59 related articles for article (PubMed ID: 10479298)
1. Pyrrolidine-3-carboxylic acids as endothelin antagonists. 4. Side chain conformational restriction leads to ET(B) selectivity.
von Geldern TW; Tasker AS; Sorensen BK; Winn M; Szczepankiewicz BG; Dixon DB; Chiou WJ; Wang L; Wessale JL; Adler A; Marsh KC; Nguyen B; Opgenorth TJ
J Med Chem; 1999 Sep; 42(18):3668-78. PubMed ID: 10479298
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis, and activity of a series of pyrrolidine-3-carboxylic acid-based, highly specific, orally active ET(B) antagonists containing a diphenylmethylamine acetamide side chain.
Liu G; Kozmina NS; Winn M; von Geldern TW; Chiou WJ; Dixon DB; Nguyen B; Marsh KC; Opgenorth TJ
J Med Chem; 1999 Sep; 42(18):3679-89. PubMed ID: 10479299
[TBL] [Abstract][Full Text] [Related]
3. Pyrrolidine-3-carboxylic acids as endothelin antagonists. 2. Sulfonamide-based ETA/ETB mixed antagonists.
Jae HS; Winn M; Dixon DB; Marsh KC; Nguyen B; Opgenorth TJ; von Geldern TW
J Med Chem; 1997 Sep; 40(20):3217-27. PubMed ID: 9379441
[TBL] [Abstract][Full Text] [Related]
4. Pharmacology of endothelin receptor antagonists ABT-627, ABT-546, A-182086 and A-192621: ex vivo and in vivo studies.
Wessale JL; Adler AL; Novosad EI; Calzadilla SV; Dayton BD; Marsh KC; Winn M; Jae HS; von Geldern TW; Opgenorth TJ; Wu-Wong JR
Clin Sci (Lond); 2002 Aug; 103 Suppl 48():112S-117S. PubMed ID: 12193067
[TBL] [Abstract][Full Text] [Related]
5. Pharmacology of endothelin receptor antagonists ABT-627, ABT-546, A-182086 and A-192621: in vitro studies.
Wu-Wong JR; Dixon DB; Chiou WJ; Sorensen BK; Liu G; Jae HS; Tasker A; von Geldern TW; Winn M; Opgenorth TJ
Clin Sci (Lond); 2002 Aug; 103 Suppl 48():107S-111S. PubMed ID: 12193066
[TBL] [Abstract][Full Text] [Related]
6. Effects of endothelin receptors ET(A) and ET(B) blockade on renal haemodynamics in normal rats and in rats with experimental congestive heart failure.
Abassi Z; Francis B; Wessale J; Ovcharenko E; Winaver J; Hoffman A
Clin Sci (Lond); 2002 Aug; 103 Suppl 48():245S-248S. PubMed ID: 12193096
[TBL] [Abstract][Full Text] [Related]
7. 2,4-Diarylpyrrolidine-3-carboxylic acids--potent ETA selective endothelin receptor antagonists. 1. Discovery of A-127722.
Winn M; von Geldern TW; Opgenorth TJ; Jae HS; Tasker AS; Boyd SA; Kester JA; Mantei RA; Bal R; Sorensen BK; Wu-Wong JR; Chiou WJ; Dixon DB; Novosad EI; Hernandez L; Marsh KC
J Med Chem; 1996 Mar; 39(5):1039-48. PubMed ID: 8676339
[TBL] [Abstract][Full Text] [Related]
8. Differential effects of endothelin A and B receptor antagonism on fetal growth in normal and nitric oxide-deficient rats.
Thaete LG; Neerhof MG; Silver RK
J Soc Gynecol Investig; 2001; 8(1):18-23. PubMed ID: 11223352
[TBL] [Abstract][Full Text] [Related]
9. Biphenylsulfonamide endothelin receptor antagonists. 4. Discovery of N-[[2'-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]- 2-yl]methyl]-N,3,3-trimethylbutanamide (BMS-207940), a highly potent and orally active ET(A) selective antagonist.
Murugesan N; Gu Z; Spergel S; Young M; Chen P; Mathur A; Leith L; Hermsmeier M; Liu EC; Zhang R; Bird E; Waldron T; Marino A; Koplowitz B; Humphreys WG; Chong S; Morrison RA; Webb ML; Moreland S; Trippodo N; Barrish JC
J Med Chem; 2003 Jan; 46(1):125-37. PubMed ID: 12502366
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of endothelin ETB receptor system aggravates neointimal hyperplasia after balloon injury of rat carotid artery.
