BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

139 related articles for article (PubMed ID: 10500503)

  • 1. Dimeric analogues of non-cationic tricyclic aromatic carboxamides are a new class of cytotoxic agents.
    Spicer JA; Gamage SA; Atwell GJ; Finlay GJ; Baguley BC; Denny WA
    Anticancer Drug Des; 1999 Jun; 14(3):281-9. PubMed ID: 10500503
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-activity relationships for substituted bis(acridine-4-carboxamides): a new class of anticancer agents.
    Gamage SA; Spicer JA; Atwell GJ; Finlay GJ; Baguley BC; Denny WA
    J Med Chem; 1999 Jul; 42(13):2383-93. PubMed ID: 10395479
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bis(phenazine-1-carboxamides): structure-activity relationships for a new class of dual topoisomerase I/II-directed anticancer drugs.
    Spicer JA; Gamage SA; Rewcastle GW; Finlay GJ; Bridewell DJ; Baguley BC; Denny WA
    J Med Chem; 2000 Apr; 43(7):1350-8. PubMed ID: 10753472
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and biological evaluation of phenanthrene-derived carboxamides as cytotoxic agents.
    Cherubim P; Deady LW; Dorkos M; Quazi NH; Baguley BC; Denny WA
    Anticancer Drug Des; 1993 Dec; 8(6):429-38. PubMed ID: 8286011
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-activity relationships for acridine-substituted analogues of the mixed topoisomerase I/II inhibitor N-[2-(dimethylamino)ethyl]acridine-4-carboxamide.
    Spicer JA; Gamage SA; Atwell GJ; Finlay GJ; Baguley BC; Denny WA
    J Med Chem; 1997 Jun; 40(12):1919-29. PubMed ID: 9191970
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, and biological properties of new bis(acridine-4-carboxamides) as anticancer agents.
    Antonini I; Polucci P; Magnano A; Gatto B; Palumbo M; Menta E; Pescalli N; Martelli S
    J Med Chem; 2003 Jul; 46(14):3109-15. PubMed ID: 12825949
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rational design, synthesis, and biological evaluation of bis(pyrimido[5,6,1-de]acridines) and bis(pyrazolo[3,4,5-kl]acridine-5-carboxamides) as new anticancer agents.
    Antonini I; Polucci P; Magnano A; Sparapani S; Martelli S
    J Med Chem; 2004 Oct; 47(21):5244-50. PubMed ID: 15456268
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of mono- and bisdihydrodipyridopyrazines and assessment of their DNA binding and cytotoxic properties.
    Blanchard S; Rodriguez I; Tardy C; Baldeyrou B; Bailly C; Colson P; Houssier C; Léonce S; Kraus-Berthier L; Pfeiffer B; Renard P; Pierré A; Caubère P; Guillaumet G
    J Med Chem; 2004 Feb; 47(4):978-87. PubMed ID: 14761199
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and cytotoxic activity of carboxamide derivatives of benzo[b][1,6]naphthyridines.
    Deady LW; Rodemann T; Zhuang L; Baguley BC; Denny WA
    J Med Chem; 2003 Mar; 46(6):1049-54. PubMed ID: 12620081
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and antitumor properties of N-[2-(dimethylamino)ethyl]carboxamide derivatives of fused tetracyclic quinolines and quinoxalines: a new class of putative topoisomerase inhibitors.
    Deady LW; Kaye AJ; Finlay GJ; Baguley BC; Denny WA
    J Med Chem; 1997 Jun; 40(13):2040-6. PubMed ID: 9207945
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phenazine-1-carboxamides: structure-cytotoxicity relationships for 9-substituents and changes in the H-bonding pattern of the cationic side chain.
    Gamage SA; Rewcastle GW; Baguley BC; Charlton PA; Denny WA
    Bioorg Med Chem; 2006 Feb; 14(4):1160-8. PubMed ID: 16216514
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 5,7-Disubstituted analogues of the mixed topoisomerase I/II poison N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA): DNA binding and patterns of cytotoxicity.
    Spicer JA; Finlay GJ; Baguley BC; Velea L; Graves DE; Denny WA
    Anticancer Drug Des; 1999 Feb; 14(1):37-45. PubMed ID: 10363026
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparative biodistribution and metabolism of carbon-11-labeled N-[2-(dimethylamino)ethyl]acridine-4-carboxamide and DNA-intercalating analogues.
    Osman S; Rowlinson-Busza G; Luthra SK; Aboagye EO; Brown GD; Brady F; Myers R; Gamage SA; Denny WA; Baguley BC; Price PM
    Cancer Res; 2001 Apr; 61(7):2935-44. PubMed ID: 11306471
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dicationic bis(9-methylphenazine-1-carboxamides): relationships between biological activity and linker chain structure for a series of potent topoisomerase targeted anticancer drugs.
    Gamage SA; Spicer JA; Finlay GJ; Stewart AJ; Charlton P; Baguley BC; Denny WA
    J Med Chem; 2001 Apr; 44(9):1407-15. PubMed ID: 11311063
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and antitumor activity of some indeno[1,2-b]quinoline-based bis carboxamides.
    Deady LW; Desneves J; Kaye AJ; Finlay GJ; Baguley BC; Denny WA
    Bioorg Med Chem; 2000 May; 8(5):977-84. PubMed ID: 10882009
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel antitumor agent family of 1H-benzo[c,d]indol-2-one with flexible basic side chains: synthesis and biological evaluation.
    Yin H; Xu Y; Qian X
    Bioorg Med Chem; 2007 Feb; 15(3):1356-62. PubMed ID: 17129733
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Potential antitumor agents. 55. 6-Phenylphenanthridine-4-carboxamides: a new class of DNA-intercalating antitumor agents.
    Atwell GJ; Baguley BC; Denny WA
    J Med Chem; 1988 Apr; 31(4):774-9. PubMed ID: 3351855
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and antitumor activity of 4-aminomethylthioxanthenone and 5-aminomethylbenzothiopyranoindazole derivatives.
    Perni RB; Wentland MP; Huang JI; Powles RG; Aldous S; Klingbeil KM; Peverly AD; Robinson RG; Corbett TH; Jones JL; Mattes KC; Rake JB; Coughlin SA
    J Med Chem; 1998 Sep; 41(19):3645-54. PubMed ID: 9733489
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and cytotoxic activity of carboxamide derivatives of benzo[b][1,6]naphthyridin-(5H)ones.
    Deady LW; Rogers ML; Zhuang L; Baguley BC; Denny WA
    Bioorg Med Chem; 2005 Feb; 13(4):1341-55. PubMed ID: 15670942
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New analogues of amonafide and elinafide, containing aromatic heterocycles: synthesis, antitumor activity, molecular modeling, and DNA binding properties.
    Braña MF; Cacho M; García MA; de Pascual-Teresa B; Ramos A; Domínguez MT; Pozuelo JM; Abradelo C; Rey-Stolle MF; Yuste M; Báñez-Coronel M; Lacal JC
    J Med Chem; 2004 Mar; 47(6):1391-9. PubMed ID: 14998328
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.