BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 10504231)

  • 1. Mapping of a DNA binding region of the PI-sceI homing endonuclease by affinity cleavage and alanine-scanning mutagenesis.
    Hu D; Crist M; Duan X; Gimble FS
    Biochemistry; 1999 Sep; 38(39):12621-8. PubMed ID: 10504231
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural and functional analysis of the homing endonuclease PI-sceI by limited proteolytic cleavage and molecular cloning of partial digestion products.
    Pingoud V; Grindl W; Wende W; Thole H; Pingoud A
    Biochemistry; 1998 Jun; 37(22):8233-43. PubMed ID: 9609720
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Substitutions in conserved dodecapeptide motifs that uncouple the DNA binding and DNA cleavage activities of PI-SceI endonuclease.
    Gimble FS; Stephens BW
    J Biol Chem; 1995 Mar; 270(11):5849-56. PubMed ID: 7890714
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Substrate recognition and induced DNA distortion by the PI-SceI endonuclease, an enzyme generated by protein splicing.
    Gimble FS; Wang J
    J Mol Biol; 1996 Oct; 263(2):163-80. PubMed ID: 8913299
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Probing the structure of the PI-SceI-DNA complex by affinity cleavage and affinity photocross-linking.
    Hu D; Crist M; Duan X; Quiocho FA; Gimble FS
    J Biol Chem; 2000 Jan; 275(4):2705-12. PubMed ID: 10644733
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of Asp218 and Asp326 as the principal Mg2+ binding ligands of the homing endonuclease PI-SceI.
    Schöttler S; Wende W; Pingoud V; Pingoud A
    Biochemistry; 2000 Dec; 39(51):15895-900. PubMed ID: 11123916
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Photocross-linking of the homing endonuclease PI-SceI to its recognition sequence.
    Pingoud V; Thole H; Christ F; Grindl W; Wende W; Pingoud A
    J Biol Chem; 1999 Apr; 274(15):10235-43. PubMed ID: 10187809
    [TBL] [Abstract][Full Text] [Related]  

  • 8. High resolution crystal structure of domain I of the Saccharomyces cerevisiae homing endonuclease PI-SceI.
    Werner E; Wende W; Pingoud A; Heinemann U
    Nucleic Acids Res; 2002 Sep; 30(18):3962-71. PubMed ID: 12235380
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of Lys-403 in the PI-SceI homing endonuclease as part of a symmetric catalytic center.
    Gimble FS; Duan X; Hu D; Quiocho FA
    J Biol Chem; 1998 Nov; 273(46):30524-9. PubMed ID: 9804821
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Amino acid residues in both the protein splicing and endonuclease domains of the PI-SceI intein mediate DNA binding.
    He Z; Crist M; Yen H; Duan X; Quiocho FA; Gimble FS
    J Biol Chem; 1998 Feb; 273(8):4607-15. PubMed ID: 9468518
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The monomeric homing endonuclease PI-SceI has two catalytic centres for cleavage of the two strands of its DNA substrate.
    Christ F; Schoettler S; Wende W; Steuer S; Pingoud A; Pingoud V
    EMBO J; 1999 Dec; 18(24):6908-16. PubMed ID: 10601013
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA recognition by the homing endonuclease PI-SceI involves a divalent metal ion cofactor-induced conformational change.
    Noël AJ; Wende W; Pingoud A
    J Biol Chem; 2004 Feb; 279(8):6794-804. PubMed ID: 14634013
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The protein splicing domain of the homing endonuclease PI-sceI is responsible for specific DNA binding.
    Grindl W; Wende W; Pingoud V; Pingoud A
    Nucleic Acids Res; 1998 Apr; 26(8):1857-62. PubMed ID: 9518476
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Crystal structure of the intein homing endonuclease PI-SceI bound to its recognition sequence.
    Moure CM; Gimble FS; Quiocho FA
    Nat Struct Biol; 2002 Oct; 9(10):764-70. PubMed ID: 12219083
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PI-PfuI and PI-PfuII, intein-coded homing endonucleases from Pyrococcus furiosus. II. Characterization Of the binding and cleavage abilities by site-directed mutagenesis.
    Komori K; Ichiyanagi K; Morikawa K; Ishino Y
    Nucleic Acids Res; 1999 Nov; 27(21):4175-82. PubMed ID: 10518608
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Degeneration of a homing endonuclease and its target sequence in a wild yeast strain.
    Gimble FS
    Nucleic Acids Res; 2001 Oct; 29(20):4215-23. PubMed ID: 11600710
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Analysis of binding and cleavage of DNA by the gene conversion PI-SCEI endonuclease using site-directed mutagenesis].
    Wende W; Schöttler S; Grindl W; Christ F; Steuer S; Nöel AJ; Pingoud V; Pingoud A
    Mol Biol (Mosk); 2000; 34(6):1054-64. PubMed ID: 11186005
    [No Abstract]   [Full Text] [Related]  

  • 18. Binding, bending and cleavage of DNA substrates by the homing endonuclease Pl-SceI.
    Wende W; Grindl W; Christ F; Pingoud A; Pingoud V
    Nucleic Acids Res; 1996 Nov; 24(21):4123-32. PubMed ID: 8932361
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Insertion of a reversible redox switch into a rare-cutting DNA endonuclease.
    Posey KL; Gimble FS
    Biochemistry; 2002 Feb; 41(7):2184-90. PubMed ID: 11841209
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structure of PI-SceI, a homing endonuclease with protein splicing activity.
    Duan X; Gimble FS; Quiocho FA
    Cell; 1997 May; 89(4):555-64. PubMed ID: 9160747
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.