224 related articles for article (PubMed ID: 10469628)
21. Use of precision-cut tissue slices in organ culture to study metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by hamster lung, liver and kidney.
Richter E; Friesenegger S; Engl J; Tricker AR
Toxicology; 2000 Apr; 144(1-3):83-91. PubMed ID: 10781874
[TBL] [Abstract][Full Text] [Related]
22. DNA and hemoglobin alkylation by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its major metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F344 rats.
Hecht SS; Trushin N
Carcinogenesis; 1988 Sep; 9(9):1665-8. PubMed ID: 3409470
[TBL] [Abstract][Full Text] [Related]
23. Investigation of the role of lipoxygenase in bioactivation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung.
Bedard LL; Smith GB; Reid KR; Petsikas D; Massey TE
Chem Res Toxicol; 2002 Oct; 15(10):1267-73. PubMed ID: 12387624
[TBL] [Abstract][Full Text] [Related]
24. Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
Upadhyaya P; Kalscheuer S; Hochalter JB; Villalta PW; Hecht SS
Chem Res Toxicol; 2008 Jul; 21(7):1468-76. PubMed ID: 18570389
[TBL] [Abstract][Full Text] [Related]
25. Extensive metabolic activation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in smokers.
Stepanov I; Upadhyaya P; Carmella SG; Feuer R; Jensen J; Hatsukami DK; Hecht SS
Cancer Epidemiol Biomarkers Prev; 2008 Jul; 17(7):1764-73. PubMed ID: 18628430
[TBL] [Abstract][Full Text] [Related]
26. Biliary excretion of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in the rat.
Schulze J; Richter E; Binder U; Zwickenpflug W
Carcinogenesis; 1992 Nov; 13(11):1961-5. PubMed ID: 1423863
[TBL] [Abstract][Full Text] [Related]
27. Inhibitory effects of nonsteroidal anti-inflammatory drugs (NSAIDs) on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in mouse lung explants.
Bouchard L; Castonguay A
Drug Metab Dispos; 1993; 21(2):293-8. PubMed ID: 8097699
[TBL] [Abstract][Full Text] [Related]
28. Tumorigenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol enantiomers and metabolites in the A/J mouse.
Upadhyaya P; Kenney PM; Hochalter JB; Wang M; Hecht SS
Carcinogenesis; 1999 Aug; 20(8):1577-82. PubMed ID: 10426810
[TBL] [Abstract][Full Text] [Related]
29. Human cervical tissue metabolizes the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, via alpha-hydroxylation and carbonyl reduction pathways.
Prokopczyk B; Trushin N; Leszczynska J; Waggoner SE; El-Bayoumy K
Carcinogenesis; 2001 Jan; 22(1):107-14. PubMed ID: 11159748
[TBL] [Abstract][Full Text] [Related]
30. Stereoselective metabolism of nicotine and tobacco-specific N-nitrosamines to 4-hydroxy-4-(3-pyridyl)butanoic acid in rats.
Trushin N; Hecht SS
Chem Res Toxicol; 1999 Feb; 12(2):164-71. PubMed ID: 10027794
[TBL] [Abstract][Full Text] [Related]
31. Metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in the patas monkey: pharmacokinetics and characterization of glucuronide metabolites.
Hecht SS; Trushin N; Reid-Quinn CA; Burak ES; Jones AB; Southers JL; Gombar CT; Carmella SG; Anderson LM; Rice JM
Carcinogenesis; 1993 Feb; 14(2):229-36. PubMed ID: 8435864
[TBL] [Abstract][Full Text] [Related]
32. The effect of a 2-h exposure to cigarette smoke on the metabolic activation of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mice.
Brown BG; Richter E; Tricker AR; Ayres PH; Doolittle DJ
Chem Biol Interact; 2001 Nov; 138(2):125-35. PubMed ID: 11672696
[TBL] [Abstract][Full Text] [Related]
33. Metabolism and DNA single strand breaks induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its analogues in primary culture of rat hepatocytes.
Liu LL; Alaoui-Jamali MA; el Alami N; Castonguay A
Cancer Res; 1990 Mar; 50(6):1810-6. PubMed ID: 2306734
[TBL] [Abstract][Full Text] [Related]
34. Metabolism of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in primary cultures of rat alveolar type II cells.
Schrader E; Hirsch-Ernst KI; Scholz E; Kahl GF; Foth H
Drug Metab Dispos; 2000 Feb; 28(2):180-5. PubMed ID: 10640516
[TBL] [Abstract][Full Text] [Related]
35. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by inducible and constitutive cytochrome P450 enzymes in rats.
Guo Z; Smith TJ; Thomas PE; Yang CS
Arch Biochem Biophys; 1992 Oct; 298(1):279-86. PubMed ID: 1524438
[TBL] [Abstract][Full Text] [Related]
36. Metabolic activation of the tobacco carcinogen 4-(methylnitrosamino)-(3-pyridyl)-1-butanone by cytochrome P450 2A13 in human fetal nasal microsomes.
Wong HL; Zhang X; Zhang QY; Gu J; Ding X; Hecht SS; Murphy SE
Chem Res Toxicol; 2005 Jun; 18(6):913-8. PubMed ID: 15962925
[TBL] [Abstract][Full Text] [Related]
37. Effects of phenobarbital and 3-methylcholanthrene induction on the formation of three glucuronide metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, NNK.
Murphy SE; Nunes MG; Hatala MA
Chem Biol Interact; 1997 Mar; 103(3):153-66. PubMed ID: 9134006
[TBL] [Abstract][Full Text] [Related]
38. Activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung microsomes by cytochromes P450, lipoxygenase, and hydroperoxides.
Smith TJ; Stoner GD; Yang CS
Cancer Res; 1995 Dec; 55(23):5566-73. PubMed ID: 7585636
[TBL] [Abstract][Full Text] [Related]
39. Kinetics and enzyme involvement in the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in microsomes of rat lung and nasal mucosa.
Smith TJ; Guo Z; Hong JY; Ning SM; Thomas PE; Yang CS
Carcinogenesis; 1992 Aug; 13(8):1409-14. PubMed ID: 1499091
[TBL] [Abstract][Full Text] [Related]
40. Effect of nicotine or cotinine on metabolism of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in isolated rat lung and liver.
Schulze J; Schrader E; Foth H; Kahl GF; Richter E
Naunyn Schmiedebergs Arch Pharmacol; 1998 Mar; 357(3):344-50. PubMed ID: 9550308
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
