BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 10468895)

  • 1. Modulation of O6-methylguanine-DNA methyltransferase-mediated 1-(4-amino-2-methyl-5-Pyrimidinyl)- methyl-3-(2-Chloroethyl)-3-nitrosourea resistance by antisense RNA.
    Ji SP; Zhang YP
    Cancer Detect Prev; 1999; 23(5):422-7. PubMed ID: 10468895
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Efficient protection of cells from the genotoxicity of nitrosoureas by the retrovirus-mediated transfer of human O6-methylguanine-DNA methyltransferase using bicistronic vectors with human multidrug resistance gene 1.
    Suzuki M; Sugimoto Y; Tsuruo T
    Mutat Res; 1998 Jun; 401(1-2):133-41. PubMed ID: 9639692
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sensitization of acnu killing effects on HeLa S3 cells by MGMT antisense RNA transfection.
    Ji S; You Y; Wu Y; Chen J; Yang J; Zhang Y
    Chin Med Sci J; 1998 Mar; 13(1):14-9. PubMed ID: 11717917
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Modulation of O6-methylguanine-DNA methyltransferase-mediated 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea resistance by O6-benzylguanine in vitro and in vivo.
    Chen JM; Zhang YP; Sui JL; Moschel RC; Ikenaga M
    Anticancer Res; 1993; 13(3):801-5. PubMed ID: 8317915
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Retroviral coexpression of two different types of drug resistance genes to protect normal cells from combination chemotherapy.
    Suzuki M; Sugimoto Y; Tsukahara S; Okochi E; Gottesman MM; Tsuruo T
    Clin Cancer Res; 1997 Jun; 3(6):947-54. PubMed ID: 9815770
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The effect of o6-methylguanine-DNA methyltransferase (MGMT) and mismatch repair gene (hMLH1) status on the sensitivity to alkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea(ACNU) in gallbladder carcinoma cells.
    Sato K; Kitajima Y; Koga Y; Miyazaki K
    Anticancer Res; 2005; 25(6B):4021-8. PubMed ID: 16309194
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cisplatin represses transcriptional activity from the minimal promoter of the O6-methylguanine methyltransferase gene and increases sensitivity of human gallbladder cancer cells to 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-2-chloroethyl)-3-nitrosourea.
    Sato K; Kitajima Y; Nakagawachi T; Soejima H; Miyoshi A; Koga Y; Miyazaki K
    Oncol Rep; 2005 May; 13(5):899-906. PubMed ID: 15809756
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Application of antisense ribonucleic acid complementary to O6-methylguanine-deoxyribonucleic acid methyltransferase messenger ribonucleic acid for therapy of malignant gliomas.
    Nagane M; Asai A; Shibui S; Nomura K; Kuchino Y
    Neurosurgery; 1997 Aug; 41(2):434-40; discussion 440-1. PubMed ID: 9257312
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transfer and expression of human O6-methylguanine-DNA methyltransferase cDNA confers resistance of Mer- HeLa MR cells to 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosoure a.
    Yang J; Chen JM; Zhang YP
    Carcinogenesis; 1995 Sep; 16(9):2271-4. PubMed ID: 7554090
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Direct reversal of DNA damage by mutant methyltransferase protein protects mice against dose-intensified chemotherapy and leads to in vivo selection of hematopoietic stem cells.
    Ragg S; Xu-Welliver M; Bailey J; D'Souza M; Cooper R; Chandra S; Seshadri R; Pegg AE; Williams DA
    Cancer Res; 2000 Sep; 60(18):5187-95. PubMed ID: 11016647
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Retroviral-mediated expression of the P140A, but not P140A/G156A, mutant form of O6-methylguanine DNA methyltransferase protects hematopoietic cells against O6-benzylguanine sensitization to chloroethylnitrosourea treatment.
    Maze R; Kurpad C; Pegg AE; Erickson LC; Williams DA
    J Pharmacol Exp Ther; 1999 Sep; 290(3):1467-74. PubMed ID: 10454526
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protection of hematopoietic cells from O(6)-alkylation damage by O(6)-methylguanine DNA methyltransferase gene transfer: studies with different O(6)-alkylating agents and retroviral backbones.
    Jansen M; Bardenheuer W; Sorg UR; Seeber S; Flasshove M; Moritz T
    Eur J Haematol; 2001 Jul; 67(1):2-13. PubMed ID: 11553261
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential inactivation of O6-methylguanine-DNA methyltransferase activity by O6-arylmethylguanines.
    Mineura K; Fukuchi M; Kowada M; Terashima I; Kohda K
    Int J Cancer; 1995 Sep; 63(1):148-51. PubMed ID: 7558444
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased O6-methylguanine-DNA methyltransferase activity and reduced mutability in 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2- chloroethyl)-3-nitrosourea-resistant HeLa S3 cells.
    Ishida R; Takahashi T
    Carcinogenesis; 1988 Jun; 9(6):1079-83. PubMed ID: 3163531
    [TBL] [Abstract][Full Text] [Related]  

  • 15. O6-methylguanine-DNA methyltransferase and human cancer chemotherapy.
    Zhang YP; Wang DW; Chen YN; Wu Y; Xu HY; Fan GC; Bai XB; Wang XM; Li JX; Zhu L
    Sci China B; 1991 Jun; 34(6):675-82. PubMed ID: 1888434
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Correlation between promoter hypermethylation of the O6-methylguanine-deoxyribonucleic acid methyltransferase gene and prognosis in patients with high-grade astrocytic tumors treated with surgery, radiotherapy, and 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea-based chemotherapy.
    Kamiryo T; Tada K; Shiraishi S; Shinojima N; Kochi M; Ushio Y
    Neurosurgery; 2004 Feb; 54(2):349-57; discussion 357. PubMed ID: 14744281
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression of O6-methylguanine-DNA methyltransferase and chloroethylnitrosourea resistance of human brain tumors.
    Nagane M; Asai A; Shibui S; Nomura K; Matsutani M; Kuchino Y
    Jpn J Clin Oncol; 1992 Jun; 22(3):143-9. PubMed ID: 1518162
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Relationship between expression of O6-methylguanine-DNA methyltransferase, glutathione-S-transferase pi in glioblastoma and the survival of the patients treated with nimustine hydrochloride: an immunohistochemical analysis.
    Anda T; Shabani HK; Tsunoda K; Tokunaga Y; Kaminogo M; Shibata S; Hayashi T; Iseki M
    Neurol Res; 2003 Apr; 25(3):241-8. PubMed ID: 12739231
    [TBL] [Abstract][Full Text] [Related]  

  • 19. O6-methylguanine methyltransferase activity and sensitivity of Japanese tumor cell strains to 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)- 3-nitrosourea hydrochloride.
    Tsujimura T; Zhang YP; Fujio C; Chang HR; Watatani M; Ishizaki K; Kitamura H; Ikenaga M
    Jpn J Cancer Res; 1987 Nov; 78(11):1207-15. PubMed ID: 3121556
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Drug selection of mutant methylguanine methyltransferase from different oncoretroviral backbones results in multilineage hematopoietic transgene expression in primary and secondary recipients.
    Davis BM; Reese JS; Lingas K; Gerson SL
    J Hematother Stem Cell Res; 2003 Aug; 12(4):375-87. PubMed ID: 12965075
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.