These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 10468022)

  • 1. P-glycoprotein-dependent disposition kinetics of tacrolimus: studies in mdr1a knockout mice.
    Yokogawa K; Takahashi M; Tamai I; Konishi H; Nomura M; Moritani S; Miyamoto K; Tsuji A
    Pharm Res; 1999 Aug; 16(8):1213-8. PubMed ID: 10468022
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Apparent lack of effect of P-glycoprotein on the gastrointestinal absorption of a substrate, tacrolimus, in normal mice.
    Chiou WL; Chung SM; Wu TC
    Pharm Res; 2000 Feb; 17(2):205-8. PubMed ID: 10751036
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Homozygous disruption of the mdrla P-glycoprotein gene affects blood-nerve barrier function in mice administered with neurotoxic drugs.
    Saito T; Zhang ZJ; Ohtsubo T; Noda I; Shibamori Y; Yamamoto T; Saito H
    Acta Otolaryngol; 2001 Sep; 121(6):735-42. PubMed ID: 11678173
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lowered blood concentration of tacrolimus and its recovery with changes in expression of CYP3A and P-glycoprotein after high-dose steroid therapy.
    Shimada T; Terada A; Yokogawa K; Kaneko H; Nomura M; Kaji K; Kaneko S; Kobayashi K; Miyamoto K
    Transplantation; 2002 Nov; 74(10):1419-24. PubMed ID: 12451243
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Altered pharmacokinetics of vinblastine in Mdr1a P-glycoprotein-deficient Mice.
    van Asperen J; Schinkel AH; Beijnen JH; Nooijen WJ; Borst P; van Tellingen O
    J Natl Cancer Inst; 1996 Jul; 88(14):994-9. PubMed ID: 8667431
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Disruption of mdr1a p-glycoprotein gene results in dysfunction of blood-inner ear barrier in mice.
    Zhang ZJ; Saito T; Kimura Y; Sugimoto C; Ohtsubo T; Saito H
    Brain Res; 2000 Jan; 852(1):116-26. PubMed ID: 10661503
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vitro and in vivo investigations on fluoroquinolones; effects of the P-glycoprotein efflux transporter on brain distribution of sparfloxacin.
    de Lange EC; Marchand S; van den Berg D; van der Sandt IC; de Boer AG; Delon A; Bouquet S; Couet W
    Eur J Pharm Sci; 2000 Dec; 12(2):85-93. PubMed ID: 11102735
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CYP3A5 and CYP3A4 but not MDR1 single-nucleotide polymorphisms determine long-term tacrolimus disposition and drug-related nephrotoxicity in renal recipients.
    Kuypers DR; de Jonge H; Naesens M; Lerut E; Verbeke K; Vanrenterghem Y
    Clin Pharmacol Ther; 2007 Dec; 82(6):711-25. PubMed ID: 17495880
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Brain penetration of ivermectin and selamectin in mdr1a,b P-glycoprotein- and bcrp- deficient knockout mice.
    Geyer J; Gavrilova O; Petzinger E
    J Vet Pharmacol Ther; 2009 Feb; 32(1):87-96. PubMed ID: 19161460
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Engraftment syndrome, but not acute GVHD, younger age, CYP3A5 or MDR1 polymorphisms, increases tacrolimus clearance in pediatric hematopoietic SCT.
    Yanagisawa R; Katsuyama Y; Shigemura T; Saito S; Tanaka M; Nakazawa Y; Sakashita K; Shiohara M; Koike K
    Bone Marrow Transplant; 2011 Jan; 46(1):90-7. PubMed ID: 20383212
    [TBL] [Abstract][Full Text] [Related]  

  • 11. BBB transport and P-glycoprotein functionality using MDR1A (-/-) and wild-type mice. Total brain versus microdialysis concentration profiles of rhodamine-123.
    de Lange EC; de Bock G; Schinkel AH; de Boer AG; Breimer DD
    Pharm Res; 1998 Nov; 15(11):1657-65. PubMed ID: 9833984
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Brain accumulation of sunitinib is restricted by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and can be enhanced by oral elacridar and sunitinib coadministration.
    Tang SC; Lagas JS; Lankheet NA; Poller B; Hillebrand MJ; Rosing H; Beijnen JH; Schinkel AH
    Int J Cancer; 2012 Jan; 130(1):223-33. PubMed ID: 21351087
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tacrolimus concentrations in relation to CYP3A and ABCB1 polymorphisms among solid organ transplant recipients in Korea.
    Jun KR; Lee W; Jang MS; Chun S; Song GW; Park KT; Lee SG; Han DJ; Kang C; Cho DY; Kim JQ; Min WK
    Transplantation; 2009 Apr; 87(8):1225-31. PubMed ID: 19384171
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibitory effect of cyclosporin A on p-glycoprotein function in peripheral nerves of mice treated with doxorubicin and vinblastine.
    Saito T; Zhang ZJ; Ohtsubo T; Noda I; Tokuriki M; Shibamori Y; Yamamoto T; Saito H
    Acta Otolaryngol; 2004 Apr; 124(3):313-7. PubMed ID: 15141761
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterisation of cerivastatin as a P-glycoprotein substrate: studies in P-glycoprotein-expressing cell monolayers and mdr1a/b knock-out mice.
    Kivistö KT; Zukunft J; Hofmann U; Niemi M; Rekersbrink S; Schneider S; Luippold G; Schwab M; Eichelbaum M; Fromm MF
    Naunyn Schmiedebergs Arch Pharmacol; 2004 Aug; 370(2):124-30. PubMed ID: 15322734
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interaction of triazolam and ketoconazole in P-glycoprotein-deficient mice.
    von Moltke LL; Granda BW; Grassi JM; Perloff MD; Vishnuvardhan D; Greenblatt DJ
    Drug Metab Dispos; 2004 Aug; 32(8):800-4. PubMed ID: 15258104
    [TBL] [Abstract][Full Text] [Related]  

  • 17. P-glycoprotein limits the brain penetration of nonsedating but not sedating H1-antagonists.
    Chen C; Hanson E; Watson JW; Lee JS
    Drug Metab Dispos; 2003 Mar; 31(3):312-8. PubMed ID: 12584158
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Multidrug resistance and the role of P-glycoprotein knockout mice.
    Schinkel AH; Mol CA; Wagenaar E; van Deemter L; Smit JJ; Borst P
    Eur J Cancer; 1995; 31A(7-8):1295-8. PubMed ID: 7577039
    [TBL] [Abstract][Full Text] [Related]  

  • 19. P-glycoprotein is a major determinant of norbuprenorphine brain exposure and antinociception.
    Brown SM; Campbell SD; Crafford A; Regina KJ; Holtzman MJ; Kharasch ED
    J Pharmacol Exp Ther; 2012 Oct; 343(1):53-61. PubMed ID: 22739506
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of P-glycoprotein on the brain penetration and brain pharmacodynamic activity of the MEK inhibitor cobimetinib.
    Choo EF; Ly J; Chan J; Shahidi-Latham SK; Messick K; Plise E; Quiason CM; Yang L
    Mol Pharm; 2014 Nov; 11(11):4199-207. PubMed ID: 25243894
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.