and retinoblastoma protein during okadaic acid-induced apoptosis is coupled with induction of Bax protein in human breast carcinoma cells.
    Sheikh MS; Garcia M; Zhan Q; Liu Y; Fornace AJ
    Cell Growth Differ; 1996 Dec; 7(12):1599-607. PubMed ID: 8959327
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Apoptosis induced by protein phosphatase 2A (PP2A) inhibition in T leukemia cells is negatively regulated by PP2A-associated p38 mitogen-activated protein kinase.
    Boudreau RT; Conrad DM; Hoskin DW
    Cell Signal; 2007 Jan; 19(1):139-51. PubMed ID: 16844342
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of protein phosphatase activity induces p53-dependent apoptosis in the absence of p53 transactivation.
    Yan Y; Shay JW; Wright WE; Mumby MC
    J Biol Chem; 1997 Jun; 272(24):15220-6. PubMed ID: 9182545
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protein phosphatase 1, but not protein phosphatase 2A, dephosphorylates DNA-damaging stress-induced phospho-serine 15 of p53.
    Haneda M; Kojima E; Nishikimi A; Hasegawa T; Nakashima I; Isobe K
    FEBS Lett; 2004 Jun; 567(2-3):171-4. PubMed ID: 15178317
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential inhibition and posttranslational modification of protein phosphatase 1 and 2A in MCF7 cells treated with calyculin-A, okadaic acid, and tautomycin.
    Favre B; Turowski P; Hemmings BA
    J Biol Chem; 1997 May; 272(21):13856-63. PubMed ID: 9153244
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Abbreviated cell cycle progression induced by the serine/threonine protein phosphatase inhibitor okadaic acid at concentrations that promote neoplastic transformation.
    Messner DJ; Ao P; Jagdale AB; Boynton AL
    Carcinogenesis; 2001 Aug; 22(8):1163-72. PubMed ID: 11470744
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Caspase-3 is actively involved in okadaic acid-induced lens epithelial cell apoptosis.
    Li DW; Xiang H; Mao YW; Wang J; Fass U; Zhang XY; Xu C
    Exp Cell Res; 2001 Jun; 266(2):279-91. PubMed ID: 11399056
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Apoptosis of human neutrophils induced by protein phosphatase 1/2A inhibition is caspase-independent and serine protease-dependent.
    Park HY; Song MG; Lee JS; Kim JW; Jin JO; Park JI; Chang YC; Kwak JY
    J Cell Physiol; 2007 Aug; 212(2):450-62. PubMed ID: 17311286
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The farnesyltransferase inhibitor, FTI-2153, inhibits bipolar spindle formation during mitosis independently of transformation and Ras and p53 mutation status.
    Crespo NC; Delarue F; Ohkanda J; Carrico D; Hamilton AD; Sebti SM
    Cell Death Differ; 2002 Jul; 9(7):702-9. PubMed ID: 12058275
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Combination of zoledronic acid and serine/threonine phosphatase inhibitors induces synergistic cytotoxicity and apoptosis in human breast cancer cells via inhibition of PI3K/Akt pathway.
    Surmeli Z; Gursoy P; Erdogan AP; Bozkurt E; Atmaca H; Uzunoglu S; Sezgin C; Şanlı UA; Uslu R; Karaca B
    Tumour Biol; 2016 Mar; 37(3):3665-73. PubMed ID: 26462835
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of protein phosphatase PP1 in GH3B6, but not in GH3 cells, activates the MEK/ERK/c-fos pathway and the human prolactin promoter, involving the coactivator CPB/p300.
    Manfroid I; Martial JA; Muller M
    Mol Endocrinol; 2001 Apr; 15(4):625-37. PubMed ID: 11266513
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The protein phosphatase inhibitors okadaic acid and calyculin A induce apoptosis in human osteoblastic cells.
    Morimoto Y; Ohba T; Kobayashi S; Haneji T
    Exp Cell Res; 1997 Feb; 230(2):181-6. PubMed ID: 9024777
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of protein phosphatase 1 induces apoptosis in neonatal rat cardiac myocytes: role of adrenergic receptor stimulation.
    Singh K; Communal C; Colucci WS
    Basic Res Cardiol; 2000 Oct; 95(5):389-96. PubMed ID: 11099166
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibitors of protein phosphatases 1 and 2A differentially prevent intrinsic and extrinsic apoptosis pathways.
    Chatfield K; Eastman A
    Biochem Biophys Res Commun; 2004 Oct; 323(4):1313-20. PubMed ID: 15451440
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Protein phosphatase 2A modulates the proliferation of human multiple myeloma cells via regulation of the production of reactive oxygen intermediates and anti-apoptotic factors.
    Kang HS; Choi I
    Cell Immunol; 2001 Oct; 213(1):34-44. PubMed ID: 11747354
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.