BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

314 related articles for article (PubMed ID: 10508158)

  • 1. Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases.
    Deveraux QL; Leo E; Stennicke HR; Welsh K; Salvesen GS; Reed JC
    EMBO J; 1999 Oct; 18(19):5242-51. PubMed ID: 10508158
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibitor of apoptosis protein hILP undergoes caspase-mediated cleavage during T lymphocyte apoptosis.
    Johnson DE; Gastman BR; Wieckowski E; Wang GQ; Amoscato A; Delach SM; Rabinowich H
    Cancer Res; 2000 Apr; 60(7):1818-23. PubMed ID: 10766165
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A single BIR domain of XIAP sufficient for inhibiting caspases.
    Takahashi R; Deveraux Q; Tamm I; Welsh K; Assa-Munt N; Salvesen GS; Reed JC
    J Biol Chem; 1998 Apr; 273(14):7787-90. PubMed ID: 9525868
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting the X-linked inhibitor of apoptosis protein through 4-substituted azabicyclo[5.3.0]alkane smac mimetics. Structure, activity, and recognition principles.
    Mastrangelo E; Cossu F; Milani M; Sorrentino G; Lecis D; Delia D; Manzoni L; Drago C; Seneci P; Scolastico C; Rizzo V; Bolognesi M
    J Mol Biol; 2008 Dec; 384(3):673-89. PubMed ID: 18851976
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis.
    Srinivasula SM; Hegde R; Saleh A; Datta P; Shiozaki E; Chai J; Lee RA; Robbins PD; Fernandes-Alnemri T; Shi Y; Alnemri ES
    Nature; 2001 Mar; 410(6824):112-6. PubMed ID: 11242052
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Apoptosis inhibition in ischemic brain by intraperitoneal PTD-BIR3-RING (XIAP).
    Fan YF; Lu CZ; Xie J; Zhao YX; Yang GY
    Neurochem Int; 2006 Jan; 48(1):50-9. PubMed ID: 16293346
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs.
    Zobel K; Wang L; Varfolomeev E; Franklin MC; Elliott LO; Wallweber HJ; Okawa DC; Flygare JA; Vucic D; Fairbrother WJ; Deshayes K
    ACS Chem Biol; 2006 Sep; 1(8):525-33. PubMed ID: 17168540
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Determination of the sequence specificity of XIAP BIR domains by screening a combinatorial peptide library.
    Sweeney MC; Wang X; Park J; Liu Y; Pei D
    Biochemistry; 2006 Dec; 45(49):14740-8. PubMed ID: 17144666
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A mechanistic insight into SMAC peptide interference with XIAP-Bir2 inhibition of executioner caspases.
    Abhari BA; Davoodi J
    J Mol Biol; 2008 Sep; 381(3):645-54. PubMed ID: 18619610
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP.
    Sun C; Cai M; Gunasekera AH; Meadows RP; Wang H; Chen J; Zhang H; Wu W; Xu N; Ng SC; Fesik SW
    Nature; 1999 Oct; 401(6755):818-22. PubMed ID: 10548111
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ML-IAP).
    Franklin MC; Kadkhodayan S; Ackerly H; Alexandru D; Distefano MD; Elliott LO; Flygare JA; Mausisa G; Okawa DC; Ong D; Vucic D; Deshayes K; Fairbrother WJ
    Biochemistry; 2003 Jul; 42(27):8223-31. PubMed ID: 12846571
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Study of caspase inhibitors for limiting death in mammalian cell culture.
    Sauerwald TM; Oyler GA; Betenbaugh MJ
    Biotechnol Bioeng; 2003 Feb; 81(3):329-40. PubMed ID: 12474256
    [TBL] [Abstract][Full Text] [Related]  

  • 13. N-phenethyl-2-phenylacetamide isolated from Xenorhabdus nematophilus induces apoptosis through caspase activation and calpain-mediated Bax cleavage in U937 cells.
    Hwang SY; Paik S; Park SH; Kim HS; Lee IS; Kim SP; Baek WK; Suh MH; Kwon TK; Park JW; Park JB; Lee JJ; Suh SI
    Int J Oncol; 2003 Jan; 22(1):151-7. PubMed ID: 12469198
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria.
    Zhang XD; Zhang XY; Gray CP; Nguyen T; Hersey P
    Cancer Res; 2001 Oct; 61(19):7339-48. PubMed ID: 11585775
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of the XIAP inhibitor Embelin on TRAIL-induced apoptosis of pancreatic cancer cells.
    Mori T; Doi R; Kida A; Nagai K; Kami K; Ito D; Toyoda E; Kawaguchi Y; Uemoto S
    J Surg Res; 2007 Oct; 142(2):281-6. PubMed ID: 17640673
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Alpha-fetoprotein antagonizes X-linked inhibitor of apoptosis protein anticaspase activity and disrupts XIAP-caspase interaction.
    Dudich E; Semenkova L; Dudich I; Denesyuk A; Tatulov E; Korpela T
    FEBS J; 2006 Aug; 273(16):3837-49. PubMed ID: 16869888
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Caspase-mediated cleavage converts Livin from an antiapoptotic to a proapoptotic factor: implications for drug-resistant melanoma.
    Nachmias B; Ashhab Y; Bucholtz V; Drize O; Kadouri L; Lotem M; Peretz T; Mandelboim O; Ben-Yehuda D
    Cancer Res; 2003 Oct; 63(19):6340-9. PubMed ID: 14559822
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer.
    Oost TK; Sun C; Armstrong RC; Al-Assaad AS; Betz SF; Deckwerth TL; Ding H; Elmore SW; Meadows RP; Olejniczak ET; Oleksijew A; Oltersdorf T; Rosenberg SH; Shoemaker AR; Tomaselli KJ; Zou H; Fesik SW
    J Med Chem; 2004 Aug; 47(18):4417-26. PubMed ID: 15317454
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Metabolic inhibitors sensitize for CD95 (APO-1/Fas)-induced apoptosis by down-regulating Fas-associated death domain-like interleukin 1-converting enzyme inhibitory protein expression.
    Fulda S; Meyer E; Debatin KM
    Cancer Res; 2000 Jul; 60(14):3947-56. PubMed ID: 10919673
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Specific proteolysis of the A-kinase-anchoring protein 149 at the Asp582 residue by caspases during apoptosis.
    Yoo H; Cha HJ; Lee J; Yu EO; Bae S; Jung JH; Sohn I; Lee SJ; Yang KH; Woo SH; Seo SK; Park IC; Kim CS; Jin YW; Ahn SK
    Oncol Rep; 2008 Jun; 19(6):1577-82. PubMed ID: 18497968
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.