BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 10489539)

  • 1. Synthesis and biological evaluation of butanoate, retinoate, and bis(2,2,2-trichloroethyl)phosphate derivatives of 5-fluoro-2'-deoxyuridine and 2',5-difluoro-2'-deoxyuridine as potential dual action anticancer prodrugs.
    Xia Z; Wiebe LI; Miller GG; Knaus EE
    Arch Pharm (Weinheim); 1999 Aug; 332(8):286-94. PubMed ID: 10489539
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and anticancer activities of amphiphilic 5-fluoro-2'-deoxyuridylic acid prodrugs.
    Ludwig PS; Schwendener RA; Schott H
    Eur J Med Chem; 2005 May; 40(5):494-504. PubMed ID: 15893023
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New 3'-O-aromatic acyl-5-fluoro-2'-deoxyuridine derivatives as potential anticancer agents.
    Szymańska-Michalak A; Wawrzyniak D; Framski G; Kujda M; Zgoła P; Stawinski J; Barciszewski J; Boryski J; Kraszewski A
    Eur J Med Chem; 2016 Jun; 115():41-52. PubMed ID: 26994842
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel anticancer polymeric conjugates of activated nucleoside analogues.
    Senanayake TH; Warren G; Vinogradov SV
    Bioconjug Chem; 2011 Oct; 22(10):1983-93. PubMed ID: 21863885
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Antisense oligonucleotides with antitumor activity].
    Otvös L; Sági G
    Magy Onkol; 2004; 48(3):221-7. PubMed ID: 15520872
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological activity of novel 5-fluoro-2'-deoxyuridine phosphoramidate prodrugs.
    Freel Meyers CL; Hong L; Joswig C; Borch RF
    J Med Chem; 2000 Nov; 43(22):4313-8. PubMed ID: 11063625
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The novel heterodinucleoside dimer 5-FdU-NOAC is a potent cytotoxic drug and a p53-independent inducer of apoptosis in the androgen-independent human prostate cancer cell lines PC-3 and DU-145.
    Cattaneo-Pangrazzi RM; Schott H; Schwendener RA
    Prostate; 2000 Sep; 45(1):8-18. PubMed ID: 10960838
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hypoxia-Activated and Indomethacin-Mediated Theranostic Prodrug Releasing Drug On-Demand for Tumor Imaging and Therapy.
    Peng X; Gao J; Yuan Y; Liu H; Lei W; Li S; Zhang J; Wang S
    Bioconjug Chem; 2019 Nov; 30(11):2828-2843. PubMed ID: 31592652
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacokinetics of 3'-O-retinoyl-5-fluoro-2'-deoxyuridine (RFUdR), a dual acting mutually masking prodrug, and its metabolites in tumor bearing mice.
    Xia Z; Knaus EE; Wiebe LI
    Curr Drug Deliv; 2013 Oct; 10(5):557-63. PubMed ID: 23755721
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Liposome-incorporated 3',5'-O-dipalmitoyl-5-fluoro-2'-deoxyuridine as a slow-release anti-tumor drug depot in rat liver macrophages.
    Van Borssum Waalkes M; Scherphof GL
    Sel Cancer Ther; 1990; 6(1):15-22. PubMed ID: 2140463
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological activity of O-alkyl-3-N-aminoacyloxymethyl-5-fluoro-2'-deoxyuridine derivatives.
    Harada N; Hongu M; Kawaguchi T; Ohohashi M; Oda K; Hashiyama T; Tsujihara K
    Chem Pharm Bull (Tokyo); 1996 Jun; 44(6):1196-201. PubMed ID: 8814951
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vitro and in vivo evaluation of novel antitumor prodrugs of 5-fluoro-2'-deoxyuridine activated by hypoxic irradiation.
    Shibamoto Y; Tachi Y; Tanabe K; Hatta H; Nishimoto S
    Int J Radiat Oncol Biol Phys; 2004 Feb; 58(2):397-402. PubMed ID: 14751508
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and biological activity of N-2,3-dihydroxypropyl-N-4-chlorobutyl nucleoside phosphoramidate prodrugs.
    Wu W; Borch RF
    Mol Pharm; 2006; 3(4):451-6. PubMed ID: 16889439
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sulfonyl-containing nucleoside phosphotriesters and phosphoramidates as novel anticancer prodrugs of 5-fluoro-2'-deoxyuridine 5'-monophosphate (FdUMP).
    Sun YW; Chen KM; Kwon CH
    Mol Pharm; 2006; 3(2):161-73. PubMed ID: 16579645
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and SAR of 2',3'-bis-O-substituted N(6), 5'-bis-ureidoadenosine derivatives: implications for prodrug delivery and mechanism of action.
    Shelton JR; Cutler CE; Browning MS; Balzarini J; Peterson MA
    Bioorg Med Chem Lett; 2012 Oct; 22(19):6067-71. PubMed ID: 22959517
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of 2'-deoxyuridine and 5-fluoro-2'-deoxyuridine derivatives and evaluation in antibody targeting studies.
    Henn TF; Garnett MC; Chhabra SR; Bycroft BW; Baldwin RW
    J Med Chem; 1993 May; 36(11):1570-9. PubMed ID: 8496926
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel approaches for designing 5'-O-ester prodrugs of 3'-azido-2', 3'-dideoxythymidine (AZT).
    Parang K; Wiebe LI; Knaus EE
    Curr Med Chem; 2000 Oct; 7(10):995-1039. PubMed ID: 10911016
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel mutual prodrug of retinoic and butyric acids with enhanced anticancer activity.
    Nudelman A; Rephaeli A
    J Med Chem; 2000 Jul; 43(15):2962-6. PubMed ID: 10956204
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hypoxia-Activated Anticancer Prodrug for Bioimaging, Tracking Drug Release, and Anticancer Application.
    Liu W; Liu H; Peng X; Zhou G; Liu D; Li S; Zhang J; Wang S
    Bioconjug Chem; 2018 Oct; 29(10):3332-3343. PubMed ID: 30192132
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and preliminary in vitro screening of lipophilic alpha, gamma-bis(amides) as potential prodrugs of methotrexate.
    Pignatello R; Sorrenti V; Spampinato G; Pecora T; Panico A; Di Giacomo C; Fresta M; Vanella A; Puglisi G
    Anticancer Drug Des; 1996 Apr; 11(3):253-64. PubMed ID: 8663912
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.