102 related articles for article (PubMed ID: 10489446)
1. Crystal structure of epidoxorubicin-formaldehyde virtual crosslink of DNA and evidence for its formation in human breast-cancer cells.
Podell ER; Harrington DJ; Taatjes DJ; Koch TH
Acta Crystallogr D Biol Crystallogr; 1999 Sep; 55(Pt 9):1516-23. PubMed ID: 10489446
[TBL] [Abstract][Full Text] [Related]
2. Epidoxoform: a hydrolytically more stable anthracycline-formaldehyde conjugate toxic to resistant tumor cells.
Taatjes DJ; Fenick DJ; Koch TH
J Med Chem; 1998 Apr; 41(8):1306-14. PubMed ID: 9548820
[TBL] [Abstract][Full Text] [Related]
3. Nuclear targeting and nuclear retention of anthracycline-formaldehyde conjugates implicates DNA covalent bonding in the cytotoxic mechanism of anthracyclines.
Taatjes DJ; Fenick DJ; Koch TH
Chem Res Toxicol; 1999 Jul; 12(7):588-96. PubMed ID: 10409398
[TBL] [Abstract][Full Text] [Related]
4. Facile formation of a crosslinked adduct between DNA and the daunorubicin derivative MAR70 mediated by formaldehyde: molecular structure of the MAR70-d(CGTnACG) covalent adduct.
Gao YG; Liaw YC; Li YK; van der Marel GA; van Boom JH; Wang AH
Proc Natl Acad Sci U S A; 1991 Jun; 88(11):4845-9. PubMed ID: 2052564
[TBL] [Abstract][Full Text] [Related]
5. Nuclear targeting and retention of anthracycline antitumor drugs in sensitive and resistant tumor cells.
Taatjes DJ; Koch TH
Curr Med Chem; 2001 Jan; 8(1):15-29. PubMed ID: 11172689
[TBL] [Abstract][Full Text] [Related]
6. Simultaneous incorporations of two anticancer drugs into DNA. The structures of formaldehyde-cross-linked adducts of daunorubicin-d(CG(araC)GCG) and doxorubicin-d(CA(araC)GTG) complexes at high resolution.
Zhang H; Gao YG; van der Marel GA; van Boom JH; Wang AH
J Biol Chem; 1993 May; 268(14):10095-101. PubMed ID: 8486678
[TBL] [Abstract][Full Text] [Related]
7. Binding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[br5C]CG complexes.
Dutta R; Gao YG; Priebe W; Wang AH
Nucleic Acids Res; 1998 Jun; 26(12):3001-5. PubMed ID: 9611247
[TBL] [Abstract][Full Text] [Related]
8. Substitutions at C2' of daunosamine in the anticancer drug daunorubicin alter its DNA-binding sequence specificity.
Gao YG; Priebe W; Wang AH
Eur J Biochem; 1996 Sep; 240(2):331-5. PubMed ID: 8841395
[TBL] [Abstract][Full Text] [Related]
9. Growth inhibition, nuclear uptake, and retention of anthracycline-formaldehyde conjugates in prostate cancer cells relative to clinical anthracyclines.
Taatjes DJ; Koch TH
Anticancer Res; 1999; 19(2A):1201-8. PubMed ID: 10368676
[TBL] [Abstract][Full Text] [Related]
10. Doxoform and Daunoform: anthracycline-formaldehyde conjugates toxic to resistant tumor cells.
Fenick DJ; Taatjes DJ; Koch TH
J Med Chem; 1997 Aug; 40(16):2452-61. PubMed ID: 9258351
[TBL] [Abstract][Full Text] [Related]
11. Evaluation of the epidoxorubicin--formaldehyde conjugate, epidoxoform, in a mouse mammary carcinoma model.
Dernell WS; Powers BE; Taatjes DJ; Cogan P; Gaudiano G; Koch TH
Cancer Invest; 2002; 20(5-6):713-24. PubMed ID: 12197227
[TBL] [Abstract][Full Text] [Related]
12. Formaldehyde cross-links daunorubicin and DNA efficiently: HPLC and X-ray diffraction studies.
Wang AH; Gao YG; Liaw YC; Li YK
Biochemistry; 1991 Apr; 30(16):3812-5. PubMed ID: 2018756
[TBL] [Abstract][Full Text] [Related]
13. Mass spectrometric measurement of formaldehyde generated in breast cancer cells upon treatment with anthracycline antitumor drugs.
Kato S; Burke PJ; Fenick DJ; Taatjes DJ; Bierbaum VM; Koch TH
Chem Res Toxicol; 2000 Jun; 13(6):509-16. PubMed ID: 10858324
[TBL] [Abstract][Full Text] [Related]
14. Structure-based design of a new bisintercalating anthracycline antibiotic.
Chaires JB; Leng F; Przewloka T; Fokt I; Ling YH; Perez-Soler R; Priebe W
J Med Chem; 1997 Jan; 40(3):261-6. PubMed ID: 9022792
[TBL] [Abstract][Full Text] [Related]
15. Redox pathway leading to the alkylation of DNA by the anthracycline, antitumor drugs adriamycin and daunomycin.
Taatjes DJ; Gaudiano G; Resing K; Koch TH
J Med Chem; 1997 Apr; 40(8):1276-86. PubMed ID: 9111302
[TBL] [Abstract][Full Text] [Related]
16. The hydroxyl epimer of doxorubicin controls the rate of formation of cytotoxic anthracycline-DNA adducts.
Forrest RA; Swift LP; Evison BJ; Rephaeli A; Nudelman A; Phillips DR; Cutts SM
Cancer Chemother Pharmacol; 2013 Mar; 71(3):809-16. PubMed ID: 23263186
[TBL] [Abstract][Full Text] [Related]
17. Production of formaldehyde and DNA-adriamycin or DNA-daunomycin adducts, initiated through redox chemistry of dithiothreitol/iron, xanthine oxidase/NADH/iron, or glutathione/iron.
Taatjes DJ; Gaudiano G; Koch TH
Chem Res Toxicol; 1997 Sep; 10(9):953-61. PubMed ID: 9305576
[TBL] [Abstract][Full Text] [Related]
18. Binding of two novel bisdaunorubicins to DNA studied by NMR spectroscopy.
Robinson H; Priebe W; Chaires JB; Wang AH
Biochemistry; 1997 Jul; 36(29):8663-70. PubMed ID: 9289011
[TBL] [Abstract][Full Text] [Related]
19. Release of the cyano moiety in the crystal structure of N-cyanomethyl-N-(2-methoxyethyl)-daunomycin complexed with d(CGATCG).
Saminadin P; Dautant A; Mondon M; Langlois D'estaintot B; Courseille C; Précigoux G
Eur J Biochem; 2000 Jan; 267(2):457-64. PubMed ID: 10632715
[TBL] [Abstract][Full Text] [Related]
20. Correlation of in Situ Oxazolidine Formation with Highly Synergistic Cytotoxicity and DNA Cross-Linking in Cancer Cells from Combinations of Doxorubicin and Formaldehyde.
Barthel BL; Mooz EL; Wiener LE; Koch GG; Koch TH
J Med Chem; 2016 Mar; 59(5):2205-21. PubMed ID: 26881291
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]