272 related articles for article (PubMed ID: 10479355)
1. A novel prodrug approach for tertiary amines. 2. Physicochemical and in vitro enzymatic evaluation of selected N-phosphonooxymethyl prodrugs.
Krise JP; Narisawa S; Stella VJ
J Pharm Sci; 1999 Sep; 88(9):922-7. PubMed ID: 10479355
[TBL] [Abstract][Full Text] [Related]
2. A novel prodrug approach for tertiary amines. 3. In vivo evaluation of two N-phosphonooxymethyl prodrugs in rats and dogs.
Krise JP; Charman WN; Charman SA; Stella VJ
J Pharm Sci; 1999 Sep; 88(9):928-32. PubMed ID: 10479356
[TBL] [Abstract][Full Text] [Related]
3. Novel prodrug approach for tertiary amines: synthesis and preliminary evaluation of N-phosphonooxymethyl prodrugs.
Krise JP; Zygmunt J; Georg GI; Stella VJ
J Med Chem; 1999 Aug; 42(16):3094-100. PubMed ID: 10447953
[TBL] [Abstract][Full Text] [Related]
4. A novel prodrug strategy for beta-dicarbonyl carbon acids: syntheses and evaluation of the physicochemical characteristics of C-phosphoryloxymethyl (POM) and phosphoryloxymethyloxymethyl (POMOM) prodrug derivatives.
Dhareshwar SS; Stella VJ
J Pharm Sci; 2010 Jun; 99(6):2711-23. PubMed ID: 20020525
[TBL] [Abstract][Full Text] [Related]
5. Preparation and physicochemical characterization of a novel water-soluble prodrug of carbamazepine.
Hemenway JN; Jarho P; Henri JT; Nair SK; VanderVelde D; Georg GI; Stella VJ
J Pharm Sci; 2010 Apr; 99(4):1810-25. PubMed ID: 19774656
[TBL] [Abstract][Full Text] [Related]
6. Chemical stability of esters of nicotinic acid intended for pulmonary administration by liquid ventilation.
Hsu CH; Jay M; Bummer PM; Lehmler HJ
Pharm Res; 2003 Jun; 20(6):918-25. PubMed ID: 12817898
[TBL] [Abstract][Full Text] [Related]
7. Modulating lipophilicity of rohitukine via prodrug approach: Preparation, characterization, and in vitro enzymatic hydrolysis in biorelevant media.
Kumar V; Bharate SS; Vishwakarma RA
Eur J Pharm Sci; 2016 Sep; 92():203-11. PubMed ID: 27422078
[TBL] [Abstract][Full Text] [Related]
8. Bioreversible quaternary N-acyloxymethyl derivatives of the tertiary amines bupivacaine and lidocaine--synthesis, aqueous solubility and stability in buffer, human plasma and simulated intestinal fluid.
Nielsen AB; Buur A; Larsen C
Eur J Pharm Sci; 2005 Apr; 24(5):433-40. PubMed ID: 15784333
[TBL] [Abstract][Full Text] [Related]
9. Long-Acting Diclofenac Ester Prodrugs for Joint Injection: Kinetics, Mechanism of Degradation, and In Vitro Release From Prodrug Suspension.
Mertz N; Larsen SW; Kristensen J; Østergaard J; Larsen C
J Pharm Sci; 2016 Oct; 105(10):3079-3087. PubMed ID: 27475785
[TBL] [Abstract][Full Text] [Related]
10. Development of water-soluble prodrugs of the HIV-1 protease inhibitor KNI-727: importance of the conversion time for higher gastrointestinal absorption of prodrugs based on spontaneous chemical cleavage.
Sohma Y; Hayashi Y; Ito T; Matsumoto H; Kimura T; Kiso Y
J Med Chem; 2003 Sep; 46(19):4124-35. PubMed ID: 12954064
[TBL] [Abstract][Full Text] [Related]
11. Morpholinoalkyl ester prodrugs of diclofenac: synthesis, in vitro and in vivo evaluation.
Tammara VK; Narurkar MM; Crider AM; Khan MA
J Pharm Sci; 1994 May; 83(5):644-8. PubMed ID: 8071813
[TBL] [Abstract][Full Text] [Related]
12. Aryl ester prodrugs of cyclic HPMPC. I: Physicochemical characterization and in vitro biological stability.
Oliyai R; Shaw JP; Sueoka-Lennen CM; Cundy KC; Arimilli MN; Jones RJ; Lee WA
Pharm Res; 1999 Nov; 16(11):1687-93. PubMed ID: 10571273
[TBL] [Abstract][Full Text] [Related]
13. Synthesis, in vitro and in vivo characterization of novel ethyl dioxy phosphate prodrug of propofol.
Kumpulainen H; Järvinen T; Mannila A; Leppänen J; Nevalainen T; Mäntylä A; Vepsäläinen J; Rautio J
Eur J Pharm Sci; 2008 Jul; 34(2-3):110-7. PubMed ID: 18403185
[TBL] [Abstract][Full Text] [Related]
14. Prodrugs of thiabendazole with increased water-solubility.
Nielsen LS; Bundgaard H; Falch E
Acta Pharm Nord; 1992; 4(1):43-9. PubMed ID: 1515051
[TBL] [Abstract][Full Text] [Related]
15. Potential improvement in the shelf life of parenterals using the prodrug approach: bacampicillin and talampicillin hydrolysis kinetics and utilization time.
Nguyen NA; Mortada LM; Notari RE
Pharm Res; 1988 May; 5(5):288-96. PubMed ID: 3244638
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis and in vitro evaluation of novel water-soluble prodrugs of buparvaquone.
Mäntylä A; Rautio J; Nevalainen T; Keski-Rahkonen P; Vepsälainen J; Järvinen T
Eur J Pharm Sci; 2004 Oct; 23(2):151-8. PubMed ID: 15451003
[TBL] [Abstract][Full Text] [Related]
17. Bioreversible quaternary N-acyloxymethyl derivatives of the poorly soluble tertiary amine Lu 28-179--synthesis, pharmaceutical chemical characterization and bioavailability studies in dogs.
Nielsen AB; Buur A; Larsen C
Eur J Pharm Sci; 2005 Dec; 26(5):421-8. PubMed ID: 16150581
[TBL] [Abstract][Full Text] [Related]
18. An improved design of water-soluble propofol prodrugs characterized by rapid onset of action.
Lang BC; Yang J; Wang Y; Luo Y; Kang Y; Liu J; Zhang WS
Anesth Analg; 2014 Apr; 118(4):745-54. PubMed ID: 24651228
[TBL] [Abstract][Full Text] [Related]
19. Enzyme-mediated precipitation of parent drugs from their phosphate prodrugs.
Heimbach T; Oh DM; Li LY; Rodríguez-Hornedo N; Garcia G; Fleisher D
Int J Pharm; 2003 Aug; 261(1-2):81-92. PubMed ID: 12878397
[TBL] [Abstract][Full Text] [Related]
20. A new amino-masking group capable of pH-triggered amino-drug release.
Gilmer JF; Simplício AL; Clancy JM
Eur J Pharm Sci; 2005 Mar; 24(4):315-23. PubMed ID: 15734298
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]