367 related articles for article (PubMed ID: 10470088)
1. The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis.
Lamlum H; Ilyas M; Rowan A; Clark S; Johnson V; Bell J; Frayling I; Efstathiou J; Pack K; Payne S; Roylance R; Gorman P; Sheer D; Neale K; Phillips R; Talbot I; Bodmer W; Tomlinson I
Nat Med; 1999 Sep; 5(9):1071-5. PubMed ID: 10470088
[TBL] [Abstract][Full Text] [Related]
2. Refining the relation between 'first hits' and 'second hits' at the APC locus: the 'loose fit' model and evidence for differences in somatic mutation spectra among patients.
Crabtree M; Sieber OM; Lipton L; Hodgson SV; Lamlum H; Thomas HJ; Neale K; Phillips RK; Heinimann K; Tomlinson IP
Oncogene; 2003 Jul; 22(27):4257-65. PubMed ID: 12833148
[TBL] [Abstract][Full Text] [Related]
3. Mutation cluster region, association between germline and somatic mutations and genotype-phenotype correlation in upper gastrointestinal familial adenomatous polyposis.
Groves C; Lamlum H; Crabtree M; Williamson J; Taylor C; Bass S; Cuthbert-Heavens D; Hodgson S; Phillips R; Tomlinson I
Am J Pathol; 2002 Jun; 160(6):2055-61. PubMed ID: 12057910
[TBL] [Abstract][Full Text] [Related]
4. Inactivation of germline mutant APC alleles by attenuated somatic mutations: a molecular genetic mechanism for attenuated familial adenomatous polyposis.
Su LK; Barnes CJ; Yao W; Qi Y; Lynch PM; Steinbach G
Am J Hum Genet; 2000 Sep; 67(3):582-90. PubMed ID: 10924409
[TBL] [Abstract][Full Text] [Related]
5. The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade.
Albuquerque C; Breukel C; van der Luijt R; Fidalgo P; Lage P; Slors FJ; Leitão CN; Fodde R; Smits R
Hum Mol Genet; 2002 Jun; 11(13):1549-60. PubMed ID: 12045208
[TBL] [Abstract][Full Text] [Related]
6. Desmoid Tumors in Familial Adenomatous Polyposis.
DE Marchis ML; Tonelli F; Quaresmini D; Lovero D; Della-Morte D; Silvestris F; Guadagni F; Palmirotta R
Anticancer Res; 2017 Jul; 37(7):3357-3366. PubMed ID: 28668823
[TBL] [Abstract][Full Text] [Related]
7. Mutation analysis of the adenomatous polyposis coli (APC) gene in northwest Spanish patients with familial adenomatous polyposis (FAP) and sporadic colorectal cancer.
Ruiz-Ponte C; Vega A; Carracedo A; Barros F
Hum Mutat; 2001 Oct; 18(4):355. PubMed ID: 11668620
[TBL] [Abstract][Full Text] [Related]
8. Analysis of somatic APC mutations in rare extracolonic tumors of patients with familial adenomatous polyposis coli.
Bläker H; Sutter C; Kadmon M; Otto HF; Von Knebel-Doeberitz M; Gebert J; Helmke BM
Genes Chromosomes Cancer; 2004 Oct; 41(2):93-8. PubMed ID: 15287021
[TBL] [Abstract][Full Text] [Related]
9. APC gene mutations and colorectal adenomatosis in familial adenomatous polyposis.
Ficari F; Cama A; Valanzano R; Curia MC; Palmirotta R; Aceto G; Esposito DL; Crognale S; Lombardi A; Messerini L; Mariani-Costantini R; Tonelli F; Battista P
Br J Cancer; 2000 Jan; 82(2):348-53. PubMed ID: 10646887
[TBL] [Abstract][Full Text] [Related]
10. APC mutations in FAP-associated desmoid tumours are non-random but not 'just right'.
Latchford A; Volikos E; Johnson V; Rogers P; Suraweera N; Tomlinson I; Phillips R; Silver A
Hum Mol Genet; 2007 Jan; 16(1):78-82. PubMed ID: 17135276
[TBL] [Abstract][Full Text] [Related]
11. Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors.
