BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

250 related articles for article (PubMed ID: 10493511)

  • 1. Targeting sigma receptor-binding benzamides as in vivo diagnostic and therapeutic agents for human prostate tumors.
    John CS; Vilner BJ; Geyer BC; Moody T; Bowen WD
    Cancer Res; 1999 Sep; 59(18):4578-83. PubMed ID: 10493511
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis, in vitro pharmacologic characterization, and preclinical evaluation of N-[2-(1'-piperidinyl)ethyl]-3-[125I]iodo-4-methoxybenzamide (P[125I]MBA) for imaging breast cancer.
    John CS; Bowen WD; Fisher SJ; Lim BB; Geyer BC; Vilner BJ; Wahl RL
    Nucl Med Biol; 1999 May; 26(4):377-82. PubMed ID: 10382840
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sigma-1 and sigma-2 receptors are expressed in a wide variety of human and rodent tumor cell lines.
    Vilner BJ; John CS; Bowen WD
    Cancer Res; 1995 Jan; 55(2):408-13. PubMed ID: 7812973
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, in vitro binding, and tissue distribution of radioiodinated 2-[125I]N-(N-benzylpiperidin-4-yl)-2-iodo benzamide, 2-[125I]BP: a potential sigma receptor marker for human prostate tumors.
    John CS; Gulden ME; Li J; Bowen WD; McAfee JG; Thakur ML
    Nucl Med Biol; 1998 Apr; 25(3):189-94. PubMed ID: 9620622
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and pharmacological characterization of 4-[125I]-N-(N-benzylpiperidin-4-yl)-4-iodobenzamide: a high affinity sigma receptor ligand for potential imaging of breast cancer.
    John CS; Vilner BJ; Gulden ME; Efange SM; Langason RB; Moody TW; Bowen WD
    Cancer Res; 1995 Jul; 55(14):3022-7. PubMed ID: 7606722
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [3H]N-[4-(3,4-dihydro-6,7-dimethoxyisoquinolin-2(1H)-yl)butyl]-2-methoxy-5-methylbenzamide: a novel sigma-2 receptor probe.
    Xu J; Tu Z; Jones LA; Vangveravong S; Wheeler KT; Mach RH
    Eur J Pharmacol; 2005 Nov; 525(1-3):8-17. PubMed ID: 16289030
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Substituted halogenated arylsulfonamides: a new class of sigma receptor binding tumor imaging agents.
    John CS; Lim BB; Vilner BJ; Geyer BC; Bowen WD
    J Med Chem; 1998 Jul; 41(14):2445-50. PubMed ID: 9651150
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rat liver and kidney contain high densities of sigma 1 and sigma 2 receptors: characterization by ligand binding and photoaffinity labeling.
    Hellewell SB; Bruce A; Feinstein G; Orringer J; Williams W; Bowen WD
    Eur J Pharmacol; 1994 Jun; 268(1):9-18. PubMed ID: 7925616
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vitro characterization of radioiodinated (+)-2-[4-(4-iodophenyl) piperidino]cyclohexanol [(+)-pIV] as a sigma-1 receptor ligand.
    Shiba K; Ogawa K; Mori H
    Bioorg Med Chem; 2005 Feb; 13(4):1095-9. PubMed ID: 15670917
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis, in vitro validation and in vivo pharmacokinetics of [125I]N-[2-(4-iodophenyl)ethyl]-N-methyl-2-(1-piperidinyl) ethylamine: a high-affinity ligand for imaging sigma receptor positive tumors.
    John CS; Gulden ME; Vilner BJ; Bowen WD
    Nucl Med Biol; 1996 Aug; 23(6):761-6. PubMed ID: 8940718
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of a novel iodinated sigma-2 receptor ligand as a cell proliferation marker.
    Hou C; Tu Z; Mach R; Kung HF; Kung MP
    Nucl Med Biol; 2006 Feb; 33(2):203-9. PubMed ID: 16546674
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Radioiodination and preclinical evaluation of 4-benzyl-1-(3-[
    Sadeghzadeh M; Alirezapour B; Charkhlooie GA; Baghery MK; Khorouti A
    Ann Nucl Med; 2017 May; 31(4):335-346. PubMed ID: 28315150
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Flavopiridol (L86-8275): selective antitumor activity in vitro and activity in vivo for prostate carcinoma cells.
    Drees M; Dengler WA; Roth T; Labonte H; Mayo J; Malspeis L; Grever M; Sausville EA; Fiebig HH
    Clin Cancer Res; 1997 Feb; 3(2):273-9. PubMed ID: 9815683
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of human prostate cancer xenograft growth by 125I labeled triple-helix forming oligonucleotide directed against androgen receptor.
    Zhang Y; Ma Y; Lu HP; Gao JH; Liang CS; Liu CZ; Zou JT; Wang HQ
    Chin Med J (Engl); 2008 Nov; 121(22):2284-9. PubMed ID: 19080333
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Halogenated 4-(phenoxymethyl)piperidines as potential radiolabeled probes for sigma-1 receptors: in vivo evaluation of [123I]-1-(iodopropen-2-yl)-4-[(4-cyanophenoxy)methyl]pip eri dine.
    Waterhouse RN; Mardon K; Giles KM; Collier TL; O'Brien JC
    J Med Chem; 1997 May; 40(11):1657-67. PubMed ID: 9171875
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design and Investigation of a [
    Yang D; Comeau A; Bowen WD; Mach RH; Ross BD; Hong H; Van Dort ME
    Mol Pharm; 2017 Mar; 14(3):770-780. PubMed ID: 28135101
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and characterization of [¹²⁵I]2-iodo N-[(S)-{(S)-1-methylpiperidin-2-yl}(phenyl)methyl]3-trifluoromethyl-benzamide as novel imaging probe for glycine transporter 1.
    Fuchigami T; Haratake M; Magata Y; Haradahira T; Nakayama M
    Bioorg Med Chem; 2011 Nov; 19(21):6245-53. PubMed ID: 21975065
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Small molecule antagonists of the sigma-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo.
    Spruce BA; Campbell LA; McTavish N; Cooper MA; Appleyard MV; O'Neill M; Howie J; Samson J; Watt S; Murray K; McLean D; Leslie NR; Safrany ST; Ferguson MJ; Peters JA; Prescott AR; Box G; Hayes A; Nutley B; Raynaud F; Downes CP; Lambert JJ; Thompson AM; Eccles S
    Cancer Res; 2004 Jul; 64(14):4875-86. PubMed ID: 15256458
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [3H]1-(cyclopropylmethyl)-4-(2-(4-fluorophenyl)-2-oxoethyl) piperidine HBr (DuP 734). A selective ligand for sigma receptors in mouse brain in vivo.
    Watanabe M; Rominger D; Hurt SD; De Souza EB; Tam SW
    J Pharmacol Exp Ther; 1993 Sep; 266(3):1541-8. PubMed ID: 8371156
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 177Lu-AMBA: Synthesis and characterization of a selective 177Lu-labeled GRP-R agonist for systemic radiotherapy of prostate cancer.
    Lantry LE; Cappelletti E; Maddalena ME; Fox JS; Feng W; Chen J; Thomas R; Eaton SM; Bogdan NJ; Arunachalam T; Reubi JC; Raju N; Metcalfe EC; Lattuada L; Linder KE; Swenson RE; Tweedle MF; Nunn AD
    J Nucl Med; 2006 Jul; 47(7):1144-52. PubMed ID: 16818949
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.