These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

78 related articles for article (PubMed ID: 10499129)

  • 21. Novel dihydrofolate reductase inhibitors. Structure-based versus diversity-based library design and high-throughput synthesis and screening.
    Wyss PC; Gerber P; Hartman PG; Hubschwerlen C; Locher H; Marty HP; Stahl M
    J Med Chem; 2003 Jun; 46(12):2304-12. PubMed ID: 12773035
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Screening for xenobiotic electrophilic metabolites using pulsed ultrafiltration-mass spectrometry.
    Nikolic D; Fan PW; Bolton JL; van Breemen RB
    Comb Chem High Throughput Screen; 1999 Jun; 2(3):165-75. PubMed ID: 10420970
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Multiple ligand detection and affinity measurement by ultrafiltration and mass spectrometry analysis applied to fragment mixture screening.
    Qin S; Ren Y; Fu X; Shen J; Chen X; Wang Q; Bi X; Liu W; Li L; Liang G; Yang C; Shui W
    Anal Chim Acta; 2015 Jul; 886():98-106. PubMed ID: 26320641
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Affinity selection-mass spectrometry for the discovery of pharmacologically active compounds from combinatorial libraries and natural products.
    Muchiri RN; van Breemen RB
    J Mass Spectrom; 2021; 56(5):e4647. PubMed ID: 32955158
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Calorimetric studies of ligand binding in R67 dihydrofolate reductase.
    Jackson M; Chopra S; Smiley RD; Maynord PO; Rosowsky A; London RE; Levy L; Kalman TI; Howell EE
    Biochemistry; 2005 Sep; 44(37):12420-33. PubMed ID: 16156655
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Elevation of dihydrofolate reductase, thymidylate synthetase, and thymidine kinase in cultured mammalian cells after exposure to folate antagonists.
    Chello PL; McQueen CA; DeAngelis LM; Bertino JR
    Cancer Res; 1976 Jul; 36(7 PT 1):2442-9. PubMed ID: 1277151
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Development of a Magnetic Microbead Affinity Selection Screen (MagMASS) Using Mass Spectrometry for Ligands to the Retinoid X Receptor-α.
    Rush MD; Walker EM; Prehna G; Burton T; van Breemen RB
    J Am Soc Mass Spectrom; 2017 Mar; 28(3):479-485. PubMed ID: 27966173
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Dicyclic and tricyclic diaminopyrimidine derivatives as potent inhibitors of Cryptosporidium parvum dihydrofolate reductase: structure-activity and structure-selectivity correlations.
    Nelson RG; Rosowsky A
    Antimicrob Agents Chemother; 2001 Dec; 45(12):3293-303. PubMed ID: 11709300
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase.
    Jolivet J; Chabner BA
    J Clin Invest; 1983 Sep; 72(3):773-8. PubMed ID: 6193143
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Development of binding assays to screen ligands for Plasmodium falciparum thioredoxin and glutathione reductases by ultrafiltration and liquid chromatography/mass spectrometry.
    Mulabagal V; Calderón AI
    J Chromatogr B Analyt Technol Biomed Life Sci; 2010 Apr; 878(13-14):987-93. PubMed ID: 20335080
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Affinity selection and mass spectrometry-based strategies to identify lead compounds in combinatorial libraries.
    Kaur S; McGuire L; Tang D; Dollinger G; Huebner V
    J Protein Chem; 1997 Jul; 16(5):505-11. PubMed ID: 9246636
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Capillary-scale frontal affinity chromatography/MALDI tandem mass spectrometry using protein-doped monolithic silica columns.
    Kovarik P; Hodgson RJ; Covey T; Brook MA; Brennan JD
    Anal Chem; 2005 May; 77(10):3340-50. PubMed ID: 15889927
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Neisseriaceae, a group of bacteria with dihydrofolate reductases, moderately susceptible to trimethoprim.
    Then RL
    Zentralbl Bakteriol Orig A; 1979 Dec; 245(4):450-8. PubMed ID: 44939
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Screening solution-phase combinatorial libraries using pulsed ultrafiltration/electrospray mass spectrometry.
    Zhao YZ; van Breemen RB; Nikolic D; Huang CR; Woodbury CP; Schilling A; Venton DL
    J Med Chem; 1997 Dec; 40(25):4006-12. PubMed ID: 9406591
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Virtual ligand screening against Escherichia coli dihydrofolate reductase: improving docking enrichment using physics-based methods.
    Bernacki K; Kalyanaraman C; Jacobson MP
    J Biomol Screen; 2005 Oct; 10(7):675-81. PubMed ID: 16170049
    [TBL] [Abstract][Full Text] [Related]  

  • 36. An expedient and facile one-step synthesis of a biguanide library by microwave irradiation coupled with simple product filtration. Inhibitors of dihydrofolate reductase.
    Mayer S; Daigle DM; Brown ED; Khatri J; Organ MG
    J Comb Chem; 2004; 6(5):776-82. PubMed ID: 15360213
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Consideration of the pH-dependent inhibition of dihydrofolate reductase by methotrexate.
    Cannon WR; Garrison BJ; Benkovic SJ
    J Mol Biol; 1997 Aug; 271(4):656-68. PubMed ID: 9281432
    [TBL] [Abstract][Full Text] [Related]  

  • 38. In silico screening against wild-type and mutant Plasmodium falciparum dihydrofolate reductase.
    Fogel GB; Cheung M; Pittman E; Hecht D
    J Mol Graph Model; 2008 Apr; 26(7):1145-52. PubMed ID: 18037315
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Dihydrofolate reductase from Trypanosoma equiperdum. I. Isolation, partial purification, and properties.
    Jaffe JJ; McCormack JJ
    Mol Pharmacol; 1967 Jul; 3(4):359-69. PubMed ID: 4382281
    [No Abstract]   [Full Text] [Related]  

  • 40. Toxicity of methotrexate and metoprine in a dihydrofolate reductase gene-amplified mouse cell line.
    Hamrell M; Laszlo J; Brown OE; Sedwick WD
    Mol Pharmacol; 1981 Nov; 20(3):637-43. PubMed ID: 7329406
    [No Abstract]   [Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 4.