These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Inhibition of xenobiotic-induced genotoxicity in cultured precision-cut human and rat liver slices. Lake BG; Beamand JA; Tredger JM; Barton PT; Renwick AB; Price RJ Mutat Res; 1999 Mar; 440(1):91-100. PubMed ID: 10095132 [TBL] [Abstract][Full Text] [Related]
4. Chemoprevention of aflatoxin B1-induced carcinogenesis by indole-3-carbinol in rat liver--predicting the outcome using early biomarkers. Manson MM; Hudson EA; Ball HW; Barrett MC; Clark HL; Judah DJ; Verschoyle RD; Neal GE Carcinogenesis; 1998 Oct; 19(10):1829-36. PubMed ID: 9806166 [TBL] [Abstract][Full Text] [Related]
5. Indole-3-carbinol and beta-naphthoflavone induction of aflatoxin B1 metabolism and cytochromes P-450 associated with bioactivation and detoxication of aflatoxin B1 in the rat. Stresser DM; Bailey GS; Williams DE Drug Metab Dispos; 1994; 22(3):383-91. PubMed ID: 8070314 [TBL] [Abstract][Full Text] [Related]
6. Induction of hepatic CYP1A by indole-3-carbinol in protection against aflatoxin B1 hepatocarcinogenesis in rainbow trout. Takahashi N; Stresser DM; Williams DE; Bailey GS Food Chem Toxicol; 1995 Oct; 33(10):841-50. PubMed ID: 7590528 [TBL] [Abstract][Full Text] [Related]
7. Differences in the hepatic P450-dependent metabolism of estrogen and tamoxifen in response to treatment of rats with 3,3'-diindolylmethane and its parent compound indole-3-carbinol. Parkin DR; Malejka-Giganti D Cancer Detect Prev; 2004; 28(1):72-9. PubMed ID: 15041081 [TBL] [Abstract][Full Text] [Related]
8. Oltipraz-mediated changes in aflatoxin B(1) biotransformation in rat liver: implications for human chemointervention. Buetler TM; Bammler TK; Hayes JD; Eaton DL Cancer Res; 1996 May; 56(10):2306-13. PubMed ID: 8625305 [TBL] [Abstract][Full Text] [Related]
9. Organ-selective induction of cytochrome P-450-dependent activities by indole-3-carbinol-derived products: influence on covalent binding of benzo[a]pyrene to hepatic and pulmonary DNA in the rat. Park JY; Bjeldanes LF Chem Biol Interact; 1992 Aug; 83(3):235-47. PubMed ID: 1516151 [TBL] [Abstract][Full Text] [Related]
10. Use of precision-cut rat liver slices for studies of xenobiotic metabolism and toxicity: comparison of the Krumdieck and Brendel tissue slicers. Price RJ; Ball SE; Renwick AB; Barton PT; Beamand JA; Lake BG Xenobiotica; 1998 Apr; 28(4):361-71. PubMed ID: 9604300 [TBL] [Abstract][Full Text] [Related]
11. Indole-3-carbinol induces a rat liver glutathione transferase subunit (Yc2) with high activity toward aflatoxin B1 exo-epoxide. Association with reduced levels of hepatic aflatoxin-DNA adducts in vivo. Stresser DM; Williams DE; McLellan LI; Harris TM; Bailey GS Drug Metab Dispos; 1994; 22(3):392-9. PubMed ID: 8070315 [TBL] [Abstract][Full Text] [Related]
12. Concurrent flavin-containing monooxygenase down-regulation and cytochrome P-450 induction by dietary indoles in rat: implications for drug-drug interaction. Katchamart S; Stresser DM; Dehal SS; Kupfer D; Williams DE Drug Metab Dispos; 2000 Aug; 28(8):930-6. PubMed ID: 10901703 [TBL] [Abstract][Full Text] [Related]
14. Broccoli-derived phytochemicals indole-3-carbinol and 3,3'-diindolylmethane exerts concentration-dependent pleiotropic effects on prostate cancer cells: comparison with other cancer preventive phytochemicals. Wang TT; Schoene NW; Milner JA; Kim YS Mol Carcinog; 2012 Mar; 51(3):244-56. PubMed ID: 21520295 [TBL] [Abstract][Full Text] [Related]
15. Modulations of P450 mRNA in liver and mammary gland and P450 activities and metabolism of estrogen in liver by treatment of rats with indole-3-carbinol. Horn TL; Reichert MA; Bliss RL; Malejka-Giganti D Biochem Pharmacol; 2002 Aug; 64(3):393-404. PubMed ID: 12147290 [TBL] [Abstract][Full Text] [Related]
16. Dietary indole-3-carbinol inhibits FMO activity and the expression of flavin-containing monooxygenase form 1 in rat liver and intestine. Larsen-Su S; Williams DE Drug Metab Dispos; 1996 Sep; 24(9):927-31. PubMed ID: 8886600 [TBL] [Abstract][Full Text] [Related]
17. Inhibitory effects of a dietary phytochemical 3,3'-diindolylmethane on the phenobarbital-induced hepatic CYP mRNA expression and CYP-catalyzed reactions in female rats. Parkin DR; Lu Y; Bliss RL; Malejka-Giganti D Food Chem Toxicol; 2008 Jul; 46(7):2451-8. PubMed ID: 18486294 [TBL] [Abstract][Full Text] [Related]
18. Regulation of hepatic cytochrome P4501A by indole-3-carbinol: transient induction with continuous feeding in rainbow trout. Takahashi N; Dashwood RH; Bjeldanes LF; Bailey GS; Williams DE Food Chem Toxicol; 1995 Feb; 33(2):111-20. PubMed ID: 7867998 [TBL] [Abstract][Full Text] [Related]
19. Effect of indole-3-carbinol on ethanol-induced liver injury and acetaldehyde-stimulated hepatic stellate cells activation using precision-cut rat liver slices. Guo Y; Wu XQ; Zhang C; Liao ZX; Wu Y; Xia ZY; Wang H Clin Exp Pharmacol Physiol; 2010 Dec; 37(12):1107-13. PubMed ID: 20880187 [TBL] [Abstract][Full Text] [Related]