102 related articles for article (PubMed ID: 10508444)
1. Synthesis and SAR of 1-alkyl-2-phenylethylamine derivatives designed from N,N-dipropyl-4-methoxy-3-(2-phenylethoxy)phenylethylamine to discover sigma(1) ligands.
Nakazato A; Kumagai T; Ohta K; Chaki S; Okuyama S; Tomisawa K
J Med Chem; 1999 Sep; 42(19):3965-70. PubMed ID: 10508444
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis, structure-activity relationships, and biological characterization of novel arylalkoxyphenylalkylamine sigma ligands as potential antipsychotic drugs.
Nakazato A; Ohta K; Sekiguchi Y; Okuyama S; Chaki S; Kawashima Y; Hatayama K
J Med Chem; 1999 Mar; 42(6):1076-87. PubMed ID: 10090790
[TBL] [Abstract][Full Text] [Related]
3. NE-100, a novel sigma receptor ligand: in vivo tests.
Okuyama S; Imagawa Y; Ogawa S; Araki H; Ajima A; Tanaka M; Muramatsu M; Nakazato A; Yamaguchi K; Yoshida M
Life Sci; 1993; 53(18):PL285-90. PubMed ID: 7901723
[TBL] [Abstract][Full Text] [Related]
4. NE-100, a novel potent sigma ligand, preferentially binds to sigma 1 binding sites in guinea pig brain.
Chaki S; Tanaka M; Muramatsu M; Otomo S
Eur J Pharmacol; 1994 Jan; 251(1):R1-2. PubMed ID: 8137864
[TBL] [Abstract][Full Text] [Related]
5. Differences in cytochrome P450 forms involved in the metabolism of N,N-dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100), a novel sigma ligand, in human liver and intestine.
Yamamoto T; Hagima N; Nakamura M; Kohno Y; Nagata K; Yamazoe Y
Drug Metab Dispos; 2003 Jan; 31(1):60-6. PubMed ID: 12485954
[TBL] [Abstract][Full Text] [Related]
6. Effects of a novel, selective, sigma1-ligand, MS-377, on phencyclidine-induced behaviour.
Takahashi S; Takagi K; Horikomi K
Naunyn Schmiedebergs Arch Pharmacol; 2001 Jul; 364(1):81-6. PubMed ID: 11485043
[TBL] [Abstract][Full Text] [Related]
7. Differentiation of sigma ligand-activated receptor subtypes that modulate NMDA-evoked [3H]-noradrenaline release in rat hippocampal slices.
Monnet FP; de Costa BR; Bowen WD
Br J Pharmacol; 1996 Sep; 119(1):65-72. PubMed ID: 8872358
[TBL] [Abstract][Full Text] [Related]
8. Effect of NE-100, a novel sigma receptor ligand, on phencyclidine-induced cognitive dysfunction.
Ogawa S; Okuyama S; Araki H; Otomo S
Eur J Pharmacol; 1994 Sep; 263(1-2):9-15. PubMed ID: 7821367
[TBL] [Abstract][Full Text] [Related]
9. The involvement of sigma receptors in the choice reaction performance deficits induced by phencyclidine.
Jin J; Yamamoto T; Watanabe S
Eur J Pharmacol; 1997 Jan; 319(2-3):147-52. PubMed ID: 9042584
[TBL] [Abstract][Full Text] [Related]
10. Lack of neuroprotective effect of sigma receptor ligands in the neurotoxicity of p-chloroamphetamine in rat brain.
Narita N; Hashimoto K; Iyo M; Minabe Y; Yamazaki K
Eur J Pharmacol; 1995 Oct; 293(3):277-80. PubMed ID: 8666047
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and preliminary evaluation of [11C]NE-100 labeled in two different positions as a PET sigma receptor ligand.
Ishiwata K; Noguchi J; Ishii S; Hatano K; Ito K; Nabeshima T; Senda M
Nucl Med Biol; 1998 Apr; 25(3):195-202. PubMed ID: 9620623
[TBL] [Abstract][Full Text] [Related]
12. Effect of NE-100, a novel sigma receptor ligand, on phencyclidine- induced delayed cognitive dysfunction in rats.
Okuyama S; Ogawa S; Nakazato A; Tomizawa K
Neurosci Lett; 1995 Apr; 189(1):60-2. PubMed ID: 7603628
[TBL] [Abstract][Full Text] [Related]
13. NE-100, a novel sigma ligand: effects on [3H]TCP binding to intact primary cultured neuronal cells.
Yamamoto H; Yamamoto T; Sagi N; Okuyama S; Kawai N; Baba A; Moroji T
Life Sci; 1995; 56(2):PL39-43. PubMed ID: 7823755
[TBL] [Abstract][Full Text] [Related]
14. NE-100, a novel sigma receptor ligand: effect on phencyclidine-induced behaviors in rats, dogs and monkeys.
Okuyama S; Imagawa Y; Sakagawa T; Nakazato A; Yamaguchi K; Katoh M; Yamada S; Araki H; Otomo S
Life Sci; 1994; 55(7):PL133-8. PubMed ID: 8041225
[TBL] [Abstract][Full Text] [Related]
15. In vivo functional interaction between phencyclidine binding sites and sigma receptors to produce head-weaving behavior in rats.
Kitaichi K; Noda Y; Hasegawa T; Furukawa H; Nabeshima T
Eur J Pharmacol; 1996 Dec; 318(2-3):205-11. PubMed ID: 9016907
[TBL] [Abstract][Full Text] [Related]
16. Sigma 1 receptor subtype is involved in the relief of behavioral despair in the mouse forced swimming test.
Matsuno K; Kobayashi T; Tanaka MK; Mita S
Eur J Pharmacol; 1996 Oct; 312(3):267-71. PubMed ID: 8894608
[TBL] [Abstract][Full Text] [Related]
17. The sigma-selective ligand NE-100 attenuates the effect of phencyclidine in a rat diving model.
Ogawa S; Okuyama S; Tsuchida K; Araki H; Otomo S
Gen Pharmacol; 1995 Jan; 26(1):177-82. PubMed ID: 7713358
[TBL] [Abstract][Full Text] [Related]
18. A sigma-1 receptor antagonist (NE-100) prevents tunicamycin-induced cell death via GRP78 induction in hippocampal cells.
Ono Y; Tanaka H; Tsuruma K; Shimazawa M; Hara H
Biochem Biophys Res Commun; 2013 May; 434(4):904-9. PubMed ID: 23618865
[TBL] [Abstract][Full Text] [Related]
19. Attenuation of scopolamine-induced and age-associated memory impairments by the sigma and 5-hydroxytryptamine(1A) receptor agonist OPC-14523 (1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-methoxy-3,4-dihydro-2[1H]-quinolinone monomethanesulfonate).
Tottori K; Nakai M; Uwahodo Y; Miwa T; Yamada S; Oshiro Y; Kikuchi T; Altar CA
J Pharmacol Exp Ther; 2002 Apr; 301(1):249-57. PubMed ID: 11907181
[TBL] [Abstract][Full Text] [Related]
20. A-Current down-modulated by sigma receptor in frog pituitary melanotrope cells through a G protein-dependent pathway.
Soriani O; Foll FL; Roman F; Monnet FP; Vaudry H; Cazin L
J Pharmacol Exp Ther; 1999 Apr; 289(1):321-8. PubMed ID: 10087020
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]