Miyaki M; Konishi M; Kikuchi-Yanoshita R; Enomoto M; Igari T; Tanaka K; Muraoka M; Takahashi H; Amada Y; Fukayama M
Cancer Res; 1994 Jun; 54(11):3011-20. PubMed ID: 8187091
[TBL] [Abstract][Full Text] [Related]
12. Can APC mutation analysis contribute to therapeutic decisions in familial adenomatous polyposis? Experience from 680 FAP families.
Friedl W; Caspari R; Sengteller M; Uhlhaas S; Lamberti C; Jungck M; Kadmon M; Wolf M; Fahnenstich J; Gebert J; Möslein G; Mangold E; Propping P
Gut; 2001 Apr; 48(4):515-21. PubMed ID: 11247896
[TBL] [Abstract][Full Text] [Related]
13. APC haploinsufficiency, but not CTNNB1 or CDH1 gene mutations, accounts for a fraction of familial adenomatous polyposis patients without APC truncating mutations.
Venesio T; Balsamo A; Rondo-Spaudo M; Varesco L; Risio M; Ranzani GN
Lab Invest; 2003 Dec; 83(12):1859-66. PubMed ID: 14691304
[TBL] [Abstract][Full Text] [Related]
14. Germline and somatic mutations in exon 15 of the APC gene and K-ras mutations in duodenal adenomas in patients with familial adenomatous polyposis.
Norheim Andersen S; Løvig T; Fausa O; Rognum TO
Scand J Gastroenterol; 1999 Jun; 34(6):611-7. PubMed ID: 10440612
[TBL] [Abstract][Full Text] [Related]
15. A new germline stop codon mutation in exon 15 of the APC gene predisposing to familial adenomatous polyposis.
Schirosi L; Pellegrino M; Tarantino P; Mauro S; Tinelli A; Greco M
Int J Biol Markers; 2013 Dec; 28(4):e405-8. PubMed ID: 23873622
[TBL] [Abstract][Full Text] [Related]
16. Coexistence of somatic and germ-line mutations of APC gene in desmoid tumors from patients with familial adenomatous polyposis.
Miyaki M; Konishi M; Kikuchi-Yanoshita R; Enomoto M; Tanaka K; Takahashi H; Muraoka M; Mori T; Konishi F; Iwama T
Cancer Res; 1993 Nov; 53(21):5079-82. PubMed ID: 8221638
[TBL] [Abstract][Full Text] [Related]
17. Gastric polyposis and desmoid tumours as a new familial adenomatous polyposis clinical variant associated with
Disciglio V; Fasano C; Cariola F; Forte G; Grossi V; Sanese P; Lepore Signorile M; Resta N; Lotesoriere C; Stella A; Lolli I; Simone C
J Med Genet; 2020 May; 57(5):356-360. PubMed ID: 31591141
[TBL] [Abstract][Full Text] [Related]
18. Genetic testing for germline mutations of the APC gene in patients with apparently sporadic desmoid tumors but a family history of colorectal carcinoma.
Brueckl WM; Ballhausen WG; Förtsch T; Günther K; Fiedler W; Gentner B; Croner R; Boxberger F; Kirchner T; Hahn EG; Hohenberger W; Wein A
Dis Colon Rectum; 2005 Jun; 48(6):1275-81. PubMed ID: 15793634
[TBL] [Abstract][Full Text] [Related]
19. Germline APC mutation on the beta-catenin binding site is associated with a decreased apoptotic level in colorectal adenomas.
Venesio T; Balsamo A; Scordamaglia A; Bertolaso M; Arrigoni A; Sprujevnik T; Rossini FP; Risio M
Mod Pathol; 2003 Jan; 16(1):57-65. PubMed ID: 12527714
[TBL] [Abstract][Full Text] [Related]
20. Thyroid Carcinomas That Occur in Familial Adenomatous Polyposis Patients Recurrently Harbor Somatic Variants in
Nieminen TT; Walker CJ; Olkinuora A; Genutis LK; O'Malley M; Wakely PE; LaGuardia L; Koskenvuo L; Arola J; Lepistö AH; Brock P; Yilmaz AS; Eisfeld AK; Church JM; Peltomäki P; de la Chapelle A
Thyroid; 2020 Mar; 30(3):380-388. PubMed ID: 32024448
[No Abstract] [Full Text] [Related]
[Next] [New Search]
