240 related articles for article (PubMed ID: 10488107)
1. New human immunodeficiency virus, type 1 reverse transcriptase (HIV-1 RT) mutants with increased fidelity of DNA synthesis. Accuracy, template binding, and processivity.
Kim B; Ayran JC; Sagar SG; Adman ET; Fuller SM; Tran NH; Horrigan J
J Biol Chem; 1999 Sep; 274(39):27666-73. PubMed ID: 10488107
[TBL] [Abstract][Full Text] [Related]
2. The processivity of DNA synthesis exhibited by drug-resistant variants of human immunodeficiency virus type-1 reverse transcriptase.
Avidan O; Hizi A
Nucleic Acids Res; 1998 Apr; 26(7):1713-7. PubMed ID: 9512543
[TBL] [Abstract][Full Text] [Related]
3. Substitutions at Phe61 in the beta3-beta4 hairpin of HIV-1 reverse transcriptase reveal a role for the Fingers subdomain in strand displacement DNA synthesis.
Fisher TS; Darden T; Prasad VR
J Mol Biol; 2003 Jan; 325(3):443-59. PubMed ID: 12498795
[TBL] [Abstract][Full Text] [Related]
4. A role for dNTP binding of human immunodeficiency virus type 1 reverse transcriptase in viral mutagenesis.
Weiss KK; Chen R; Skasko M; Reynolds HM; Lee K; Bambara RA; Mansky LM; Kim B
Biochemistry; 2004 Apr; 43(15):4490-500. PubMed ID: 15078095
[TBL] [Abstract][Full Text] [Related]
5. Fidelity of mutant HIV-1 reverse transcriptases: interaction with the single-stranded template influences the accuracy of DNA synthesis.
Kim B; Hathaway TR; Loeb LA
Biochemistry; 1998 Apr; 37(17):5831-9. PubMed ID: 9558316
[TBL] [Abstract][Full Text] [Related]
6. The effect of increased processivity on overall fidelity of human immunodeficiency virus type 1 reverse transcriptase.
Rezende LF; Kew Y; Prasad VR
J Biomed Sci; 2001; 8(2):197-205. PubMed ID: 11287751
[TBL] [Abstract][Full Text] [Related]
7. Mechanistic insights into the role of Val75 of HIV-1 reverse transcriptase in misinsertion and mispair extension fidelity of DNA synthesis.
Matamoros T; Kim B; Menéndez-Arias L
J Mol Biol; 2008 Feb; 375(5):1234-48. PubMed ID: 18155043
[TBL] [Abstract][Full Text] [Related]
8. Major groove binding track residues of the connection subdomain of human immunodeficiency virus type 1 reverse transcriptase enhance cDNA synthesis at high temperatures.
Matamoros T; Barrioluengo V; Abia D; Menéndez-Arias L
Biochemistry; 2013 Dec; 52(51):9318-28. PubMed ID: 24303887
[TBL] [Abstract][Full Text] [Related]
9. Loss of polymerase activity due to Tyr to Phe substitution in the YMDD motif of human immunodeficiency virus type-1 reverse transcriptase is compensated by Met to Val substitution within the same motif.
Harris D; Yadav PN; Pandey VN
Biochemistry; 1998 Jul; 37(27):9630-40. PubMed ID: 9657675
[TBL] [Abstract][Full Text] [Related]
10. p53 enhances the fidelity of DNA synthesis by human immunodeficiency virus type 1 reverse transcriptase.
Bakhanashvili M
Oncogene; 2001 Nov; 20(52):7635-44. PubMed ID: 11753641
[TBL] [Abstract][Full Text] [Related]
11. Molecular architecture of the mutagenic active site of human immunodeficiency virus type 1 reverse transcriptase: roles of the beta 8-alpha E loop in fidelity, processivity, and substrate interactions.
Weiss KK; Isaacs SJ; Tran NH; Adman ET; Kim B
Biochemistry; 2000 Sep; 39(35):10684-94. PubMed ID: 10978152
[TBL] [Abstract][Full Text] [Related]
12. Vertical-scanning mutagenesis of a critical tryptophan in the "minor groove binding track" of HIV-1 reverse transcriptase. Major groove DNA adducts identify specific protein interactions in the minor groove.
Latham GJ; Forgacs E; Beard WA; Prasad R; Bebenek K; Kunkel TA; Wilson SH; Lloyd RS
J Biol Chem; 2000 May; 275(20):15025-33. PubMed ID: 10747890
[TBL] [Abstract][Full Text] [Related]
13. A mutation in the primer grip region of HIV-1 reverse transcriptase that confers reduced fidelity of DNA synthesis.
Gutiérrez-Rivas M; Menéndez-Arias L
Nucleic Acids Res; 2001 Dec; 29(24):4963-72. PubMed ID: 11812826
[TBL] [Abstract][Full Text] [Related]
14. Studies on the effects of truncating alpha-helix E' of p66 human immunodeficiency virus type 1 reverse transcriptase on template-primer binding and fidelity of DNA synthesis.
Menéndez-Arias L
Biochemistry; 1998 Nov; 37(47):16636-44. PubMed ID: 9843431
[TBL] [Abstract][Full Text] [Related]
15. Role of glutamine-151 of human immunodeficiency virus type-1 reverse transcriptase in RNA-directed DNA synthesis.
Kaushik N; Harris D; Rege N; Modak MJ; Yadav PN; Pandey VN
Biochemistry; 1997 Nov; 36(47):14430-8. PubMed ID: 9398161
[TBL] [Abstract][Full Text] [Related]
16. Apparent defects in processive DNA synthesis, strand transfer, and primer elongation of Met-184 mutants of HIV-1 reverse transcriptase derive solely from a dNTP utilization defect.
Gao L; Hanson MN; Balakrishnan M; Boyer PL; Roques BP; Hughes SH; Kim B; Bambara RA
J Biol Chem; 2008 Apr; 283(14):9196-205. PubMed ID: 18218634
[TBL] [Abstract][Full Text] [Related]
17. Dominance of the E89G substitution in HIV-1 reverse transcriptase in regard to increased polymerase processivity and patterns of pausing.
Quan Y; Inouye P; Liang C; Rong L; Götte M; Wainberg MA
J Biol Chem; 1998 Aug; 273(34):21918-25. PubMed ID: 9705331
[TBL] [Abstract][Full Text] [Related]
18. Human immunodeficiency virus type 1 reverse transcriptase: role of Tyr115 in deoxynucleotide binding and misinsertion fidelity of DNA synthesis.
Martín-Hernández AM; Domingo E; Menéndez-Arias L
EMBO J; 1996 Aug; 15(16):4434-42. PubMed ID: 8861970
[TBL] [Abstract][Full Text] [Related]
19. Role of methionine 184 of human immunodeficiency virus type-1 reverse transcriptase in the polymerase function and fidelity of DNA synthesis.
Pandey VN; Kaushik N; Rege N; Sarafianos SG; Yadav PN; Modak MJ
Biochemistry; 1996 Feb; 35(7):2168-79. PubMed ID: 8652558
[TBL] [Abstract][Full Text] [Related]
20. Substitution of conserved hydrophobic residues in motifs B and C of HIV-1 RT alters the geometry of its catalytic pocket.
Sharma B; Kaushik N; Singh K; Kumar S; Pandey VN
Biochemistry; 2002 Dec; 41(52):15685-97. PubMed ID: 12501197
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
