BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 10488146)

  • 1. JAK1-dependent phosphorylation of insulin receptor substrate-1 (IRS-1) is inhibited by IRS-1 serine phosphorylation.
    Cengel KA; Freund GG
    J Biol Chem; 1999 Sep; 274(39):27969-74. PubMed ID: 10488146
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Frap-dependent serine phosphorylation of IRS-1 inhibits IRS-1 tyrosine phosphorylation.
    Hartman ME; Villela-Bach M; Chen J; Freund GG
    Biochem Biophys Res Commun; 2001 Jan; 280(3):776-81. PubMed ID: 11162588
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphatidylinositol 3'-kinase associates with an insulin receptor substrate-1 serine kinase distinct from its intrinsic serine kinase.
    Cengel KA; Kason RE; Freund GG
    Biochem J; 1998 Oct; 335 ( Pt 2)(Pt 2):397-404. PubMed ID: 9761740
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Serine/threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling.
    Tanti JF; Grémeaux T; van Obberghen E; Le Marchand-Brustel Y
    J Biol Chem; 1994 Feb; 269(8):6051-7. PubMed ID: 8119950
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase.
    De Fea K; Roth RA
    J Biol Chem; 1997 Dec; 272(50):31400-6. PubMed ID: 9395471
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.
    Batty IH; Fleming IN; Downes CP
    Biochem J; 2004 May; 379(Pt 3):641-51. PubMed ID: 14769130
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The type I interferon receptor mediates tyrosine phosphorylation of insulin receptor substrate 2.
    Platanias LC; Uddin S; Yetter A; Sun XJ; White MF
    J Biol Chem; 1996 Jan; 271(1):278-82. PubMed ID: 8550573
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modulation of insulin-stimulated degradation of human insulin receptor substrate-1 by Serine 312 phosphorylation.
    Greene MW; Sakaue H; Wang L; Alessi DR; Roth RA
    J Biol Chem; 2003 Mar; 278(10):8199-211. PubMed ID: 12510059
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interferon-dependent activation of the serine kinase PI 3'-kinase requires engagement of the IRS pathway but not the Stat pathway.
    Uddin S; Majchrzak B; Wang PC; Modi S; Khan MK; Fish EN; Platanias LC
    Biochem Biophys Res Commun; 2000 Apr; 270(1):158-62. PubMed ID: 10733921
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Janus kinase-dependent activation of insulin receptor substrate 1 in response to interleukin-4, oncostatin M, and the interferons.
    Burfoot MS; Rogers NC; Watling D; Smith JM; Pons S; Paonessaw G; Pellegrini S; White MF; Kerr IM
    J Biol Chem; 1997 Sep; 272(39):24183-90. PubMed ID: 9305869
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphorylation of insulin receptor substrate-1 on multiple serine residues, 612, 632, 662, and 731, modulates insulin action.
    Mothe I; Van Obberghen E
    J Biol Chem; 1996 May; 271(19):11222-7. PubMed ID: 8626671
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphorylation of Ser24 in the pleckstrin homology domain of insulin receptor substrate-1 by Mouse Pelle-like kinase/interleukin-1 receptor-associated kinase: cross-talk between inflammatory signaling and insulin signaling that may contribute to insulin resistance.
    Kim JA; Yeh DC; Ver M; Li Y; Carranza A; Conrads TP; Veenstra TD; Harrington MA; Quon MJ
    J Biol Chem; 2005 Jun; 280(24):23173-83. PubMed ID: 15849359
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Positive and negative regulatory role of insulin receptor substrate 1 and 2 (IRS-1 and IRS-2) serine/threonine phosphorylation.
    Greene MW; Garofalo RS
    Biochemistry; 2002 Jun; 41(22):7082-91. PubMed ID: 12033942
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 14-3-3 facilitates insulin-stimulated intracellular trafficking of insulin receptor substrate 1.
    Xiang X; Yuan M; Song Y; Ruderman N; Wen R; Luo Z
    Mol Endocrinol; 2002 Mar; 16(3):552-62. PubMed ID: 11875115
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.
    Ozes ON; Akca H; Mayo LD; Gustin JA; Maehama T; Dixon JE; Donner DB
    Proc Natl Acad Sci U S A; 2001 Apr; 98(8):4640-5. PubMed ID: 11287630
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Active Rho kinase (ROK-alpha ) associates with insulin receptor substrate-1 and inhibits insulin signaling in vascular smooth muscle cells.
    Begum N; Sandu OA; Ito M; Lohmann SM; Smolenski A
    J Biol Chem; 2002 Feb; 277(8):6214-22. PubMed ID: 11739394
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression and function of IRS-1 in insulin signal transmission.
    Sun XJ; Miralpeix M; Myers MG; Glasheen EM; Backer JM; Kahn CR; White MF
    J Biol Chem; 1992 Nov; 267(31):22662-72. PubMed ID: 1385403
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tumor necrosis factor alpha-induced phosphorylation of insulin receptor substrate-1 (IRS-1). Possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1.
    Kanety H; Feinstein R; Papa MZ; Hemi R; Karasik A
    J Biol Chem; 1995 Oct; 270(40):23780-4. PubMed ID: 7559552
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Growth hormone and prolactin stimulate tyrosine phosphorylation of insulin receptor substrate-1, -2, and -3, their association with p85 phosphatidylinositol 3-kinase (PI3-kinase), and concomitantly PI3-kinase activation via JAK2 kinase.
    Yamauchi T; Kaburagi Y; Ueki K; Tsuji Y; Stark GR; Kerr IM; Tsushima T; Akanuma Y; Komuro I; Tobe K; Yazaki Y; Kadowaki T
    J Biol Chem; 1998 Jun; 273(25):15719-26. PubMed ID: 9624169
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insulin receptor substrate-1 as a signaling molecule for focal adhesion kinase pp125(FAK) and pp60(src).
    Lebrun P; Mothe-Satney I; Delahaye L; Van Obberghen E; Baron V
    J Biol Chem; 1998 Nov; 273(48):32244-53. PubMed ID: 9822703
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.