Kitada K; Yui N; Matsumoto C; Mori T; Ohkita M; Matsumura Y
J Pharmacol Exp Ther; 2009 Dec; 331(3):998-1004. PubMed ID: 19737855
[TBL] [Abstract][Full Text] [Related]
11. Pyrrolidine-3-carboxylic acids as endothelin antagonists. 3. Discovery of a potent, 2-nonaryl, highly selective ETA antagonist (A-216546).
Liu G; Henry KJ; Szczepankiewicz BG; Winn M; Kozmina NS; Boyd SA; Wasicak J; von Geldern TW; Wu-Wong JR; Chiou WJ; Dixon DB; Nguyen B; Marsh KC; Opgenorth TJ
J Med Chem; 1998 Aug; 41(17):3261-75. PubMed ID: 9703472
[TBL] [Abstract][Full Text] [Related]
12. Influence of endothelin receptor antagonists on myocardial protein kinase C isoforms in uraemic cardiomyopathy.
Wolf SC; Amend T; Risler T; Amann K; Brehm BR
Clin Sci (Lond); 2002 Aug; 103 Suppl 48():276S-279S. PubMed ID: 12193103
[TBL] [Abstract][Full Text] [Related]
13. Effects of a selective endothelin A receptor antagonist, ABT-627, in healthy normotensive anaesthetized rats developing acute pulmonary air embolism.
Ayach B; Tsang J; Jeng AY; Blouin A; Gosselin M; Wang FH; Wu-Wong JR; Wessale J; Opgenorth TJ; Battistini B
Clin Sci (Lond); 2002 Aug; 103 Suppl 48():371S-375S. PubMed ID: 12193125
[TBL] [Abstract][Full Text] [Related]
14. Late-onset endothelin receptor blockade in hypertensive heterozygous REN-2 transgenic rats.
Vernerová Z; Kramer HJ; Bäcker A; Cervenka L; Opocenský M; Husková Z; Vanourková Z; Eis V; Chábová VC; Tesar V; Malý J; Vanecková I
Vascul Pharmacol; 2008; 48(4-6):165-73. PubMed ID: 18372220
[TBL] [Abstract][Full Text] [Related]
15. Endothelin-1-induced pulmonary vasoreactivity is regulated by ET(A) and ET(B) receptor interactions.
Sauvageau S; Thorin E; Caron A; Dupuis J
J Vasc Res; 2007; 44(5):375-81. PubMed ID: 17495482
[TBL] [Abstract][Full Text] [Related]
16. The role of endothelin-1 and the endothelin B receptor in the pathogenesis of hepatopulmonary syndrome in the rat.
Ling Y; Zhang J; Luo B; Song D; Liu L; Tang L; Stockard CR; Grizzle WE; Ku DD; Fallon MB
Hepatology; 2004 Jun; 39(6):1593-602. PubMed ID: 15185300
[TBL] [Abstract][Full Text] [Related]
17. Low NaCl intake elevates renal medullary endothelin-1 and endothelin A (ETA) receptor mRNA but not the sensitivity of renal Na+ excretion to ETA receptor blockade in rats.
Klinger F; Grimm R; Steinbach A; Tanneberger M; Kunert-Keil C; Rettig R; Grisk O
Acta Physiol (Oxf); 2008 Mar; 192(3):429-42. PubMed ID: 17892519
[TBL] [Abstract][Full Text] [Related]
18. Discovery and synthesis of (S)-3-[2-(3,4-dimethoxyphenyl)ethoxy]-2- (4,6-dimethylpyrimidin-2-yloxy)-3,3-diphenylpropionic acid (LU 302872), a novel orally active mixed ET(A)/ET(B) receptor antagonist.
Amberg W; Hergenröder S; Hillen H; Jansen R; Kettschau G; Kling A; Klinge D; Raschack M; Riechers H; Unger L
J Med Chem; 1999 Aug; 42(16):3026-32. PubMed ID: 10447946
[TBL] [Abstract][Full Text] [Related]
19. Potent and selective non-benzodioxole-containing endothelin-A receptor antagonists.
Tasker AS; Sorensen BK; Jae HS; Winn M; von Geldern TW; Dixon DB; Chiou WJ; Dayton BD; Calzadila S; Hernandez L; Marsh KC; WuWong JR; Opgenorth TJ
J Med Chem; 1997 Jan; 40(3):322-30. PubMed ID: 9022798
[TBL] [Abstract][Full Text] [Related]
20. Structure-activity relationships of N2-aryl-3-(isoxazolylsulfamoyl)-2-thiophenecarboxamides as selective endothelin receptor-A antagonists.
Wu C; Chan MF; Stavros F; Raju B; Okun I; Castillo RS
J Med Chem; 1997 May; 40(11):1682-9. PubMed ID: 9171877
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
